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Tracheal intubation in the critically ill patient.
Russotto V, Rahmani LS, Parotto M, Bellani G, Laffey JG. Russotto V, et al. Eur J Anaesthesiol. 2022 May 1;39(5):463-472. doi: 10.1097/EJA.0000000000001627. Epub 2021 Nov 18. Eur J Anaesthesiol. 2022. PMID: 34799497 Review.
Indeed, 45% of patients undergoing intubation experience at least one major peri-intubation adverse event, with cardiovascular instability being the most common event reported in 43%, followed by severe hypoxemia in 9% and cardiac arrest in 3% o …
Indeed, 45% of patients undergoing intubation experience at least one major peri-intubation adverse event, with card …
Prevalence of peri-intubation major adverse events among critically ill patients: A systematic review and meta analysis.
Downing J, Yardi I, Ren C, Cardona S, Zahid M, Tang K, Bzhilyanskaya V, Patel P, Pourmand A, Tran QK. Downing J, et al. Am J Emerg Med. 2023 Sep;71:200-216. doi: 10.1016/j.ajem.2023.06.046. Epub 2023 Jun 28. Am J Emerg Med. 2023. PMID: 37437438
BACKGROUND: Peri-intubation major adverse events (MAEs) are potentially preventable and associated with poor patient outcomes. ...Intubation for hemodynamic instability was associated with higher rates of MAEs, while intubation for airway protection wa …
BACKGROUND: Peri-intubation major adverse events (MAEs) are potentially preventable and associated with poor patient ou …
Emergency Airway Management: A Look into the Practice, Rate of Success, and Adverse Events of 94 Endotracheal Intubations.
Fadhlillah F, Bury S, Grocholski E, Dean M, Refson A. Fadhlillah F, et al. J Emerg Trauma Shock. 2020 Jan-Mar;13(1):58-61. doi: 10.4103/JETS.JETS_100_19. Epub 2020 Mar 19. J Emerg Trauma Shock. 2020. PMID: 32395052 Free PMC article.
RESULTS: There were 94 intubations, male to female ratio 1.8:1. The most common indication was for airway protection (n = 35), followed by respiratory failure (n = 23). ...It adds to the growing call for better standardization and provision of care to patients with a deter …
RESULTS: There were 94 intubations, male to female ratio 1.8:1. The most common indication was for airway protection (n = 35), follow …
Pathophysiology of Volume Administration in Septic Shock and the Role of the Clinical Pharmacist.
Bissell BD, Mefford B. Bissell BD, et al. Ann Pharmacother. 2020 Apr;54(4):388-396. doi: 10.1177/1060028019887160. Epub 2019 Nov 6. Ann Pharmacother. 2020. PMID: 31694386 Review.
Data Synthesis: Although early fluid resuscitation may be a necessary component to decrease mortality in the majority of patients with septic shock admitted to the intensive care unit (ICU), the benefit of continued administration after the first 24 hours is uncerta …
Data Synthesis: Although early fluid resuscitation may be a necessary component to decrease mortality in the majority of patients wit …
A Nationwide, Prospective Study of Tracheal Intubation in Critically Ill Adults in Spain: Management, Associated Complications, and Outcomes.
Garnacho-Montero J, Gordillo-Escobar E, Trenado J, Gordo F, Fisac L, García-Prieto E, López-Martin C, Abella A, Jiménez JR, García-Garmendia JL; Intubation Prospective (INTUPROS) Study Investigators. Garnacho-Montero J, et al. Crit Care Med. 2024 May 1;52(5):786-797. doi: 10.1097/CCM.0000000000006198. Epub 2024 Jan 23. Crit Care Med. 2024. PMID: 38259143
The multivariate analysis identified seven variables independently associated with a major adverse event whereas the use of neuromuscular blocking agents (NMBAs) was associated with reduced odds of major adverse events. ...CONCLUSIONS: A …
The multivariate analysis identified seven variables independently associated with a major adverse event whereas the us …
Physiologically Difficult Airway in the Patient with Severe Hypotension and Metabolic Acidosis.
Capone J, Gluncic V, Lukic A, Candido KD. Capone J, et al. Case Rep Anesthesiol. 2020 Sep 4;2020:8821827. doi: 10.1155/2020/8821827. eCollection 2020. Case Rep Anesthesiol. 2020. PMID: 32953182 Free PMC article.
Combination of hypotension and severe metabolic acidosis is particularly a challenging setting for airway management and a major risk factor for adverse events, including cardiopulmonary arrest. ...In addition, sustaining spontaneous ventilation …
Combination of hypotension and severe metabolic acidosis is particularly a challenging setting for airway management and a …
Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a rapid review.
Valk SJ, Piechotta V, Chai KL, Doree C, Monsef I, Wood EM, Lamikanra A, Kimber C, McQuilten Z, So-Osman C, Estcourt LJ, Skoetz N. Valk SJ, et al. Cochrane Database Syst Rev. 2020 May 14;5(5):CD013600. doi: 10.1002/14651858.CD013600. Cochrane Database Syst Rev. 2020. PMID: 32406927 Free PMC article. Updated.
We are very uncertain whether or not convalescent plasma therapy affects the risk of moderate to severe adverse events (very low-certainty evidence). Serious adverse events One study (3 participants) reported one serious adverse event. .. …
We are very uncertain whether or not convalescent plasma therapy affects the risk of moderate to severe adverse events (very l …
Acetate Ringer's solution versus 0.9% saline for septic patients: study protocol for a multi-center parallel controlled trial.
Liu F, Zhang J, Zhu Y, Su L, Li Y, He L, Yu L, Peng Z. Liu F, et al. Trials. 2021 Jan 25;22(1):89. doi: 10.1186/s13063-020-05007-5. Trials. 2021. PMID: 33494795 Free PMC article.
METHODS/DESIGN: The investigators designed a pragmatic, multi-center parallel controlled trial recruiting 312 patients who are diagnosed with sepsis/septic shock in the intensive care unit (ICU) and will be assigned with either acetate Ringer's solution or saline in the co …
METHODS/DESIGN: The investigators designed a pragmatic, multi-center parallel controlled trial recruiting 312 patients who are diagnosed wit …