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Implications of Adverse Outcomes Associated with Antipsychotics in Older Patients with Dementia: A 2011-2022 Update.
Rogowska M, Thornton M, Creese B, Velayudhan L, Aarsland D, Ballard C, Tsamakis K, Stewart R, Mueller C. Rogowska M, et al. Drugs Aging. 2023 Jan;40(1):21-32. doi: 10.1007/s40266-022-00992-5. Epub 2022 Dec 14. Drugs Aging. 2023. PMID: 36513918 Free PMC article. Review.
The first-line management of the neuropsychiatric symptoms of dementia should be non-pharmacological. If medications are required, antipsychotics are commonly chosen. Second-generation antipsychotics such as risperidone, olanzapine, quetiapine and aripiprazole are p …
The first-line management of the neuropsychiatric symptoms of dementia should be non-pharmacological. If medications are required, antips …
Clozapine-Related Thromboembolic Events.
Pallares Vela E, Dave P, Cancarevic I. Pallares Vela E, et al. Cureus. 2021 Aug 4;13(8):e16883. doi: 10.7759/cureus.16883. eCollection 2021 Aug. Cureus. 2021. PMID: 34513458 Free PMC article. Review.
Clozapine is an atypical antipsychotic used for treatment-resistant schizophrenia. Venous thromboembolism (VTE) is a rare side effect of clozapine which can be fatal. ...In total, 68.57% were prescribed other medications at VTE onset, and 60% were being treated with …
Clozapine is an atypical antipsychotic used for treatment-resistant schizophrenia. Venous thromboembolism (VTE) is a rare side …
Impact of drugs on venous thromboembolism risk in surgical patients.
Kovačič APM, Caprnda M, Mrhar A, Kubatka P, Locatelli I, Zolakova B, Gaspar L, Prosecky R, Kruzliak P, Staffa R, Rodrigo L, Radonak J, Petrovič D. Kovačič APM, et al. Eur J Clin Pharmacol. 2019 Jun;75(6):751-767. doi: 10.1007/s00228-019-02636-x. Epub 2019 Feb 5. Eur J Clin Pharmacol. 2019. PMID: 30719565 Review.
Tricyclic antidepressants, low-potency serotonin reuptake inhibitors, and antipsychotics have been associated with increased risk of VTE. The use of diuretics in the perioperative period is poorly researched; however, hyponatremia is considered a risk factor. ...CONCLUSION …
Tricyclic antidepressants, low-potency serotonin reuptake inhibitors, and antipsychotics have been associated with increased risk of …
Fatal pulmonary embolism in patients on antipsychotics: case series, systematic review and meta-analysis.
Manoubi SA, Boussaid M, Brahim O, Ouanes S, Mahjoub Y, Zarrouk L, Mesrati MA, Aissaoui A. Manoubi SA, et al. Asian J Psychiatr. 2022 Jul;73:103105. doi: 10.1016/j.ajp.2022.103105. Epub 2022 Apr 12. Asian J Psychiatr. 2022. PMID: 35452966 Review.
Since the 1950 s, several studies have reported that patients using first generation and/or second-generation antipsychotics had increased risk of venous thromboembolism events. These events include deep vein thrombosis and/or pulmonary embolism (PE). However, data …
Since the 1950 s, several studies have reported that patients using first generation and/or second-generation antipsychotics had incr …
The plausible mechanisms of tramadol for treatment of COVID-19.
El-Ashmawy NE, Lashin AA, Okasha KM, Abo Kamer AM, Mostafa TM, El-Aasr M, Goda AE, Haggag YA, Tawfik HO, Abo-Saif MA. El-Ashmawy NE, et al. Med Hypotheses. 2021 Jan;146:110468. doi: 10.1016/j.mehy.2020.110468. Epub 2020 Dec 22. Med Hypotheses. 2021. PMID: 33385878 Free PMC article. Review.
Tramadol owing to its hypocoagulable effect may protect against venous thromboembolism in these patients. Moreover, tramadol can exert a cardioprotective effect via decreasing lactate dehydrogenase (LDH) level which is elevated in most of patients with COVID-19. ...
Tramadol owing to its hypocoagulable effect may protect against venous thromboembolism in these patients. Moreover, tramadol can exer …
Antipsychotic use and risk of life-threatening medical events: umbrella review of observational studies.
Papola D, Ostuzzi G, Gastaldon C, Morgano GP, Dragioti E, Carvalho AF, Fusar-Poli P, Correll CU, Solmi M, Barbui C. Papola D, et al. Acta Psychiatr Scand. 2019 Sep;140(3):227-243. doi: 10.1111/acps.13066. Epub 2019 Jul 25. Acta Psychiatr Scand. 2019. PMID: 31264708
OBJECTIVE: To quantify the risk of hip fracture, thromboembolism, stroke, myocardial infarction, pneumonia and sudden cardiac death associated with exposure to antipsychotics. ...CONCLUSION: The most robust results were found for the risk of pneumonia, followed by t …
OBJECTIVE: To quantify the risk of hip fracture, thromboembolism, stroke, myocardial infarction, pneumonia and sudden cardiac death a …
Incidence of Venous Thromboembolism Among Commonly Prescribed Second-Generation Antipsychotics.
Paulmann R, Backe K, Pinsonnault J, Humble M, Kelly K. Paulmann R, et al. J Pharm Pract. 2023 Jun 22:8971900231184965. doi: 10.1177/08971900231184965. Online ahead of print. J Pharm Pract. 2023. PMID: 37347841
Background: Second-generation antipsychotics (SGAs) are commonly prescribed medications used to treat a variety of mental health conditions. Recent data has correlated antipsychotic medications with venous thromboembolism (VTE). SGAs have diverse side effect …
Background: Second-generation antipsychotics (SGAs) are commonly prescribed medications used to treat a variety of mental health cond …
COVID-19 and Antipsychotic Therapy: Unraveling the Thrombosis Risk.
Dho-Nagy EA, Brassai A, Lechsner P, Ureche C, Bán EG. Dho-Nagy EA, et al. Int J Mol Sci. 2024 Jan 9;25(2):818. doi: 10.3390/ijms25020818. Int J Mol Sci. 2024. PMID: 38255892 Free PMC article. Review.
In the context of the COVID-19 pandemic, this study investigates the potential correlation between the increased use of antipsychotic medications and the rising incidence of venous thromboembolism (VTE). ...This approach allowed for a nuanced examination of the hist …
In the context of the COVID-19 pandemic, this study investigates the potential correlation between the increased use of antipsychotic …
Evidence-based perioperative diagnosis and management of pulmonary embolism: A systematic review.
Abate LG, Bayable SD, Fetene MB. Abate LG, et al. Ann Med Surg (Lond). 2022 Apr 28;77:103684. doi: 10.1016/j.amsu.2022.103684. eCollection 2022 May. Ann Med Surg (Lond). 2022. PMID: 35638051 Free PMC article. Review.
CONCLUSION: All perioperative patients, especially trauma victims, prostate or orthopedic surgery, malignancy, immobility, and obesity; smokers; and oral contraceptive users, antipsychotic medications are at increased risk of venous thromboembolism and need special …
CONCLUSION: All perioperative patients, especially trauma victims, prostate or orthopedic surgery, malignancy, immobility, and obesity; smok …
The risk of pulmonary embolism in the context of various clinical situations and management in psychiatric patients.
Sapota-Zaręba K, Nasierowski T. Sapota-Zaręba K, et al. Psychiatr Pol. 2023 Oct 31;57(5):955-965. doi: 10.12740/PP/152585. Epub 2023 Oct 31. Psychiatr Pol. 2023. PMID: 38345121 Free article. Review. English, Polish.
This mainly results from additional thromboembolic risk factors associated with symptoms and treatment of mental disorders. ...Current data on potentially thrombotic effect of antipsychotics, antidepressants and electroconvulsive therapy are summarised. ...
This mainly results from additional thromboembolic risk factors associated with symptoms and treatment of mental disorders. ...Curren …
52 results