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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1961 1
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1975 7
1976 6
1977 1
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1980 21
1981 18
1982 21
1983 25
1984 69
1985 53
1986 46
1987 59
1988 56
1989 71
1990 72
1991 93
1992 79
1993 76
1994 61
1995 47
1996 54
1997 57
1998 52
1999 40
2000 49
2001 40
2002 41
2003 60
2004 52
2005 54
2006 36
2007 32
2008 39
2009 41
2010 42
2011 37
2012 45
2013 51
2014 36
2015 24
2016 28
2017 36
2018 42
2019 30
2020 33
2021 38
2022 36
2023 29
2024 15

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1,990 results

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Page 1
Propafenone.
Funck-Brentano C, Kroemer HK, Lee JT, Roden DM. Funck-Brentano C, et al. N Engl J Med. 1990 Feb 22;322(8):518-25. doi: 10.1056/NEJM199002223220806. N Engl J Med. 1990. PMID: 2405273 Review. No abstract available.
Effects of propafenone and 5-hydroxy-propafenone on hKv1.5 channels.
Franqueza L, Valenzuela C, Delpón E, Longobardo M, Caballero R, Tamargo J. Franqueza L, et al. Br J Pharmacol. 1998 Nov;125(5):969-78. doi: 10.1038/sj.bjp.0702129. Br J Pharmacol. 1998. PMID: 9846634 Free PMC article.
1. The goal of this study was to analyse the effects of propafenone and its major metabolite, 5-hydroxy-propafenone, on a human cardiac K+ channel (hKv1.5) stably expressed in Ltk- cells and using the whole-cell configuration of the patch-clamp technique. 2. Prop …
1. The goal of this study was to analyse the effects of propafenone and its major metabolite, 5-hydroxy-propafenone, on a huma …
Simultaneous determination of serum propafenone and its metabolites using high-performance liquid chromatography.
Shirayama Y, Doki K, Sekiguchi Y, Aonuma K, Kohda Y, Homma M. Shirayama Y, et al. Biomed Chromatogr. 2018 Feb;32(2). doi: 10.1002/bmc.4099. Epub 2017 Oct 15. Biomed Chromatogr. 2018. PMID: 28929504
The calibration curves were linear for a concentration range of 12.5-1500 ng/mL for propafenone and 2-500 ng/mL for 5-OHP and NDPP (r > 0.999). CVs in the intraday assays were 1.0-3.8% for propafenone, 0.6-2.0% for 5-OHP and 0.6-1.7% for NDPP. CVs in interday ass …
The calibration curves were linear for a concentration range of 12.5-1500 ng/mL for propafenone and 2-500 ng/mL for 5-OHP and NDPP (r …
Propafenone-theophylline interaction.
Spinler SA, Gammaitoni A, Charland SL, Hurwitz J. Spinler SA, et al. Pharmacotherapy. 1993 Jan-Feb;13(1):68-71. Pharmacotherapy. 1993. PMID: 8437970
Both propafenone and theophylline are hepatically metabolized by the cytochrome P-450 enzyme system. The decrease in theophylline clearance of 25% to 69% in this patient may be due to competitive metabolism resulting in enzyme inhibition and increased theophylline concentr …
Both propafenone and theophylline are hepatically metabolized by the cytochrome P-450 enzyme system. The decrease in theophylline cle …
Propafenone.
Veale D, McComb JM, Gibson GJ. Veale D, et al. Lancet. 1990 Apr 21;335(8695):979. doi: 10.1016/0140-6736(90)91048-f. Lancet. 1990. PMID: 1970054 No abstract available.
[Propafenone poisoning].
Sadeg N, Richecoeur J, Dumontet M. Sadeg N, et al. Therapie. 2003 Jul-Aug;58(4):381-3; discussion 387. doi: 10.2515/therapie:2003061. Therapie. 2003. PMID: 14679682 French. No abstract available.
Clinical pharmacokinetics of propafenone.
Hii JT, Duff HJ, Burgess ED. Hii JT, et al. Clin Pharmacokinet. 1991 Jul;21(1):1-10. doi: 10.2165/00003088-199121010-00001. Clin Pharmacokinet. 1991. PMID: 1914339 Review.
Propafenone is a class 1C antiarrhythmic agent which is administered as a racemate of S(+)- and R(-)-enantiomers. ...Doses of these drugs should therefore be decreased if they are coadministered with propafenone....
Propafenone is a class 1C antiarrhythmic agent which is administered as a racemate of S(+)- and R(-)-enantiomers. ...Doses of these d …
New antiarrhythmic drugs in pediatric use: propafenone.
Paul T, Janousek J. Paul T, et al. Pediatr Cardiol. 1994 Jul-Aug;15(4):190-7. doi: 10.1007/BF00800674. Pediatr Cardiol. 1994. PMID: 7991437 Review.
In patients with atrioventricular nodal reentry tachycardia, propafenone is able to block conduction in the fast conducting pathway. ...In children with ventricular dysrhythmias, efficacy seems to be related to the underlying cardiac diagnosis. Propafenone is well t …
In patients with atrioventricular nodal reentry tachycardia, propafenone is able to block conduction in the fast conducting pathway. …
Propafenone: a new antiarrhythmic agent.
Chow MS, Lebsack C, Hilleman D. Chow MS, et al. Clin Pharm. 1988 Dec;7(12):869-77. Clin Pharm. 1988. PMID: 3061720 Review.
Propafenone is effective in treating ventricular tachycardia and in suppressing premature ventricular complexes (PVCs). ...Concurrent administration of digoxin, warfarin, or metoprolol with propafenone has been shown to increase the serum concentrations of those thr …
Propafenone is effective in treating ventricular tachycardia and in suppressing premature ventricular complexes (PVCs). ...Concurrent …
Characterisation of (R/S)-propafenone and its metabolites as substrates and inhibitors of P-glycoprotein.
Bachmakov I, Rekersbrink S, Hofmann U, Eichelbaum M, Fromm MF. Bachmakov I, et al. Naunyn Schmiedebergs Arch Pharmacol. 2005 Mar;371(3):195-201. doi: 10.1007/s00210-005-1025-y. Epub 2005 Apr 15. Naunyn Schmiedebergs Arch Pharmacol. 2005. PMID: 15900513
It is well known that serum concentrations of digoxin increase considerably in humans if propafenone is given simultaneously. However, it has not been investigated in detail whether propafenone and its metabolites are substrates and/or inhibitors of human P-glycopro …
It is well known that serum concentrations of digoxin increase considerably in humans if propafenone is given simultaneously. However …
1,990 results