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681 results

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Levels and profiles of pentabromodiphenyl ether contaminants in human breast milk from Riyadh, Saudi Arabia.
Yakout SM, Isa AM, El-Sayed AA, Aziz IM. Yakout SM, et al. Saudi Med J. 2023 May;44(5):450-455. doi: 10.15537/smj.2023.44.5.20220902. Saudi Med J. 2023. PMID: 37182922 Free PMC article.
OBJECTIVES: To investigate levels of pentabromodiphenyl ether (PBDEs) in breast milk samples from healthy mothers who had lived in Riyadh for the last 5 years. ...
OBJECTIVES: To investigate levels of pentabromodiphenyl ether (PBDEs) in breast milk samples from healthy mothers who had live …
Hepatic Transcriptomic Patterns in the Neonatal Rat After Pentabromodiphenyl Ether Exposure.
Dunnick JK, Shockley KR, Morgan DL, Travlos GS, Gerrish K, Ton TT, Wilson R, Brar SS, Brix AE, Waidyanatha S, Mutlu E, Pandiri AKR. Dunnick JK, et al. Toxicol Pathol. 2020 Feb;48(2):338-349. doi: 10.1177/0192623319888433. Epub 2019 Dec 12. Toxicol Pathol. 2020. PMID: 31826744 Free PMC article.
Human exposure to pentabromodiphenyl ether (PBDE) mixture (DE-71) and its PBDE-47 congener can occur both in utero and during lactation. ...
Human exposure to pentabromodiphenyl ether (PBDE) mixture (DE-71) and its PBDE-47 congener can occur both in utero and during …
2,2',4,4',5-Pentabromodiphenyl ether induces lipid accumulation throughout differentiation in 3T3-L1 and human preadipocytes in vitro.
Armstrong LE, Akinbo S, Slitt AL. Armstrong LE, et al. J Biochem Mol Toxicol. 2020 Jun;34(6):e22485. doi: 10.1002/jbt.22485. Epub 2020 Mar 4. J Biochem Mol Toxicol. 2020. PMID: 32128945
The present study examined whether the PBDE congener, BDE-99 (2,2',4,4',5-pentabromodiphenyl ether; 0.2-20 muM), enhances the adipogenesis of mouse and human preadipocyte cell models in vitro via induced lipid accumulation. 3T3-L1 mouse preadipocytes and human visce …
The present study examined whether the PBDE congener, BDE-99 (2,2',4,4',5-pentabromodiphenyl ether; 0.2-20 muM), enhances the …
Porphyrogenic effect of pentabromodiphenyl ether after repeated administration to rats.
Bruchajzer E. Bruchajzer E. Arch Toxicol. 2011 Aug;85(8):965-74. doi: 10.1007/s00204-010-0621-x. Epub 2010 Nov 28. Arch Toxicol. 2011. PMID: 21113805
Until recently, pentabromodiphenyl ether (PentaBDE) was most commonly used as a flame retardant. ...
Until recently, pentabromodiphenyl ether (PentaBDE) was most commonly used as a flame retardant. ...
Toxicology studies of a pentabromodiphenyl ether mixture [DE-71 (technical grade)] in F344/N rats and B6C3F1/N mice and toxicology and carcinogenesis studies of a pentabromodiphenyl ether mixture [DE-71 (technical grade)] in Wistar Han [Crl:WI(Han)] rats and B6C3F1/N mice (gavage studies).
National Toxicology Program. National Toxicology Program. Natl Toxicol Program Tech Rep Ser. 2016 Feb;(589):NTP-TR-589. doi: 10.22427/NTP-TR-589. Natl Toxicol Program Tech Rep Ser. 2016. PMID: 33557475 Free PMC article.
DE-71, a pentabromodiphenyl ether mixture, was used in the past as an additive flame retardant, often in furniture materials. ...
DE-71, a pentabromodiphenyl ether mixture, was used in the past as an additive flame retardant, often in furniture materials. …
BDE99 (2,2',4,4',5-pentabromodiphenyl ether) suppresses differentiation into neurotransmitter phenotypes in PC12 cells.
Slotkin TA, Card J, Infante A, Seidler FJ. Slotkin TA, et al. Neurotoxicol Teratol. 2013 May-Jun;37:13-7. doi: 10.1016/j.ntt.2013.02.001. Epub 2013 Feb 16. Neurotoxicol Teratol. 2013. PMID: 23422510 Free PMC article.
Although these agents are thyroid disruptors, it is not clear whether this mechanism alone accounts for the adverse effects. We evaluated the impact of 2,2',4,4',5-pentabromodiphenyl ether (BDE99) on PC12 cells undergoing neurodifferentiation, contrasting the effect …
Although these agents are thyroid disruptors, it is not clear whether this mechanism alone accounts for the adverse effects. We evaluated th …
Tissue localisation of tetra- and pentabromodiphenyl ether congeners (BDE-47, -85 and -99) in perinatal and adult C57BL mice.
Darnerud PO, Risberg S. Darnerud PO, et al. Chemosphere. 2006 Jan;62(3):485-93. doi: 10.1016/j.chemosphere.2005.04.004. Chemosphere. 2006. PMID: 15893803
The animals were subjected to whole-body autoradiography using (14)C-labelled 2,2',4,4'-tetrabromodiphenyl ether (BDE-47), 2,2',3,4,4'-pentabromodiphenyl ether (BDE-85) and 2,2',4,4',5-pentabromodiphenyl ether (BDE-99). ...
The animals were subjected to whole-body autoradiography using (14)C-labelled 2,2',4,4'-tetrabromodiphenyl ether (BDE-47), 2,2',3,4,4'-pe …
Primary role of cytochrome P450 2B6 in the oxidative metabolism of 2,2',4,4',6-pentabromodiphenyl ether (BDE-100) to hydroxylated BDEs.
Gross MS, Butryn DM, McGarrigle BP, Aga DS, Olson JR. Gross MS, et al. Chem Res Toxicol. 2015 Apr 20;28(4):672-81. doi: 10.1021/tx500446c. Epub 2015 Feb 12. Chem Res Toxicol. 2015. PMID: 25629761
Four metabolites were identified as 3-hydroxy-2,2',4,4',6-pentabromodiphenyl ether (3-OH-BDE-100), 5'-hydroxy-2,2',4,4',6-pentabromodiphenyl ether (5'-OH-BDE-100), 6'-hydroxy-2,2',4,4',6-pentabromodiphenyl ether (6'-OH-BDE-100), and 4'-hy …
Four metabolites were identified as 3-hydroxy-2,2',4,4',6-pentabromodiphenyl ether (3-OH-BDE-100), 5'-hydroxy-2,2',4,4',6-p …
Measurement of polybrominated diphenyl ethers and metabolites in mouse plasma after exposure to a commercial pentabromodiphenyl ether mixture.
Qiu X, Mercado-Feliciano M, Bigsby RM, Hites RA. Qiu X, et al. Environ Health Perspect. 2007 Jul;115(7):1052-8. doi: 10.1289/ehp.10011. Environ Health Perspect. 2007. PMID: 17637922 Free PMC article.
OBJECTIVES: To identify candidate metabolites, mouse plasma samples were collected after continuous oral and subcutaneous exposure to DE-71, a widely used commercial pentabromodiphenyl ether product, for 34 days. METHODS: Samples were extracted, separated into neutr …
OBJECTIVES: To identify candidate metabolites, mouse plasma samples were collected after continuous oral and subcutaneous exposure to DE-71, …
681 results