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6 conserved protein domains
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J Biol Chem. 2005 Jun 10; 280(23):22006-11. Epub 2005 Mar 16.
[J Biol Chem. 2005]
J Immunol. 2004 Jun 15; 172(12):7466-75.
[J Immunol. 2004]
Biochim Biophys Acta. 2000 Jun 21; 1492(1):259-63.
[Biochim Biophys Acta. 2000]
Ubiquitin-like modifier activating enzyme 1 [Mus musculus]gi|223461008|gb|AAI38201.1|
[AAI38201]
ubiquitin-activating enzyme E1 isoform 2 [Mus musculus]gi|209862989|ref|NP_001129557.1|
[NP_001129557]
Ubiquitin-like modifier activating enzyme 1 [Mus musculus]gi|148878383|gb|AAI45985.1|
[AAI45985]
Parkinson's diseaseParkinson's disease (PD) is a progressive neurodegenerative movement disorder that results primarily from the death of dopaminergic neurons in the substantia nigra. Mutations in alpha-synuclein, UCHL1 ... [bsid83295]
Ubiquitin mediated proteolysisProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins ... [bsid83253]
See reference mRNA sequence for the Uba1 gene (NM_009457.3).
See the other reference sequence protein isoform for the Uba1 gene (NP_001129557.1).
Also Known As: RP23-394F6.2, A1S9, AA9...
The Uba1 gene is conserved in human, chimpanzee, dog, cow, rat, zebrafish, fruit fly, mosquito, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana, rice, and P.falciparum.
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NCBI Reference Sequence: NP_033483.1