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    His3:CG33818 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3772198, updated on 29-Dec-2023

    Summary

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    Official Symbol
    His3:CG33818provided by FlyBase
    Primary source
    FLYBASE:FBgn0053818
    Locus tag
    Dmel_CG33818
    See related
    AllianceGenome:FB:FBgn0053818
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG33818; Dmel\CG33818
    Summary
    Predicted to enable nucleosomal DNA binding activity. Predicted to be involved in nucleosome assembly. Predicted to be part of nucleosome. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See His3:CG33818 in Genome Data Viewer
    Location:
    39D4-39D4; 2-54 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (21459447..21459975)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (21459447..21459975)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene histone H2A Neighboring gene small non-coding RNA 430d Neighboring gene histone H4 Neighboring gene histone H1 Neighboring gene histone H2B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of the p53 homologue from Drosophila melanogaster in the maintenance of histone H3 acetylation and response to UV-light irradiation. Rebollar E, et al. FEBS Lett, 2006 Jan 23. PMID 16412438
    2. Aurora-A mediated histone H3 phosphorylation of threonine 118 controls condensin I and cohesin occupancy in mitosis. Wike CL, et al. Elife, 2016 Feb 16. PMID 26878753, Free PMC Article
    3. Modulation of chromatin boundary activities by nucleosome-remodeling activities in Drosophila melanogaster. Li M, et al. Mol Cell Biol, 2010 Feb. PMID 19995906, Free PMC Article
    4. Transcription in the absence of histone H3.2 and H3K4 methylation. Hödl M, et al. Curr Biol, 2012 Dec 4. PMID 23142044
    5. The RCAF complex mediates chromatin assembly during DNA replication and repair. Tyler JK, et al. Nature, 1999 Dec 2. PMID 10591219

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleosomal DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in nucleosome assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of RCAF complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of nucleosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of nucleosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in polytene chromosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone H3
    Names
    CG33818-PA
    His3:CG33818-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      21459447..21459975
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001032137.2 → NP_001027308.1  histone H3 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001027308.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P02299, Q4ABE4
      Conserved Domains (1) summary
      PTZ00018
      Location:1 → 136
      PTZ00018; histone H3; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    4UUZ_A.1
    6DZT_A.1
    6DZT_E.1
    6PWE_A.1
    6PWE_E.1
    6PWF_A.1
    6PWF_E.1
    P02299.4 P02299

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