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Showing results for peptides AND crispa
Your search for Peltidea AND crispa retrieved no results
Kunitz-Type Peptides from the Sea Anemone Heteractis crispa Demonstrate Potassium Channel Blocking and Anti-Inflammatory Activities.
Gladkikh I, Peigneur S, Sintsova O, Lopes Pinheiro-Junior E, Klimovich A, Menshov A, Kalinovsky A, Isaeva M, Monastyrnaya M, Kozlovskaya E, Tytgat J, Leychenko E. Gladkikh I, et al. Biomedicines. 2020 Nov 4;8(11):473. doi: 10.3390/biomedicines8110473. Biomedicines. 2020. PMID: 33158163 Free PMC article.
The Kunitz/BPTI peptide family includes unique representatives demonstrating various biological activities. Electrophysiological screening of peptides HCRG1 and HCRG2 from the sea anemone Heteractis crispa on six Kv1.x channel isoforms and insect Shaker IR ch …
The Kunitz/BPTI peptide family includes unique representatives demonstrating various biological activities. Electrophysiological scre …
Anxiolytic Effect of Peptides from Sea Anemone Heteractis crispa, Modulators of TRPV1 and ASIC Channels.
Sintsova OV, Kalina RS, Gladkikh IN, Palikova YA, Palikov VA, Borozdina NA, Klimovich AA, Menshov AS, Dyachenko IA, Leychenko EV. Sintsova OV, et al. Dokl Biochem Biophys. 2022 Aug;505(1):145-150. doi: 10.1134/S1607672922040093. Epub 2022 Aug 29. Dokl Biochem Biophys. 2022. PMID: 36038679
This makes their ligands new potential anxiolytic agents. We examined the efficacy of two peptides from the sea anemone Heteractis crispa, Hcr 1b-2 and HCRG21, affecting ASIC1a and TRPV1 channels, respectively, in the open field and elevated plus maze tests. ...
This makes their ligands new potential anxiolytic agents. We examined the efficacy of two peptides from the sea anemone Heteractis …
APETx-Like Peptides from the Sea Anemone Heteractis crispa, Diverse in Their Effect on ASIC1a and ASIC3 Ion Channels.
Kalina RS, Koshelev SG, Zelepuga EA, Kim NY, Kozlov SA, Kozlovskaya EP, Monastyrnaya MM, Gladkikh IN. Kalina RS, et al. Toxins (Basel). 2020 Apr 20;12(4):266. doi: 10.3390/toxins12040266. Toxins (Basel). 2020. PMID: 32326130 Free PMC article.
Currently, five peptide modulators of acid-sensing ion channels (ASICs) attributed to structural class 1b of sea anemone toxins have been described. The APETx2 toxin is the first and most potent ASIC3 inhibitor, so its homologs from sea anemones are known as the APETx-like …
Currently, five peptide modulators of acid-sensing ion channels (ASICs) attributed to structural class 1b of sea anemone toxins have …
New APETx-like peptides from sea anemone Heteractis crispa modulate ASIC1a channels.
Kalina R, Gladkikh I, Dmitrenok P, Chernikov O, Koshelev S, Kvetkina A, Kozlov S, Kozlovskaya E, Monastyrnaya M. Kalina R, et al. Peptides. 2018 Jun;104:41-49. doi: 10.1016/j.peptides.2018.04.013. Epub 2018 Apr 22. Peptides. 2018. PMID: 29684594
Sea anemones are an abundant source of various biologically active peptides. The hydrophobic 20% ethanol fraction of tropical sea anemone Heteractis crispa was shown to contain at least 159 peptide compounds including neurotoxins, proteinase and alpha-amylase …
Sea anemones are an abundant source of various biologically active peptides. The hydrophobic 20% ethanol fraction of tropical sea ane …
Magnoflorine from Tinospora crispa upregulates innate and adaptive immune responses in Balb/c mice.
Ahmad W, Jantan I, Haque MA, Arsyad L. Ahmad W, et al. Int Immunopharmacol. 2022 Oct;111:109081. doi: 10.1016/j.intimp.2022.109081. Epub 2022 Jul 27. Int Immunopharmacol. 2022. PMID: 35907339
However, its effects on the immune responses in animal studies have not been reported. In this study, magnoflorine isolated from Tinospora crispa, at doses of 25, 50 and 100 mg/kg was administered to male Balb/c mice daily for 14 days to evaluate its effect on innate immun …
However, its effects on the immune responses in animal studies have not been reported. In this study, magnoflorine isolated from Tinospora …
Applications of Higenamine in pharmacology and medicine.
Zhang N, Lian Z, Peng X, Li Z, Zhu H. Zhang N, et al. J Ethnopharmacol. 2017 Jan 20;196:242-252. doi: 10.1016/j.jep.2016.12.033. Epub 2016 Dec 19. J Ethnopharmacol. 2017. PMID: 28007527 Review.
RESULTS: In addition to Aconitum, higenamine also exists in many other plants including Tinospora crispa, Nandina domestica T(HUNBERG), Gnetum Parvifolium C.Y. Cheng, sarum Heterotropoides(,)Nelumbo nucifera(,)N.nucifera. ...
RESULTS: In addition to Aconitum, higenamine also exists in many other plants including Tinospora crispa, Nandina domestica T(HUNBERG …
The Significance of Tinospora crispa in Treatment of Diabetes Mellitus.
Thomas A, Rajesh EK, Kumar DS. Thomas A, et al. Phytother Res. 2016 Mar;30(3):357-66. doi: 10.1002/ptr.5559. Epub 2016 Jan 7. Phytother Res. 2016. PMID: 26749336 Review.
Tinospora crispa is a medicinal plant belonging to the botanical family Menispermiaceae. ...Many diterpenes, triterpenes, phytosteroids, alkaloids and their glycosides have been isolated from T. crispa. Cell culture and animal studies suggest that the herb stimulate …
Tinospora crispa is a medicinal plant belonging to the botanical family Menispermiaceae. ...Many diterpenes, triterpenes, phytosteroi …
Crispenes F and G, cis-Clerodane Furanoditerpenoids from Tinospora crispa, Inhibit STAT3 Dimerization.
Noman MAA, Hossain T, Ahsan M, Jamshidi S, Hasan CM, Rahman KM. Noman MAA, et al. J Nat Prod. 2018 Feb 23;81(2):236-242. doi: 10.1021/acs.jnatprod.7b00377. Epub 2018 Feb 3. J Nat Prod. 2018. PMID: 29397715
Two new cis-clerodane-type furanoditerpenes, crispenes F and G (1 and 2), together with seven known compounds, were isolated from the stems of Tinospora crispa. Crispenes F and G (1 and 2) inhibited STAT3 dimerization in a cell-free fluorescent polarization assay and were …
Two new cis-clerodane-type furanoditerpenes, crispenes F and G (1 and 2), together with seven known compounds, were isolated from the stems …
Immunomodulatory effects of Tinospora crispa extract and its major compounds on the immune functions of RAW 264.7 macrophages.
Ahmad W, Jantan I, Kumolosasi E, Haque MA, Bukhari SNA. Ahmad W, et al. Int Immunopharmacol. 2018 Jul;60:141-151. doi: 10.1016/j.intimp.2018.04.046. Epub 2018 May 3. Int Immunopharmacol. 2018. PMID: 29730557
The in vivo immunomodulatory activities of Tinospora crispa have been reported but its molecular mechanisms underlying its immunomodulatory properties remains obscure and the active constituents contributing to the activities have not been identified. The present study was …
The in vivo immunomodulatory activities of Tinospora crispa have been reported but its molecular mechanisms underlying its immunomodu …
Network pharmacology integrated molecular dynamics reveals the bioactive compounds and potential targets of Tinospora crispa Linn. as insulin sensitizer.
Zuhri UM, Purwaningsih EH, Fadilah F, Yuliana ND. Zuhri UM, et al. PLoS One. 2022 Jun 23;17(6):e0251837. doi: 10.1371/journal.pone.0251837. eCollection 2022. PLoS One. 2022. PMID: 35737707 Free PMC article.
Tinoscorside A, Makisterone C, Borapetoside A and B, and beta sitosterol consider the main phytoconstituents of Tinospora crispa by its binding with active sites of main protein targets of insulin resistance potential therapy. ...Regulation in glucose homeostasis, adipolys …
Tinoscorside A, Makisterone C, Borapetoside A and B, and beta sitosterol consider the main phytoconstituents of Tinospora crispa by i …
91 results