Anxiolytic Effect of Peptides from Sea Anemone Heteractis crispa, Modulators of TRPV1 and ASIC Channels.
Sintsova OV, Kalina RS, Gladkikh IN, Palikova YA, Palikov VA, Borozdina NA, Klimovich AA, Menshov AS, Dyachenko IA, Leychenko EV.
Sintsova OV, et al.
Dokl Biochem Biophys. 2022 Aug;505(1):145-150. doi: 10.1134/S1607672922040093. Epub 2022 Aug 29.
Dokl Biochem Biophys. 2022.
PMID: 36038679
This makes their ligands new potential anxiolytic agents. We examined the efficacy of two peptides from the sea anemone Heteractis crispa, Hcr 1b-2 and HCRG21, affecting ASIC1a and TRPV1 channels, respectively, in the open field and elevated plus maze tests. ...
This makes their ligands new potential anxiolytic agents. We examined the efficacy of two peptides from the sea anemone Heteractis …