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Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD.
Neurobiol Dis. 2023 Apr;179:106050. doi: 10.1016/j.nbd.2023.106050. Epub 2023 Feb 20.
Neurobiol Dis. 2023.
PMID: 36809847
Free article.
Modeling Alzheimer's disease related phenotypes in the Ts65Dn mouse: impact of age on Aβ, Tau, pTau, NfL, and behavior.
Overk C, Fiorini E, Babolin C, Vukicevic M, Morici C, Madani R, Eligert V, Kosco-Vilbois M, Roberts A, Becker A, Pfeifer A, Mobley WC.
Overk C, et al. Among authors: eligert v.
Front Neurosci. 2023 Jun 28;17:1202208. doi: 10.3389/fnins.2023.1202208. eCollection 2023.
Front Neurosci. 2023.
PMID: 37449271
Free PMC article.
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The role of γ-secretase activating protein (GSAP) and imatinib in the regulation of γ-secretase activity and amyloid-β generation.
Hussain I, Fabrègue J, Anderes L, Ousson S, Borlat F, Eligert V, Berger S, Dimitrov M, Alattia JR, Fraering PC, Beher D.
Hussain I, et al. Among authors: eligert v.
J Biol Chem. 2013 Jan 25;288(4):2521-31. doi: 10.1074/jbc.M112.370924. Epub 2012 Dec 3.
J Biol Chem. 2013.
PMID: 23209290
Free PMC article.
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Pharmacophore-based design of novel oxadiazoles as selective sphingosine-1-phosphate (S1P) receptor agonists with in vivo efficacy.
Quattropani A, Sauer WH, Crosignani S, Dorbais J, Gerber P, Gonzalez J, Marin D, Muzerelle M, Beltran F, Nichols A, Georgi K, Schneider M, Vitte PA, Eligert V, Novo-Perez L, Hantson J, Nock S, Carboni S, de Souza AL, Arrighi JF, Boschert U, Bombrun A.
Quattropani A, et al. Among authors: eligert v.
ChemMedChem. 2015 Apr;10(4):688-714. doi: 10.1002/cmdc.201402557. Epub 2015 Mar 3.
ChemMedChem. 2015.
PMID: 25735812
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Discovery of a novel series of potent S1P1 agonists.
Crosignani S, Bombrun A, Covini D, Maio M, Marin D, Quattropani A, Swinnen D, Simpson D, Sauer W, Françon B, Martin T, Cambet Y, Nichols A, Martinou I, Burgat-Charvillon F, Rivron D, Donini C, Schott O, Eligert V, Novo-Perez L, Vitte PA, Arrighi JF.
Crosignani S, et al. Among authors: eligert v.
Bioorg Med Chem Lett. 2010 Mar 1;20(5):1516-9. doi: 10.1016/j.bmcl.2010.01.102. Epub 2010 Jan 25.
Bioorg Med Chem Lett. 2010.
PMID: 20149651
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