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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 2
1966 4
1969 3
1970 1
1971 3
1972 3
1973 6
1974 7
1975 19
1976 16
1977 22
1978 12
1979 21
1980 29
1981 17
1982 27
1983 39
1984 44
1985 49
1986 60
1987 54
1988 66
1989 80
1990 57
1991 89
1992 74
1993 82
1994 92
1995 85
1996 91
1997 107
1998 122
1999 120
2000 134
2001 145
2002 140
2003 155
2004 156
2005 172
2006 206
2007 209
2008 208
2009 212
2010 260
2011 279
2012 282
2013 262
2014 270
2015 261
2016 245
2017 229
2018 227
2019 221
2020 201
2021 224
2022 186
2023 135
2024 47

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Search Results

6,093 results

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Page 1
Identification of genes that are associated with DNA repeats in prokaryotes.
Jansen R, Embden JD, Gaastra W, Schouls LM. Jansen R, et al. Mol Microbiol. 2002 Mar;43(6):1565-75. doi: 10.1046/j.1365-2958.2002.02839.x. Mol Microbiol. 2002. PMID: 11952905 Free article.
The cas genes were invariably located adjacent to a CRISPR locus, indicating that the cas genes and CRISPR loci have a functional relationship. The cas3 gene showed motifs characteristic for helicases of the superfamily 2, and the cas4 gene showed motifs of t …
The cas genes were invariably located adjacent to a CRISPR locus, indicating that the cas genes and CRISPR loci have a …
Phase-variable bacterial loci: how bacteria gamble to maximise fitness in changing environments.
Phillips ZN, Tram G, Seib KL, Atack JM. Phillips ZN, et al. Biochem Soc Trans. 2019 Aug 30;47(4):1131-1141. doi: 10.1042/BST20180633. Epub 2019 Jul 24. Biochem Soc Trans. 2019. PMID: 31341035 Review.
Switching of expression can be achieved by a number of different mechanisms. Phase-variable genes typically encode bacterial surface structures, such as adhesins, pili, and lipooligosaccharide, and provide an extra contingency strategy in small-genome pathogens that …
Switching of expression can be achieved by a number of different mechanisms. Phase-variable genes typically encode bacterial s …
Bacterial contingency loci: the role of simple sequence DNA repeats in bacterial adaptation.
Moxon R, Bayliss C, Hood D. Moxon R, et al. Annu Rev Genet. 2006;40:307-33. doi: 10.1146/annurev.genet.40.110405.090442. Annu Rev Genet. 2006. PMID: 17094739 Review.
Bacterial adaptation to their hosts involves either a mechanism for sensing and responding to external changes or the selection of variants that arise through mutation. ...These SSRs are located within the reading frame or in the promoter of a subset of genes, often
Bacterial adaptation to their hosts involves either a mechanism for sensing and responding to external changes or the selection of va
Systematic prediction of functionally linked genes in bacterial and archaeal genomes.
Shmakov SA, Faure G, Makarova KS, Wolf YI, Severinov KV, Koonin EV. Shmakov SA, et al. Nat Protoc. 2019 Oct;14(10):3013-3031. doi: 10.1038/s41596-019-0211-1. Epub 2019 Sep 13. Nat Protoc. 2019. PMID: 31520072 Free PMC article.
Functionally linked genes in bacterial and archaeal genomes are often organized into operons. ...We exemplify the performance of the protocol with three test cases, namely, genes linked to CRISPR-Cas systems using the 'CRISPRicity' metric, genes associ …
Functionally linked genes in bacterial and archaeal genomes are often organized into operons. ...We exemplify the performance …
Genes for the cytoskeletal protein tubulin in the bacterial genus Prosthecobacter.
Jenkins C, Samudrala R, Anderson I, Hedlund BP, Petroni G, Michailova N, Pinel N, Overbeek R, Rosati G, Staley JT. Jenkins C, et al. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):17049-54. doi: 10.1073/pnas.012516899. Epub 2002 Dec 16. Proc Natl Acad Sci U S A. 2002. PMID: 12486237 Free PMC article.
Tubulins, the protein constituents of the microtubule cytoskeleton, are present in all known eukaryotes but have never been found in the Bacteria or Archaea. Here we report the presence of two tubulin-like genes [bacterial tubulin a (btuba) and bacterial tubu …
Tubulins, the protein constituents of the microtubule cytoskeleton, are present in all known eukaryotes but have never been found in the Bac …
Bacterial mercury resistance from atoms to ecosystems.
Barkay T, Miller SM, Summers AO. Barkay T, et al. FEMS Microbiol Rev. 2003 Jun;27(2-3):355-84. doi: 10.1016/S0168-6445(03)00046-9. FEMS Microbiol Rev. 2003. PMID: 12829275 Free article. Review.
Bacterial resistance to inorganic and organic mercury compounds (HgR) is one of the most widely observed phenotypes in eubacteria. ...Genes conferring HgR occur on chromosomes, plasmids, and transposons and their operon arrangements can be quite diverse, frequently
Bacterial resistance to inorganic and organic mercury compounds (HgR) is one of the most widely observed phenotypes in eubacteria. ..
How to become a pathogen.
Groisman EA, Ochman H. Groisman EA, et al. Trends Microbiol. 1994 Aug;2(8):289-94. doi: 10.1016/0966-842x(94)90006-x. Trends Microbiol. 1994. PMID: 7981972
For most bacterial species, virulence is viewed as a derived state, whereby pathogens acquire certain loci and are rendered virulent. The majority of virulence genes in Salmonella are present in closely related nonpathogenic species, and most genes kno …
For most bacterial species, virulence is viewed as a derived state, whereby pathogens acquire certain loci and are rendered vi …
Plasmid-mediated virulence genes in non-typhoid Salmonella serovars.
Guiney DG, Fang FC, Krause M, Libby S. Guiney DG, et al. FEMS Microbiol Lett. 1994 Nov 15;124(1):1-9. doi: 10.1111/j.1574-6968.1994.tb07253.x. FEMS Microbiol Lett. 1994. PMID: 8001760 Review.
Additional plasmid genes encode complement resistance including the rck locus which is homologous to ail from Yersinia. Rck blocks formation of the complement membrane attack complex on the bacterial surface. Several loci involved in plasmid replication and s …
Additional plasmid genes encode complement resistance including the rck locus which is homologous to ail from Yersinia. Rck blocks fo …
Co-resistance: an opportunity for the bacteria and resistance genes.
Cantón R, Ruiz-Garbajosa P. Cantón R, et al. Curr Opin Pharmacol. 2011 Oct;11(5):477-85. doi: 10.1016/j.coph.2011.07.007. Epub 2011 Aug 11. Curr Opin Pharmacol. 2011. PMID: 21840259 Review.
Co-resistance involves transfer of several genes into the same bacteria and/or the acquisition of mutations in different genetic loci affecting different antimicrobials whereas pleiotropic resistance implies the same genetic event affecting several antimicrobials. . …
Co-resistance involves transfer of several genes into the same bacteria and/or the acquisition of mutations in different genetic l
Ranking essential bacterial processes by speed of mutant death.
Gallagher LA, Bailey J, Manoil C. Gallagher LA, et al. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):18010-18017. doi: 10.1073/pnas.2001507117. Epub 2020 Jul 14. Proc Natl Acad Sci U S A. 2020. PMID: 32665440 Free PMC article.
Since essential genes control the most fundamental processes of bacterial life, this is a glaring deficiency. To address this limitation, we developed a procedure for transposon insertion mutant sequencing that includes essential genes. The method, called tra …
Since essential genes control the most fundamental processes of bacterial life, this is a glaring deficiency. To address this …
6,093 results