RecName: Full=Hypoxia-inducible factor 1-alpha; Short=HIF-1-alpha; Sho - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

HIF-1α Mediates Immunosuppression and Chemoresistance in Colorectal Cancer by Inhibiting CXCL9, -10 and -11. [Biomed Pharmacother. 2024]
HIF-1α Mediates Immunosuppression and Chemoresistance in Colorectal Cancer by Inhibiting CXCL9, -10 and -11.
Su Y, Liu J, Tian Y, Dong H, Shi M, Zhang J, Li W, Huang Q, Xiang N, Wang C, et al. Biomed Pharmacother. 2024 Apr; 173:116427. Epub 2024 Mar 13.
Single-Cell RNA Sequencing Reveals HIF1A as a Severity-Sensitive Immunological Scar in Circulating Monocytes of Convalescent Comorbidity-Free COVID-19 Patients. [Cells. 2024]
Single-Cell RNA Sequencing Reveals HIF1A as a Severity-Sensitive Immunological Scar in Circulating Monocytes of Convalescent Comorbidity-Free COVID-19 Patients.
May L, Chu CF, Zielinski CE. Cells. 2024 Feb 6; 13(4). Epub 2024 Feb 6.
The Regulatory Mechanism of Hypoxia-inducible Factor 1 and its Clinical Significance. [Curr Mol Pharmacol. 2024]
The Regulatory Mechanism of Hypoxia-inducible Factor 1 and its Clinical Significance.
Yin CL, Ma YJ. Curr Mol Pharmacol. 2024; 17:e18761429266116.

RefSeq genomic sequence
See the genomic reference sequence for the HIF1A gene (NG_029606.1).
RefSeq protein isoforms
See 3 reference sequence protein isoforms for the HIF1A gene.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioAssay by Target (Summary)
BioAssay by Target (Summary)
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures
Related Structures (Summary)
Related structures

Q16665 [Domain Mapping of Disease Mut...]
Q16665
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Hypoxia-inducible factor 1-alpha; Short=HIF-1-alpha; Short=HIF1-al...
RecName: Full=Hypoxia-inducible factor 1-alpha; Short=HIF-1-alpha; Short=HIF1-alpha; AltName: Full=ARNT-interacting protein; AltName: Full=Basic-helix-loop-helix-PAS protein MOP1; AltName: Full=Class E basic helix-loop-helix protein 78; Short=bHLHe78; AltName: Full=Member of PAS protein 1; AltName: Full=PAS domain-containing protein 8
gi|2498017|sp|Q16665.1|HIF1A_HUMAN

Protein

Your browsing activity is empty.

Activity recording is turned off.

Protein