Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1981 1
1983 1
1987 1
1997 1
2000 3
2001 7
2002 30
2003 41
2004 69
2005 95
2006 115
2007 126
2008 128
2009 179
2010 170
2011 190
2012 198
2013 229
2014 260
2015 261
2016 268
2017 268
2018 271
2019 267
2020 235
2021 244
2022 254
2023 227
2024 74

Text availability

Article attribute

Article type

Publication date

Search Results

3,729 results

Results by year

Filters applied: . Clear all
Page 1
T-bet(+) B cells accumulate in adipose tissue and exacerbate metabolic disorder during obesity.
Hägglöf T, Vanz C, Kumagai A, Dudley E, Ortega V, Siller M, Parthasarathy R, Keegan J, Koenigs A, Shute T, Leadbetter EA. Hägglöf T, et al. Cell Metab. 2022 Aug 2;34(8):1121-1136.e6. doi: 10.1016/j.cmet.2022.07.002. Epub 2022 Jul 21. Cell Metab. 2022. PMID: 35868310 Free PMC article.
Furthermore, transfer of serum or purified IgG from HFD mice restores metabolic disease in T-bet(+) B cell-deficient mice, confirming T-bet(+) B cell-derived IgG as a key mediator of inflammation during obesity. Together, these findings reveal an impor …
Furthermore, transfer of serum or purified IgG from HFD mice restores metabolic disease in T-bet(+) B cell-deficient mice, con …
Stability and function of regulatory T cells expressing the transcription factor T-bet.
Levine AG, Mendoza A, Hemmers S, Moltedo B, Niec RE, Schizas M, Hoyos BE, Putintseva EV, Chaudhry A, Dikiy S, Fujisawa S, Chudakov DM, Treuting PM, Rudensky AY. Levine AG, et al. Nature. 2017 Jun 15;546(7658):421-425. doi: 10.1038/nature22360. Epub 2017 Jun 7. Nature. 2017. PMID: 28607488 Free PMC article.
Loss of function or elimination of T-bet-expressing T(reg) cells-but not of T-bet expression in T(reg) cells-resulted in severe T(H)1 autoimmunity. Conversely, following depletion of T-bet(-) T(reg) cells, the remaining T-bet …
Loss of function or elimination of T-bet-expressing T(reg) cells-but not of T-bet expression in T(reg) cells-res …
A novel transcription factor, T-bet, directs Th1 lineage commitment.
Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. Szabo SJ, et al. Cell. 2000 Mar 17;100(6):655-69. doi: 10.1016/s0092-8674(00)80702-3. Cell. 2000. PMID: 10761931 Free article.
T-bet expression correlates with IFNgamma expression in Th1 and NK cells. Ectopic expression of T-bet both transactivates the IFNgamma gene and induces endogenous IFNgamma production. ...
T-bet expression correlates with IFNgamma expression in Th1 and NK cells. Ectopic expression of T-bet both trans …
T-bet in disease.
Lazarevic V, Glimcher LH. Lazarevic V, et al. Nat Immunol. 2011 Jun 20;12(7):597-606. doi: 10.1038/ni.2059. Nat Immunol. 2011. PMID: 21685955 Free PMC article. Review.
At the center of the type 1 inflammatory response is the transcription factor T-bet, a critical regulator of the T(H)1 differentiation program. T-bet induces the production of interferon-gamma (IFN-gamma) and orchestrates the T(H)1 cell-migratory progr …
At the center of the type 1 inflammatory response is the transcription factor T-bet, a critical regulator of the T(H)1 differe …
A transcriptionally distinct subset of influenza-specific effector memory B cells predicts long-lived antibody responses to vaccination in humans.
Nellore A, Zumaquero E, Scharer CD, Fucile CF, Tipton CM, King RG, Mi T, Mousseau B, Bradley JE, Zhou F, Mutneja S, Goepfert PA, Boss JM, Randall TD, Sanz I, Rosenberg AF, Lund FE. Nellore A, et al. Immunity. 2023 Apr 11;56(4):847-863.e8. doi: 10.1016/j.immuni.2023.03.001. Epub 2023 Mar 22. Immunity. 2023. PMID: 36958335 Free PMC article.
We found that HA-specific human Bmem cells differed in the expression of surface marker FcRL5 and transcriptional factor T-bet. FcRL5(+)T-bet(+) Bmem cells were transcriptionally similar to effector-like memory cells, while T-bet(neg)FcRL …
We found that HA-specific human Bmem cells differed in the expression of surface marker FcRL5 and transcriptional factor T-bet …
T-BET and EOMES sustain mature human NK cell identity and antitumor function.
Wong P, Foltz JA, Chang L, Neal CC, Yao T, Cubitt CC, Tran J, Kersting-Schadek S, Palakurty S, Jaeger N, Russler-Germain DA, Marin ND, Gang M, Wagner JA, Zhou AY, Jacobs MT, Foster M, Schappe T, Marsala L, McClain E, Pence P, Becker-Hapak M, Fisk B, Petti AA, Griffith OL, Griffith M, Berrien-Elliott MM, Fehniger TA. Wong P, et al. J Clin Invest. 2023 Jul 3;133(13):e162530. doi: 10.1172/JCI162530. J Clin Invest. 2023. PMID: 37279078 Free PMC article.
To address this, T-BET and EOMES were deleted in unexpanded primary human NK cells using CRISPR/Cas9. ...NK cells lacking T-BET and EOMES also exhibited defective responses to cytokine stimulation. ...
To address this, T-BET and EOMES were deleted in unexpanded primary human NK cells using CRISPR/Cas9. ...NK cells lacking T …
The evolving role of T-bet in resistance to infection.
Pritchard GH, Kedl RM, Hunter CA. Pritchard GH, et al. Nat Rev Immunol. 2019 Jun;19(6):398-410. doi: 10.1038/s41577-019-0145-4. Nat Rev Immunol. 2019. PMID: 30846856 Free PMC article. Review.
The identification of T-bet as a key transcription factor associated with the development of IFNgamma-producing CD4(+) T cells predicted a crucial role for T-bet in cell-mediated immunity and in resistance to many intracellular infections. ...This arti …
The identification of T-bet as a key transcription factor associated with the development of IFNgamma-producing CD4(+) T cells …
T-bet(+) memory B cells: Generation, function, and fate.
Knox JJ, Myles A, Cancro MP. Knox JJ, et al. Immunol Rev. 2019 Mar;288(1):149-160. doi: 10.1111/imr.12736. Immunol Rev. 2019. PMID: 30874358 Free PMC article. Review.
B cells expressing the transcription factor T-bet have emerged as participants in a number of protective and pathogenic immune responses. ...Despite recent advances, a number of questions remain regarding the basic biology of T-bet(+) B cells and their …
B cells expressing the transcription factor T-bet have emerged as participants in a number of protective and pathogenic immune …
T-bet-expressing B cells during HIV and HCV infections.
Knox JJ, Kaplan DE, Betts MR. Knox JJ, et al. Cell Immunol. 2017 Nov;321:26-34. doi: 10.1016/j.cellimm.2017.04.012. Epub 2017 Jul 11. Cell Immunol. 2017. PMID: 28739077 Free PMC article. Review.
T-bet-expressing B cells, first identified as perpetuators of autoimmunity, were recently shown to be critical for murine antiviral responses. ...In this review, we discuss the induction of T-bet in B cells following both HIV and HCV infections, the fa …
T-bet-expressing B cells, first identified as perpetuators of autoimmunity, were recently shown to be critical for murine anti …
T-bet as a key regulator of mucosal immunity.
Mohamed R, Lord GM. Mohamed R, et al. Immunology. 2016 Apr;147(4):367-76. doi: 10.1111/imm.12575. Epub 2016 Feb 23. Immunology. 2016. PMID: 26726991 Free PMC article. Review.
Initially understood to be a key regulator of interferon-gamma-producing helper T cells, our knowledge of T-bet's functional roles has expanded to encompass a growing range of cellular lineages. ...With the increasingly diverse effects of T-bet on diff …
Initially understood to be a key regulator of interferon-gamma-producing helper T cells, our knowledge of T-bet's functional r …
3,729 results