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    Results: 1 to 20 of 140

    1.

    The relationship between thiopurine methyltransferase activity and genotype in blasts from patients with acute leukemia.

    Coulthard SA, Howell C, Robson J, Hall AG.

    Blood. 1998 Oct 15;92(8):2856-62.PMID: 9763570 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    [Relationship between single nucleotide polymorphisms in thiopurine methyltransferase gene and tolerance to thiopurines in acute leukemia]

    Ma XL, Zhu P, Wu MY, Li ZG, Hu YM.

    Zhonghua Er Ke Za Zhi. 2003 Dec;41(12):929-33. Chinese. PMID: 14723818 [PubMed - indexed for MEDLINE]Related articles

    3.

    Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia.

    McLeod HL, Krynetski EY, Relling MV, Evans WE.

    Leukemia. 2000 Apr;14(4):567-72. Review.PMID: 10764140 [PubMed - indexed for MEDLINE]Related articles

    4.

    Polymorphic thiopurine methyltransferase in erythrocytes is indicative of activity in leukemic blasts from children with acute lymphoblastic leukemia.

    McLeod HL, Relling MV, Liu Q, Pui CH, Evans WE.

    Blood. 1995 Apr 1;85(7):1897-902.PMID: 7703493 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus.

    Relling MV, Hancock ML, Rivera GK, Sandlund JT, Ribeiro RC, Krynetski EY, Pui CH, Evans WE.

    J Natl Cancer Inst. 1999 Dec 1;91(23):2001-8.PMID: 10580024 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Possible implication of thiopurine S-methyltransferase in occurrence of infectious episodes during maintenance therapy for childhood lymphoblastic leukemia with mercaptopurine.

    Dervieux T, Médard Y, Verpillat P, Guigonis V, Duval M, Lescoeur B, Suciu S, Vilmer E, Jacqz-Aigrain E.

    Leukemia. 2001 Nov;15(11):1706-12.PMID: 11681411 [PubMed - indexed for MEDLINE]Related articles

    7.

    Thiopurine methyltransferase activity is related to the risk of relapse of childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study.

    Schmiegelow K, Forestier E, Kristinsson J, Söderhäll S, Vettenranta K, Weinshilboum R, Wesenberg F; Nordic Society of Paediatric Haematology and Oncology.

    Leukemia. 2009 Mar;23(3):557-64. Epub 2008 Nov 6.PMID: 18987654 [PubMed - indexed for MEDLINE]Related articles

    8.

    Thiopurine methyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia.

    Stanulla M, Schaeffeler E, Flohr T, Cario G, Schrauder A, Zimmermann M, Welte K, Ludwig WD, Bartram CR, Zanger UM, Eichelbaum M, Schrappe M, Schwab M.

    JAMA. 2005 Mar 23;293(12):1485-9.PMID: 15784872 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine.

    Evans WE, Hon YY, Bomgaars L, Coutre S, Holdsworth M, Janco R, Kalwinsky D, Keller F, Khatib Z, Margolin J, Murray J, Quinn J, Ravindranath Y, Ritchey K, Roberts W, Rogers ZR, Schiff D, Steuber C, Tucci F, Kornegay N, Krynetski EY, Relling MV.

    J Clin Oncol. 2001 Apr 15;19(8):2293-301.PMID: 11304783 [PubMed - indexed for MEDLINE]Related articles

    10.

    Should TPMT genotype and activity be used to monitor 6-mercaptopurine treatment in children with acute lymphoblastic leukaemia?

    Fakhoury M, Andreu-Gallien J, Mahr A, Medard Y, Azougagh S, Vilmer E, Jacqz-Aigrain E.

    J Clin Pharm Ther. 2007 Dec;32(6):633-9.PMID: 18021342 [PubMed - indexed for MEDLINE]Related articles

    11.

    The low frequency of defective TPMT alleles in Turkish population: a study on pediatric patients with acute lymphoblastic leukemia.

    Tumer TB, Ulusoy G, Adali O, Sahin G, Gozdasoglu S, Arinç E.

    Am J Hematol. 2007 Oct;82(10):906-10.PMID: 17617792 [PubMed - indexed for MEDLINE]Related articles

    12.

    [Relationships between thiopurine methyltransferase gene polymorphisms and its enzymatic activity]

    Ma XL, Wu MY, Hu YM, Zu P, Li ZG.

    Zhonghua Zhong Liu Za Zhi. 2006 Jun;28(6):456-9. Chinese. PMID: 17152495 [PubMed - indexed for MEDLINE]Related articles

    13.

    Analysis of thiopurine S-methyltransferase polymorphism in the population of Serbia and Montenegro and mercaptopurine therapy tolerance in childhood acute lymphoblastic leukemia.

    Dokmanovic L, Urosevic J, Janic D, Jovanovic N, Petrucev B, Tosic N, Pavlovic S.

    Ther Drug Monit. 2006 Dec;28(6):800-6.PMID: 17164697 [PubMed - indexed for MEDLINE]Related articles

    14.

    [Significance of TPMT activity and TGNs level detection for individualizing 6-mercaptopurine chemotherapy]

    Gu LJ, Ye QD, Liang AB, Zhao JC, Xue HL, Tang YN, Chen J, Ye YC.

    Zhonghua Xue Ye Xue Za Zhi. 2003 Jan;24(1):18-21. Chinese. PMID: 12679004 [PubMed - indexed for MEDLINE]Related articles

    15.

    Thiopurine S-methyltransferase (TPMT) gene polymorphism in Brazilian children with acute lymphoblastic leukemia: association with clinical and laboratory data.

    Silva MR, de Oliveira BM, Viana MB, Murao M, Romanha AJ.

    Ther Drug Monit. 2008 Dec;30(6):700-4.PMID: 19057372 [PubMed - indexed for MEDLINE]Related articles

    16.

    A comparison of molecular and enzyme-based assays for the detection of thiopurine methyltransferase mutations.

    Coulthard SA, Rabello C, Robson J, Howell C, Minto L, Middleton PG, Gandhi MK, Jackson G, McLelland J, O'Brien H, Smith S, Reid MM, Pearson AD, Hall AG.

    Br J Haematol. 2000 Sep;110(3):599-604.PMID: 10997970 [PubMed - indexed for MEDLINE]Related articles

    17.

    Thiopurine methyltransferase: a review and a clinical pilot study.

    Keuzenkamp-Jansen CW, Leegwater PA, De Abreu RA, Lambooy MA, Bokkerink JP, Trijbels JM.

    J Chromatogr B Biomed Appl. 1996 Mar 29;678(1):15-22. Review.PMID: 8861653 [PubMed - indexed for MEDLINE]Related articles

    18.

    The thiopurine methyltransferase genetic polymorphism is associated with thioguanine-related veno-occlusive disease of the liver in children with acute lymphoblastic leukemia.

    Lennard L, Richards S, Cartwright CS, Mitchell C, Lilleyman JS, Vora A; UK MRC/NCRI Childhood Leukaemia Working Party.

    Clin Pharmacol Ther. 2006 Oct;80(4):375-83.PMID: 17015055 [PubMed - indexed for MEDLINE]Related articles

    19.

    Genotyping of thiopurine methyltransferase in patients with acute leukemia using LightCycler PCR.

    Davison JE, McMullin MF, Catherwood MA.

    Leuk Lymphoma. 2006 Aug;47(8):1624-8.PMID: 16966276 [PubMed - indexed for MEDLINE]Related articles

    20.

    Effect of methotrexate polyglutamates on thioguanine nucleotide concentrations during continuation therapy of acute lymphoblastic leukemia with mercaptopurine.

    Dervieux T, Hancock M, Evans W, Pui CH, Relling MV.

    Leukemia. 2002 Feb;16(2):209-12.PMID: 11840287 [PubMed - indexed for MEDLINE]Related articlesFree article

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