PubMed

Mechanisms of sulfonylurea's stimulation of insulin secretion in vivo: selective amplification of insulin secretory burst mass.

Pørksen NK, Munn SR, Steers JL, Schmitz O, Veldhuis JD, Butler PC.

Diabetes. 1996 Dec;45(12):1792-7.PMID: 8922367 [PubMed - indexed for MEDLINE]Related articles

Effects of glucose ingestion versus infusion on pulsatile insulin secretion. The incretin effect is achieved by amplification of insulin secretory burst mass.

Pørksen N, Munn S, Steers J, Veldhuis JD, Butler PC.

Diabetes. 1996 Oct;45(10):1317-23.PMID: 8826965 [PubMed - indexed for MEDLINE]Related articles

Effects of somatostatin on pulsatile insulin secretion: elective inhibition of insulin burst mass.

Pørksen N, Munn SR, Steers JL, Veldhuis JD, Butler PC.

Am J Physiol. 1996 Jun;270(6 Pt 1):E1043-9.PMID: 8764190 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide 1 increases mass but not frequency or orderliness of pulsatile insulin secretion.

Pørksen N, Grøfte B, Nyholm B, Holst JJ, Pincus SM, Veldhuis JD, Schmitz O, Butler PC.

Diabetes. 1998 Jan;47(1):45-9.PMID: 9421373 [PubMed - indexed for MEDLINE]Related articles

Human insulin release processes measured by intraportal sampling.

Pørksen N, Grøfte T, Greisen J, Mengel A, Juhl C, Veldhuis JD, Schmitz O, Rössle M, Vilstrup H.

Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E695-702.PMID: 11832375 [PubMed - indexed for MEDLINE]Related articlesFree article

Repaglinide acutely amplifies pulsatile insulin secretion by augmentation of burst mass with no effect on burst frequency.

Juhl CB, Pørksen N, Hollingdal M, Sturis J, Pincus S, Veldhuis JD, Dejgaard A, Schmitz O.

Diabetes Care. 2000 May;23(5):675-81.PMID: 10834429 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute and short-term administration of a sulfonylurea (gliclazide) increases pulsatile insulin secretion in type 2 diabetes.

Juhl CB, Pørksen N, Pincus SM, Hansen AP, Veldhuis JD, Schmitz O.

Diabetes. 2001 Aug;50(8):1778-84.PMID: 11473038 [PubMed - indexed for MEDLINE]Related articlesFree article

Pulsatile insulin secretion dictates systemic insulin delivery by regulating hepatic insulin extraction in humans.

Meier JJ, Veldhuis JD, Butler PC.

Diabetes. 2005 Jun;54(6):1649-56.PMID: 15919785 [PubMed - indexed for MEDLINE]Related articlesFree article

A new method for comparing portal and peripheral venous insulin delivery in humans: tolbutamide versus insulin infusion.

Lewis GF, Steiner G, Polonsky KS, Weller B, Zinman B.

J Clin Endocrinol Metab. 1994 Jul;79(1):66-70.PMID: 8027255 [PubMed - indexed for MEDLINE]Related articles

Hepatic glucose production is regulated both by direct hepatic and extrahepatic effects of insulin in humans.

Lewis GF, Zinman B, Groenewoud Y, Vranic M, Giacca A.

Diabetes. 1996 Apr;45(4):454-62.PMID: 8603767 [PubMed - indexed for MEDLINE]Related articles

Decrease in beta-cell mass leads to impaired pulsatile insulin secretion, reduced postprandial hepatic insulin clearance, and relative hyperglucagonemia in the minipig.

Kjems LL, Kirby BM, Welsh EM, Veldhuis JD, Straume M, McIntyre SS, Yang D, Lefèbvre P, Butler PC.

Diabetes. 2001 Sep;50(9):2001-12.PMID: 11522665 [PubMed - indexed for MEDLINE]Related articlesFree article

Tripartite neuroendocrine activation of the human growth hormone (GH) axis in women by continuous 24-hour GH-releasing peptide infusion: pulsatile, entropic, and nyctohemeral mechanisms.

Shah N, Evans WS, Bowers CY, Veldhuis JD.

J Clin Endocrinol Metab. 1999 Jun;84(6):2140-50.PMID: 10372723 [PubMed - indexed for MEDLINE]Related articlesFree article

IGF-I inhibits burst mass of pulsatile insulin secretion at supraphysiological and low IGF-I infusion rates.

Pørksen N, Hussain MA, Bianda TL, Nyholm B, Christiansen JS, Butler PC, Veldhuis JD, Froesch ER, Schmitz O.

Am J Physiol. 1997 Mar;272(3 Pt 1):E352-8.PMID: 9124538 [PubMed - indexed for MEDLINE]Related articles

Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects.

Polonsky KS, Given BD, Van Cauter E.

J Clin Invest. 1988 Feb;81(2):442-8.PMID: 3276730 [PubMed - indexed for MEDLINE]Related articlesFree article

The conscious Göttingen minipig as a model for studying rapid pulsatile insulin secretion in vivo.

Larsen MO, Elander M, Sturis J, Wilken M, Carr RD, Rolin B, Pørksen N.

Diabetologia. 2002 Oct;45(10):1389-96. Epub 2002 Sep 5.PMID: 12378379 [PubMed - indexed for MEDLINE]Related articles

Basal hepatic glucose production is regulated by the portal vein insulin concentration.

Sindelar DK, Chu CA, Venson P, Donahue EP, Neal DW, Cherrington AD.

Diabetes. 1998 Apr;47(4):523-9.PMID: 9568682 [PubMed - indexed for MEDLINE]Related articlesFree article

Repaglinide treatment amplifies first-phase insulin secretion and high-frequency pulsatile insulin release in Type 2 diabetes.

Hollingdal M, Sturis J, Gall MA, Damsbo P, Pincus S, Veldhuis JD, Pørksen N, Schmitz O, Juhl CB.

Diabet Med. 2005 Oct;22(10):1408-13.PMID: 16176204 [PubMed - indexed for MEDLINE]Related articles

Short-term treatment with GLP-1 increases pulsatile insulin secretion in Type II diabetes with no effect on orderliness.

Juhl CB, Schmitz O, Pincus S, Holst JJ, Veldhuis J, Pørksen N.

Diabetologia. 2000 May;43(5):583-8.PMID: 10855533 [PubMed - indexed for MEDLINE]Related articles

Impact of sampling technique on appraisal of pulsatile insulin secretion by deconvolution and cluster analysis.

Pørksen N, Munn S, Steers J, Veldhuis JD, Butler PC.

Am J Physiol. 1995 Dec;269(6 Pt 1):E1106-14.PMID: 8572204 [PubMed - indexed for MEDLINE]Related articles

Measurement of pulsatile insulin secretion in the rat: direct sampling from the hepatic portal vein.

Matveyenko AV, Veldhuis JD, Butler PC.

Am J Physiol Endocrinol Metab. 2008 Sep;295(3):E569-74. Epub 2008 Jun 24.PMID: 18577690 [PubMed - indexed for MEDLINE]Related articlesFree article