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    Results: 1 to 20 of 137

    1.

    The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma.

    Israel E, Rubin P, Kemp JP, Grossman J, Pierson W, Siegel SC, Tinkelman D, Murray JJ, Busse W, Segal AT, Fish J, Kaiser HB, Ledford D, Wenzel S, Rosenthal R, Cohn J, Lanni C, Pearlman H, Karahalios P, Drazen JM.

    Ann Intern Med. 1993 Dec 1;119(11):1059-66.PMID: 8239223 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Acute and chronic effects of a 5-lipoxygenase inhibitor in asthma: a 6-month randomized multicenter trial. Zileuton Study Group.

    Liu MC, Dubé LM, Lancaster J.

    J Allergy Clin Immunol. 1996 Nov;98(5 Pt 1):859-71.PMID: 8939149 [PubMed - indexed for MEDLINE]Related articles

    3.

    Effect of treatment with zileuton, a 5-lipoxygenase inhibitor, in patients with asthma. A randomized controlled trial. Zileuton Clinical Trial Group.

    Israel E, Cohn J, Dubé L, Drazen JM.

    JAMA. 1996 Mar 27;275(12):931-6.PMID: 8598621 [PubMed - indexed for MEDLINE]Related articles

    4.

    The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin.

    Israel E, Fischer AR, Rosenberg MA, Lilly CM, Callery JC, Shapiro J, Cohn J, Rubin P, Drazen JM.

    Am Rev Respir Dis. 1993 Dec;148(6 Pt 1):1447-51.PMID: 8256883 [PubMed - indexed for MEDLINE]Related articles

    5.

    Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics.

    Dahlén B, Nizankowska E, Szczeklik A, Zetterström O, Bochenek G, Kumlin M, Mastalerz L, Pinis G, Swanson LJ, Boodhoo TI, Wright S, Dubé LM, Dahlén SE.

    Am J Respir Crit Care Med. 1998 Apr;157(4 Pt 1):1187-94.PMID: 9563738 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    A randomized controlled trial comparing zileuton with theophylline in moderate asthma. The Zileuton Study Group.

    Schwartz HJ, Petty T, Dubé LM, Swanson LJ, Lancaster JF.

    Arch Intern Med. 1998 Jan 26;158(2):141-8.PMID: 9448552 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    The effects of a 5-lipoxygenase inhibitor on acute mountain sickness and urinary leukotriene e4 after ascent to high altitude.

    Grissom CK, Richer LD, Elstad MR.

    Chest. 2005 Feb;127(2):565-70.PMID: 15705997 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Treatment of chronic stable asthma with drugs active on the 5-lipoxygenase pathway.

    Drazen JM, Israel E.

    Int Arch Allergy Immunol. 1995 May-Jun;107(1-3):319-20. Review.PMID: 7613158 [PubMed - indexed for MEDLINE]Related articles

    9.

    Zileuton added to low-dose inhaled beclomethasone for the treatment of moderate to severe persistent asthma.

    O'Connor BJ, Löfdahl CG, Balter M, Szczeklik A, Boulet LP, Cairns CB.

    Respir Med. 2007 Jun;101(6):1088-96. Epub 2007 Mar 13.PMID: 17360171 [PubMed - indexed for MEDLINE]Related articles

    10.

    Randomized trial of zileuton in patients with moderate asthma: effect of reduced dosing frequency and amounts on pulmonary function and asthma symptoms. Zileuton Study Group.

    DuBuske LM, Grossman J, Dubé LM, Swanson LJ, Lancaster JF.

    Am J Manag Care. 1997 Apr;3(4):633-40.PMID: 10169531 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Effect of a 5-lipoxygenase inhibitor on leukotriene generation and airway responses after allergen challenge in asthmatic patients.

    Hui KP, Taylor IK, Taylor GW, Rubin P, Kesterson J, Barnes NC, Barnes PJ.

    Thorax. 1991 Mar;46(3):184-9.PMID: 1851340 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Efficacy and tolerability of fluticasone propionate/salmeterol administered twice daily via hydrofluoroalkane 134a metered-dose inhaler in adolescent and adult patients with persistent asthma: a randomized, double-blind, placebo-controlled, 12-week study.

    Nathan RA, Rooklin A, Schoaf L, Scott C, Ellsworth A, House K, Dorinsky P.

    Clin Ther. 2006 Jan;28(1):73-85.PMID: 16490581 [PubMed - indexed for MEDLINE]Related articles

    13.

    Effect of chronic 5-lipoxygenase inhibition on airway hyperresponsiveness in asthmatic subjects.

    Fischer AR, McFadden CA, Frantz R, Awni WM, Cohn J, Drazen JM, Israel E.

    Am J Respir Crit Care Med. 1995 Oct;152(4 Pt 1):1203-7.PMID: 7551371 [PubMed - indexed for MEDLINE]Related articles

    14.

    Efficacy of zileuton controlled-release tablets administered twice daily in the treatment of moderate persistent asthma: a 3-month randomized controlled study.

    Nelson H, Kemp J, Berger W, Corren J, Casale T, Dube L, Walton-Bowen K, LaVallee N, Stepanians M.

    Ann Allergy Asthma Immunol. 2007 Aug;99(2):178-84.PMID: 17718106 [PubMed - indexed for MEDLINE]Related articles

    15.

    A pilot study of zileuton, a novel selective 5-lipoxygenase inhibitor, in patients with systemic lupus erythematosus.

    Hackshaw KV, Shi Y, Brandwein SR, Jones K, Westcott JY.

    J Rheumatol. 1995 Mar;22(3):462-8.PMID: 7783062 [PubMed - indexed for MEDLINE]Related articles

    16.

    Inhibition of exercise-induced bronchospasm by zileuton: a 5-lipoxygenase inhibitor.

    Meltzer SS, Hasday JD, Cohn J, Bleecker ER.

    Am J Respir Crit Care Med. 1996 Mar;153(3):931-5.PMID: 8630575 [PubMed - indexed for MEDLINE]Related articles

    17.

    Effects of a 5-lipoxygenase inhibitor, ABT-761, on exercise-induced bronchoconstriction and urinary LTE4 in asthmatic patients.

    Lehnigk B, Rabe KF, Dent G, Herst RS, Carpentier PJ, Magnussen H.

    Eur Respir J. 1998 Mar;11(3):617-23.PMID: 9596112 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Combined salmeterol/fluticasone propionate versus fluticasone propionate alone in mild asthma : a placebo-controlled comparison.

    Boonsawat W, Goryachkina L, Jacques L, Frith L.

    Clin Drug Investig. 2008;28(2):101-11.PMID: 18211118 [PubMed - indexed for MEDLINE]Related articles

    19.

    Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthma.

    Fischer AR, Rosenberg MA, Lilly CM, Callery JC, Rubin P, Cohn J, White MV, Igarashi Y, Kaliner MA, Drazen JM, et al.

    J Allergy Clin Immunol. 1994 Dec;94(6 Pt 1):1046-56.PMID: 7798537 [PubMed - indexed for MEDLINE]Related articles

    20.

    The effects of 5-lipoxygenase inhibition by zileuton on platelet-activating-factor-induced pulmonary abnormalities in mild asthma.

    Gómez FP, Iglesia R, Roca J, Barberà JA, Chung KF, Rodriguez-Roisin R.

    Am J Respir Crit Care Med. 1998 May;157(5 Pt 1):1559-64.PMID: 9603138 [PubMed - indexed for MEDLINE]Related articlesFree article

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