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Misoprostol reduces serious gastrointestinal complications in patients with rheumatoid arthritis receiving nonsteroidal anti-inflammatory drugs. A randomized, double-blind, placebo-controlled trial.

Silverstein FE, Graham DY, Senior JR, Davies HW, Struthers BJ, Bittman RM, Geis GS.

Ann Intern Med. 1995 Aug 15;123(4):241-9.PMID: 7611589 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevention of non-steroidal anti-inflammatory drug-induced gastrointestinal mucosal injury: risk factors for serious complications.

Koch M, Dezi A, Tarquini M, Capurso L.

Dig Liver Dis. 2000 Mar;32(2):138-51.PMID: 10975790 [PubMed - indexed for MEDLINE]Related articles

Risk factors for serious nonsteroidal-induced gastrointestinal complications: regression analysis of the MUCOSA trial.

Simon LS, Hatoum HT, Bittman RM, Archambault WT, Polisson RP.

Fam Med. 1996 Mar;28(3):204-10.PMID: 8900554 [PubMed - indexed for MEDLINE]Related articles

Prevention of gastrointestinal complications associated with nonsteroidal antiinflammatory drugs.

Agrawal NM, Aziz K.

J Rheumatol Suppl. 1998 May;51:17-20.PMID: 9596550 [PubMed - indexed for MEDLINE]Related articles

Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study.

Silverstein FE, Faich G, Goldstein JL, Simon LS, Pincus T, Whelton A, Makuch R, Eisen G, Agrawal NM, Stenson WF, Burr AM, Zhao WW, Kent JD, Lefkowith JB, Verburg KM, Geis GS.

JAMA. 2000 Sep 13;284(10):1247-55.PMID: 10979111 [PubMed - indexed for MEDLINE]Related articlesFree article

Systematic reviews of the clinical effectiveness and cost-effectiveness of proton pump inhibitors in acute upper gastrointestinal bleeding.

Leontiadis GI, Sreedharan A, Dorward S, Barton P, Delaney B, Howden CW, Orhewere M, Gisbert J, Sharma VK, Rostom A, Moayyedi P, Forman D.

Health Technol Assess. 2007 Dec;11(51):iii-iv, 1-164. Review.PMID: 18021578 [PubMed - indexed for MEDLINE]Related articlesFree article

Ulcer recurrence in high-risk patients receiving nonsteroidalanti-inflammatory drugs plus low-dose aspirin: results of a post HOC subanalysis.

Goldstein JL, Huang B, Amer F, Christopoulos NG.

Clin Ther. 2004 Oct;26(10):1637-43.PMID: 15598480 [PubMed - indexed for MEDLINE]Related articles

Misoprostol dosage in the prevention of nonsteroidal anti-inflammatory drug-induced gastric and duodenal ulcers: a comparison of three regimens.

Raskin JB, White RH, Jackson JE, Weaver AL, Tindall EA, Lies RB, Stanton DS.

Ann Intern Med. 1995 Sep 1;123(5):344-50.PMID: 7625622 [PubMed - indexed for MEDLINE]Related articlesFree article

Misoprostol in the treatment of NSAID-induced gastroduodenal lesions.

Ahmed WU, Kirmani SR, Qureshi H, Alam SE, Zuberi SJ.

Indian J Gastroenterol. 1991 Oct;10(4):135-6.PMID: 1748495 [PubMed - indexed for MEDLINE]Related articles

Efficacy and tolerability of pantoprazole compared with misoprostol for the prevention of NSAID-related gastrointestinal lesions and symptoms in rheumatic patients.

Stupnicki T, Dietrich K, González-Carro P, Straszak A, Terjung A, Thomas KB, Lühmann R, Fischer R.

Digestion. 2003;68(4):198-208. Epub 2003 Dec 30.PMID: 14707396 [PubMed - indexed for MEDLINE]Related articles

Reduced risk of upper gastrointestinal ulcer complications with celecoxib, a novel COX-2 inhibitor.

Goldstein JL, Silverstein FE, Agrawal NM, Hubbard RC, Kaiser J, Maurath CJ, Verburg KM, Geis GS.

Am J Gastroenterol. 2000 Jul;95(7):1681-90.PMID: 10925968 [PubMed - indexed for MEDLINE]Related articles

Duodenal and gastric ulcer prevention with misoprostol in arthritis patients taking NSAIDs. Misoprostol Study Group.

Graham DY, White RH, Moreland LW, Schubert TT, Katz R, Jaszewski R, Tindall E, Triadafilopoulos G, Stromatt SC, Teoh LS.

Ann Intern Med. 1993 Aug 15;119(4):257-62.PMID: 8328732 [PubMed - indexed for MEDLINE]Related articlesFree article

Diclofenac/misoprostol compared with diclofenac in the treatment of osteoarthritis of the knee or hip: a randomized, placebo controlled trial. Arthrotec Osteoarthritis Study Group.

Bocanegra TS, Weaver AL, Tindall EA, Sikes DH, Ball JA, Wallemark CB, Geis GS, Fort JG.

J Rheumatol. 1998 Aug;25(8):1602-11.PMID: 9712107 [PubMed - indexed for MEDLINE]Related articles

Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis: a randomized controlled trial.

Simon LS, Weaver AL, Graham DY, Kivitz AJ, Lipsky PE, Hubbard RC, Isakson PC, Verburg KM, Yu SS, Zhao WW, Geis GS.

JAMA. 1999 Nov 24;282(20):1921-8.PMID: 10580457 [PubMed - indexed for MEDLINE]Related articlesFree article

Underutilization of preventive strategies in patients receiving NSAIDs.

Sturkenboom MC, Burke TA, Dieleman JP, Tangelder MJ, Lee F, Goldstein JL.

Rheumatology (Oxford). 2003 Nov;42 Suppl 3:iii23-31.PMID: 14585915 [PubMed - indexed for MEDLINE]Related articlesFree article

Double blind, placebo controlled trial on the cytoprotective effect of misoprostol in subjects with rheumatoid arthritis, osteoarthritis and seronegative spondarthropathy on NSAIDs.

Chandrasekaran AN, Sambandam PR, Lal HM, Ramakrishnan S, Porkodi R, Krishnamurthy V, Achutan K.

J Assoc Physicians India. 1991 Dec;39(12):919-21.PMID: 1816217 [PubMed - indexed for MEDLINE]Related articles

A comparison of the cost-effectiveness of five strategies for the prevention of non-steroidal anti-inflammatory drug-induced gastrointestinal toxicity: a systematic review with economic modelling.

Brown TJ, Hooper L, Elliott RA, Payne K, Webb R, Roberts C, Rostom A, Symmons D.

Health Technol Assess. 2006 Oct;10(38):iii-iv, xi-xiii, 1-183. Review.PMID: 17018227 [PubMed - indexed for MEDLINE]Related articlesFree article

Stratifying the risk of NSAID-related upper gastrointestinal clinical events: results of a double-blind outcomes study in patients with rheumatoid arthritis.

Laine L, Bombardier C, Hawkey CJ, Davis B, Shapiro D, Brett C, Reicin A.

Gastroenterology. 2002 Oct;123(4):1006-12.PMID: 12360461 [PubMed - indexed for MEDLINE]Related articles

Efficacy of misoprostol in the prophylaxis of gastroduodenal lesions induced by short-term nonsteroidal antiinflammatory drug therapy in elderly patients. A multicenter double-blind, placebo-controlled trial.

Piette F, Teillet L, Naudin R, Boichut D, Capron MH.

Rev Rhum Engl Ed. 1997 Apr;64(4):259-66.PMID: 9178399 [PubMed - indexed for MEDLINE]Related articles

Misoprostol prevents NSAID-induced gastroduodenal lesions in patients with osteoarthritis and rheumatoid arthritis.

Saggioro A, Alvisi V, Blasi A, Dobrilla G, Fioravanti A, Marcolongo R.

Ital J Gastroenterol. 1991 Mar-Apr;23(3):119-23. Erratum in: Ital J Gastroenterol 1991 Jun;23(5):273. Marcolengo R [corrected to Marcolongo R]. PMID: 1742504 [PubMed - indexed for MEDLINE]Related articles