Warning: The NCBI web site requires JavaScript to function. more...
Localization of an hTERT repressor region on human chromosome 3p21.3 using chromosome engineering.
Abe S, Tanaka H, Notsu T, Horike S, Fujisaki C, Qi DL, Ohhira T, Gilley D, Oshimura M, Kugoh H.
Genome Integr. 2010 May 26;1(1):6.
Related citations
Downstream E-box-mediated regulation of the human telomerase reverse transcriptase (hTERT) gene transcription: evidence for an endogenous mechanism of transcriptional repression.
Horikawa I, Cable PL, Mazur SJ, Appella E, Afshari CA, Barrett JC.
Mol Biol Cell. 2002 Aug;13(8):2585-97.
Human chromosome 5 carries a transcriptional regulator of human telomerase reverse transcriptase (hTERT).
Qi DL, Ohhira T, Oshimura M, Kugoh H.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):695-701. Epub 2010 Jul 16.
Regulation of human telomerase activity: repression by normal chromosome 3 abolishes nuclear telomerase reverse transcriptase transcripts but does not affect c-Myc activity.
Ducrest AL, Amacker M, Mathieu YD, Cuthbert AP, Trott DA, Newbold RF, Nabholz M, Lingner J.
Cancer Res. 2001 Oct 15;61(20):7594-602.
Human telomerase reverse transcriptase promoter regulation in normal and malignant human ovarian epithelial cells.
Braunstein I, Cohen-Barak O, Shachaf C, Ravel Y, Yalon-Hacohen M, Mills GB, Tzukerman M, Skorecki KL.
Cancer Res. 2001 Jul 15;61(14):5529-36.
Telomerase suppression by chromosome 6 in a human papillomavirus type 16-immortalized keratinocyte cell line and in a cervical cancer cell line.
Steenbergen RD, Kramer D, Meijer CJ, Walboomers JM, Trott DA, Cuthbert AP, Newbold RF, Overkamp WJ, Zdzienicka MZ, Snijders PJ.
J Natl Cancer Inst. 2001 Jun 6;93(11):865-72.
Functional evidence for a telomerase repressor gene on human chromosome 10p15.1.
Nishimoto A, Miura N, Horikawa I, Kugoh H, Murakami Y, Hirohashi S, Kawasaki H, Gazdar AF, Shay JW, Barrett JC, Oshimura M.
Oncogene. 2001 Feb 15;20(7):828-35.
E2F-1 represses transcription of the human telomerase reverse transcriptase gene.
Crowe DL, Nguyen DC, Tsang KJ, Kyo S.
Nucleic Acids Res. 2001 Jul 1;29(13):2789-94.
Opposing regulatory roles of E2F in human telomerase reverse transcriptase (hTERT) gene expression in human tumor and normal somatic cells.
Won J, Yim J, Kim TK.
FASEB J. 2002 Dec;16(14):1943-5. Epub 2002 Oct 4.
Transcriptional regulation of the telomerase hTERT gene as a target for cellular and viral oncogenic mechanisms.
Horikawa I, Barrett JC.
Carcinogenesis. 2003 Jul;24(7):1167-76. Epub 2003 May 22. Review.
Identification of Mad as a repressor of the human telomerase (hTERT) gene.
Oh S, Song YH, Yim J, Kim TK.
Oncogene. 2000 Mar 9;19(11):1485-90.
hTERT transcription is repressed by Cbfa1 in human mesenchymal stem cell populations.
Isenmann S, Cakouros D, Zannettino A, Shi S, Gronthos S.
J Bone Miner Res. 2007 Jun;22(6):897-906.
The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter.
Cong YS, Wen J, Bacchetti S.
Hum Mol Genet. 1999 Jan;8(1):137-42.
Evidence for inactivation of distinct telomerase repressor genes in different types of human cancers.
Tanaka H, Horikawa I, Barrett JC, Oshimura M.
Int J Cancer. 2005 Jul 1;115(4):653-7.
Human chromosome 5 carries a putative telomerase repressor gene.
Kugoh H, Shigenami K, Funaki K, Barrett JC, Oshimura M.
Genes Chromosomes Cancer. 2003 Jan;36(1):37-47.
PAX5 activates the transcription of the human telomerase reverse transcriptase gene in B cells.
Bougel S, Renaud S, Braunschweig R, Loukinov D, Morse HC 3rd, Bosman FT, Lobanenkov V, Benhattar J.
J Pathol. 2010 Jan;220(1):87-96.
Induction of endogenous telomerase (hTERT) by c-Myc in WI-38 fibroblasts transformed with specific genetic elements.
Casillas MA, Brotherton SL, Andrews LG, Ruppert JM, Tollefsbol TO.
Gene. 2003 Oct 16;316:57-65.
A chromosome 3-encoded repressor of the human telomerase reverse transcriptase (hTERT) gene controls the state of hTERT chromatin.
Szutorisz H, Lingner J, Cuthbert AP, Trott DA, Newbold RF, Nabholz M.
Cancer Res. 2003 Feb 1;63(3):689-95.
Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells.
Cong YS, Bacchetti S.
J Biol Chem. 2000 Nov 17;275(46):35665-8.
Identification and characterization of negative regulatory elements of the human telomerase catalytic subunit (hTERT) gene promoter: possible role of MZF-2 in transcriptional repression of hTERT.
Fujimoto K, Kyo S, Takakura M, Kanaya T, Kitagawa Y, Itoh H, Takahashi M, Inoue M.
Nucleic Acids Res. 2000 Jul 1;28(13):2557-62.
Filter your results:
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on