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    Results: 1 to 20 of 102

    1.

    Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus.

    Kariuki SN, Franek BS, Kumar AA, Arrington J, Mikolaitis RA, Utset TO, Jolly M, Crow MK, Skol AD, Niewold TB.

    Arthritis Res Ther. 2010;12(4):R151. Epub 2010 Jul 26.

    PMID:
    20659327
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    2.

    Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

    Chung SA, Taylor KE, Graham RR, Nititham J, Lee AT, Ortmann WA, Jacob CO, Alarcón-Riquelme ME, Tsao BP, Harley JB, Gaffney PM, Moser KL; SLEGEN, Petri M, Demirci FY, Kamboh MI, Manzi S, Gregersen PK, Langefeld CD, Behrens TW, Criswell LA.

    PLoS Genet. 2011 Mar;7(3):e1001323. Epub 2011 Mar 3.

    PMID:
    21408207
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    3.

    Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-α and serologic autoimmunity in lupus patients.

    Robinson T, Kariuki SN, Franek BS, Kumabe M, Kumar AA, Badaracco M, Mikolaitis RA, Guerrero G, Utset TO, Drevlow BE, Zaacks LS, Grober JS, Cohen LM, Kirou KA, Crow MK, Jolly M, Niewold TB.

    J Immunol. 2011 Aug 1;187(3):1298-303. Epub 2011 Jun 24.

    PMID:
    21705624
    [PubMed - indexed for MEDLINE]

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    4.

    Genetics of clinical expression in SLE.

    Namjou B, Kilpatrick J, Harley JB.

    Autoimmunity. 2007 Dec;40(8):602-12. Review.

    PMID:
    18075794
    [PubMed - indexed for MEDLINE]

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    5.

    Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus.

    Taylor KE, Remmers EF, Lee AT, Ortmann WA, Plenge RM, Tian C, Chung SA, Nititham J, Hom G, Kao AH, Demirci FY, Kamboh MI, Petri M, Manzi S, Kastner DL, Seldin MF, Gregersen PK, Behrens TW, Criswell LA.

    PLoS Genet. 2008 May 30;4(5):e1000084.

    PMID:
    18516230
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    6.

    High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus.

    Niewold TB, Hua J, Lehman TJ, Harley JB, Crow MK.

    Genes Immun. 2007 Sep;8(6):492-502. Epub 2007 Jun 21.

    PMID:
    17581626
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    7.

    The PTPN22 C1858T polymorphism is associated with skewing of cytokine profiles toward high interferon-alpha activity and low tumor necrosis factor alpha levels in patients with lupus.

    Kariuki SN, Crow MK, Niewold TB.

    Arthritis Rheum. 2008 Sep;58(9):2818-23.

    PMID:
    18759295
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    8.

    Promoter variant of PIK3C3 is associated with autoimmunity against Ro and Sm epitopes in African-American lupus patients.

    Kariuki SN, Franek BS, Mikolaitis RA, Utset TO, Jolly M, Skol AD, Niewold TB.

    J Biomed Biotechnol. 2010;2010:826434. Epub 2010 Jul 4.

    PMID:
    20671926
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    9.

    Interferon regulatory factors in human lupus pathogenesis.

    Salloum R, Niewold TB.

    Transl Res. 2011 Jun;157(6):326-31. Epub 2011 Feb 8. Review.

    PMID:
    21575916
    [PubMed - indexed for MEDLINE]

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    10.

    Genetic contributions to the autoantibody profile in a rabbit model of Systemic Lupus Erythematosus (SLE).

    Puliyath N, Ray S, Milton J, Mage RG.

    Vet Immunol Immunopathol. 2008 Oct 15;125(3-4):251-67. Epub 2008 Jul 3.

    PMID:
    18602165
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    11.

    Cytokine gene polymorphisms in Colombian patients with systemic lupus erythematosus.

    Guarnizo-Zuccardi P, Lopez Y, Giraldo M, Garcia N, Rodriguez L, Ramirez L, Uribe O, Garcia L, Vasquez G.

    Tissue Antigens. 2007 Nov;70(5):376-82. Epub 2007 Aug 17.

    PMID:
    17711410
    [PubMed - indexed for MEDLINE]

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    12.

    Differential effect of IL10 and TNF{alpha} genotypes on determining susceptibility to discoid and systemic lupus erythematosus.

    Suárez A, López P, Mozo L, Gutiérrez C.

    Ann Rheum Dis. 2005 Nov;64(11):1605-10. Epub 2005 Mar 30.

    PMID:
    15800006
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    13.

    Aberrant genetic control of invariant TCR-bearing NKT cell function in New Zealand mouse strains: possible involvement in systemic lupus erythematosus pathogenesis.

    Tsukamoto K, Ohtsuji M, Shiroiwa W, Lin Q, Nakamura K, Tsurui H, Jiang Y, Sudo K, Nishimura H, Shirai T, Hirose S.

    J Immunol. 2008 Apr 1;180(7):4530-9.

    PMID:
    18354175
    [PubMed - indexed for MEDLINE]
    Free Article

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    14.

    A targeted association study in systemic lupus erythematosus identifies multiple susceptibility alleles.

    Budarf ML, Goyette P, Boucher G, Lian J, Graham RR, Claudio JO, Hudson T, Gladman D, Clarke AE, Pope JE, Peschken C, Smith CD, Hanly J, Rich E, Boire G, Barr SG, Zummer M; GenES Investigators, Fortin PR, Wither J, Rioux JD.

    Genes Immun. 2011 Jan;12(1):51-8. Epub 2010 Oct 21.

    PMID:
    20962850
    [PubMed - indexed for MEDLINE]

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    15.

    Quantitative polymerase chain reaction analysis reveals marked overexpression of interleukin-1 beta, interleukin-1 and interferon-gamma mRNA in the lymph nodes of lupus-prone mice.

    Prud'homme GJ, Kono DH, Theofilopoulos AN.

    Mol Immunol. 1995 May;32(7):495-503.

    PMID:
    7783752
    [PubMed - indexed for MEDLINE]

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    16.

    Age- and gender-specific modulation of serum osteopontin and interferon-alpha by osteopontin genotype in systemic lupus erythematosus.

    Kariuki SN, Moore JG, Kirou KA, Crow MK, Utset TO, Niewold TB.

    Genes Immun. 2009 Jul;10(5):487-94. Epub 2009 Apr 2.

    PMID:
    19339987
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    17.

    Elevated gene expression of Th1/Th2 associated transcription factors is correlated with disease activity in patients with systemic lupus erythematosus.

    Lit LC, Wong CK, Li EK, Tam LS, Lam CW, Lo YM.

    J Rheumatol. 2007 Jan;34(1):89-96. Epub 2006 Nov 15.

    PMID:
    17117487
    [PubMed - indexed for MEDLINE]

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    18.

    Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients.

    Salloum R, Franek BS, Kariuki SN, Rhee L, Mikolaitis RA, Jolly M, Utset TO, Niewold TB.

    Arthritis Rheum. 2010 Feb;62(2):553-61.

    PMID:
    20112359
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    19.

    Genetic regulation of serum cytokines in systemic lupus erythematosus.

    Kariuki SN, Niewold TB.

    Transl Res. 2010 Mar;155(3):109-17. Epub 2009 Sep 25. Review.

    PMID:
    20171594
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    20.

    Fas promoter -670 polymorphism is associated with development of anti-RNP antibodies in systemic lupus erythematosus.

    Lee YH, Kim YR, Ji JD, Sohn J, Song GG.

    J Rheumatol. 2001 Sep;28(9):2008-11.

    PMID:
    11550967
    [PubMed - indexed for MEDLINE]

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