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    Results: 1 to 20 of 95

    1.

    The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?

    Broersen K, Rousseau F, Schymkowitz J.

    Alzheimers Res Ther. 2010 Jul 14;2(4):12.

    PMID:
    20642866
    [PubMed]
    Free PMC Article
    2.

    Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity.

    Varadarajan S, Yatin S, Aksenova M, Butterfield DA.

    J Struct Biol. 2000 Jun;130(2-3):184-208. Review.

    PMID:
    10940225
    [PubMed - indexed for MEDLINE]
    3.

    Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers.

    Laurén J, Gimbel DA, Nygaard HB, Gilbert JW, Strittmatter SM.

    Nature. 2009 Feb 26;457(7233):1128-32.

    PMID:
    19242475
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Assessing the stability of Alzheimer's amyloid protofibrils using molecular dynamics.

    Lemkul JA, Bevan DR.

    J Phys Chem B. 2010 Feb 4;114(4):1652-60.

    PMID:
    20055378
    [PubMed - indexed for MEDLINE]
    5.

    Amyloid-induced neurofibrillary tangle formation in Alzheimer's disease: insight from transgenic mouse and tissue-culture models.

    Götz J, Schild A, Hoerndli F, Pennanen L.

    Int J Dev Neurosci. 2004 Nov;22(7):453-65. Review.

    PMID:
    15465275
    [PubMed - indexed for MEDLINE]
    6.

    [Involvement of beta-amyloid in the etiology of Alzheimer's disease].

    Tomiyama T.

    Brain Nerve. 2010 Jul;62(7):691-9. Review. Japanese.

    PMID:
    20675873
    [PubMed - indexed for MEDLINE]
    7.

    Oligomeric Intermediates in Amyloid Formation: Structure Determination and Mechanisms of Toxicity.

    Fändrich M.

    J Mol Biol. 2012 Jan 12. [Epub ahead of print]

    PMID:
    22248587
    [PubMed - as supplied by publisher]
    8.

    Vaccination as a therapeutic approach to Alzheimer's disease.

    Wisniewski T, Boutajangout A.

    Mt Sinai J Med. 2010 Jan-Feb;77(1):17-31. Review.

    PMID:
    20101719
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    9.

    Stabilization of neurotoxic Alzheimer amyloid-beta oligomers by protein engineering.

    Sandberg A, Luheshi LM, Söllvander S, Pereira de Barros T, Macao B, Knowles TP, Biverstål H, Lendel C, Ekholm-Petterson F, Dubnovitsky A, Lannfelt L, Dobson CM, Härd T.

    Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15595-600. Epub 2010 Aug 16.

    PMID:
    20713699
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    10.

    Amyloid-beta oligomers: possible roles as key neurotoxins in Alzheimer's Disease.

    Lublin AL, Gandy S.

    Mt Sinai J Med. 2010 Jan-Feb;77(1):43-9. Review.

    PMID:
    20101723
    [PubMed - indexed for MEDLINE]
    11.

    Amyloid beta-peptide aggregation. What does it result in and how can it be prevented?

    Nerelius C, Johansson J, Sandegren A.

    Front Biosci. 2009 Jan 1;14:1716-29.

    PMID:
    19273157
    [PubMed - indexed for MEDLINE]
    12.

    Alzheimer's disease and the 'ABSENT' hypothesis: mechanism for amyloid beta endothelial and neuronal toxicity.

    Roy S, Rauk A.

    Med Hypotheses. 2005;65(1):123-37.

    PMID:
    15893129
    [PubMed - indexed for MEDLINE]
    13.

    New developments in mild cognitive impairment and Alzheimer's disease.

    Schott JM, Kennedy J, Fox NC.

    Curr Opin Neurol. 2006 Dec;19(6):552-8. Review.

    PMID:
    17102693
    [PubMed - indexed for MEDLINE]
    14.

    Immunological approaches for amyloid-beta clearance toward treatment for Alzheimer's disease.

    Solomon B.

    Rejuvenation Res. 2008 Apr;11(2):349-57. Review.

    PMID:
    18341423
    [PubMed - indexed for MEDLINE]
    15.

    Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: involvement of endoplasmic reticulum calcium release in oligomer-induced cell death.

    Resende R, Ferreiro E, Pereira C, Resende de Oliveira C.

    Neuroscience. 2008 Aug 26;155(3):725-37. Epub 2008 Jun 19.

    PMID:
    18621106
    [PubMed - indexed for MEDLINE]
    16.

    Vaccination for the prevention and treatment of Alzheimer's disease.

    Solomon B, Frenkel D.

    Drugs Today (Barc). 2000 Sep;36(9):655-63.

    PMID:
    12847570
    [PubMed]
    17.

    Mitochondria in aging and Alzheimer's disease.

    Crouch PJ, Cimdins K, Duce JA, Bush AI, Trounce IA.

    Rejuvenation Res. 2007 Sep;10(3):349-57. Review.

    PMID:
    17708691
    [PubMed - indexed for MEDLINE]
    18.

    Concentration dependent Cu2+ induced aggregation and dityrosine formation of the Alzheimer's disease amyloid-beta peptide.

    Smith DP, Ciccotosto GD, Tew DJ, Fodero-Tavoletti MT, Johanssen T, Masters CL, Barnham KJ, Cappai R.

    Biochemistry. 2007 Mar 13;46(10):2881-91. Epub 2007 Feb 13.

    PMID:
    17297919
    [PubMed - indexed for MEDLINE]
    19.

    Inhibiting the conversion of soluble amyloid-beta peptide into abnormally folded amyloidogenic intermediates: relevance for Alzheimer's disease therapy.

    Soto C, Saborio GP, Permanne B.

    Acta Neurol Scand Suppl. 2000;176:90-5.

    PMID:
    11261811
    [PubMed - indexed for MEDLINE]
    20.

    Solution conformations and aggregational properties of synthetic amyloid beta-peptides of Alzheimer's disease. Analysis of circular dichroism spectra.

    Barrow CJ, Yasuda A, Kenny PT, Zagorski MG.

    J Mol Biol. 1992 Jun 20;225(4):1075-93.

    PMID:
    1613791
    [PubMed - indexed for MEDLINE]

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