PubMed

COU254, a specific 3-carboxamide-coumarin inhibitor of coagulation factor XII, does not protect mice from acute ischemic stroke.

Kraft P, Schwarz T, Pochet L, Stoll G, Kleinschnitz C.

Exp Transl Stroke Med. 2010 Feb 15;2(1):5.PMID: 20298537 [PubMed]Free PMC ArticleFree textRelated citations

Thrombin-activatable fibrinolysis inhibitor (TAFI) deficient mice are susceptible to intracerebral thrombosis and ischemic stroke.

Kraft P, Schwarz T, Meijers JC, Stoll G, Kleinschnitz C.

PLoS One. 2010 Jul 19;5(7):e11658.PMID: 20657835 [PubMed - in process]Free PMC ArticleFree textRelated citations

Enhanced cortical reperfusion protects coagulation factor XII-deficient mice from ischemic stroke as revealed by high-field MRI.

Pham M, Kleinschnitz C, Helluy X, Bartsch AJ, Austinat M, Behr VC, Renné T, Nieswandt B, Stoll G, Bendszus M.

Neuroimage. 2010 Feb 15;49(4):2907-14. Epub 2009 Dec 1.PMID: 19958838 [PubMed - indexed for MEDLINE]Related citations

Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis.

Kleinschnitz C, Stoll G, Bendszus M, Schuh K, Pauer HU, Burfeind P, Renné C, Gailani D, Nieswandt B, Renné T.

J Exp Med. 2006 Mar 20;203(3):513-8. Epub 2006 Mar 13.PMID: 16533887 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Targeting platelets in acute experimental stroke: impact of glycoprotein Ib, VI, and IIb/IIIa blockade on infarct size, functional outcome, and intracranial bleeding.

Kleinschnitz C, Pozgajova M, Pham M, Bendszus M, Nieswandt B, Stoll G.

Circulation. 2007 May 1;115(17):2323-30. Epub 2007 Apr 16.PMID: 17438148 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Trial design and reporting standards for intra-arterial cerebral thrombolysis for acute ischemic stroke.

Higashida RT, Furlan AJ, Roberts H, Tomsick T, Connors B, Barr J, Dillon W, Warach S, Broderick J, Tilley B, Sacks D; Technology Assessment Committee of the American Society of Interventional and Therapeutic Neuroradiology; Technology Assessment Committee of the Society of Interventional Radiology.

Stroke. 2003 Aug;34(8):e109-37. Epub 2003 Jul 17. Erratum in: Stroke. 2003 Nov;34(11):2774. PMID: 12869717 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Inhibition of factor Xa reduces ischemic brain damage after thromboembolic stroke in rats.

Wang X, Xu L, Wang H, Grzanna R, Zhan Y, Knabb RM, Luettgen JM, Bozarth TA, Galemmo RA, Wong PC, Bernard R, Vargas H, Chopp M, Friedman SM, Feuerstein GZ.

Stroke. 2003 Feb;34(2):468-74.PMID: 12574562 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

The intrinsic pathway of coagulation is essential for thrombus stability in mice.

Renné T, Nieswandt B, Gailani D.

Blood Cells Mol Dis. 2006 Mar-Apr;36(2):148-51. Epub 2006 Feb 8.PMID: 16466946 [PubMed - indexed for MEDLINE]Related citations

Defective thrombus formation in mice lacking coagulation factor XII.

Renné T, Pozgajová M, Grüner S, Schuh K, Pauer HU, Burfeind P, Gailani D, Nieswandt B.

J Exp Med. 2005 Jul 18;202(2):271-81. Epub 2005 Jul 11.PMID: 16009717 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Allopregnanolone, a progesterone metabolite, is more effective than progesterone in reducing cortical infarct volume after transient middle cerebral artery occlusion.

Sayeed I, Guo Q, Hoffman SW, Stein DG.

Ann Emerg Med. 2006 Apr;47(4):381-9. Epub 2006 Feb 21.PMID: 16546625 [PubMed - indexed for MEDLINE]Related citations

Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment.

Stoll G, Kleinschnitz C, Nieswandt B.

Blood. 2008 Nov 1;112(9):3555-62. Epub 2008 Aug 1. Review.PMID: 18676880 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Reduced microvascular thrombosis and improved outcome in acute murine stroke by inhibiting GP IIb/IIIa receptor-mediated platelet aggregation.

Choudhri TF, Hoh BL, Zerwes HG, Prestigiacomo CJ, Kim SC, Connolly ES Jr, Kottirsch G, Pinsky DJ.

J Clin Invest. 1998 Oct 1;102(7):1301-10.PMID: 9769322 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

CD18-mediated neutrophil recruitment contributes to the pathogenesis of reperfused but not nonreperfused stroke.

Prestigiacomo CJ, Kim SC, Connolly ES Jr, Liao H, Yan SF, Pinsky DJ.

Stroke. 1999 May;30(5):1110-7.PMID: 10229752 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Effects of the cyclooxygenase-2 inhibitor nimesulide on cerebral infarction and neurological deficits induced by permanent middle cerebral artery occlusion in the rat.

Candelario-Jalil E, Mhadu NH, González-Falcón A, García-Cabrera M, Muñoz E, León OS, Fiebich BL.

J Neuroinflammation. 2005 Jan 18;2(1):3.PMID: 15656909 [PubMed - as supplied by publisher]Free PMC ArticleFree textRelated citations

Factor XIIa inhibitor recombinant human albumin Infestin-4 abolishes occlusive arterial thrombus formation without affecting bleeding.

Hagedorn I, Schmidbauer S, Pleines I, Kleinschnitz C, Kronthaler U, Stoll G, Dickneite G, Nieswandt B.

Circulation. 2010 Apr 6;121(13):1510-7. Epub 2010 Mar 22.PMID: 20308613 [PubMed - indexed for MEDLINE]Related citations

SB 234551 selective ET(A) receptor antagonism: perfusion/diffusion MRI used to define treatable stroke model, time to treatment and mechanism of protection.

Legos JJ, Lenhard SC, Haimbach RE, Schaeffer TR, Bentley RG, McVey MJ, Chandra S, Irving EA, Andrew A Parsons, Barone FC.

Exp Neurol. 2008 Jul;212(1):53-62. Epub 2008 Mar 25.PMID: 18462720 [PubMed - indexed for MEDLINE]Related citations

Postischemic cerebrovascular E-selectin expression mediates tissue injury in murine stroke.

Huang J, Choudhri TF, Winfree CJ, McTaggart RA, Kiss S, Mocco J, Kim LJ, Protopsaltis TS, Zhang Y, Pinsky DJ, Connolly ES Jr.

Stroke. 2000 Dec;31(12):3047-53.PMID: 11108771 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Cerebral protection in homozygous null ICAM-1 mice after middle cerebral artery occlusion. Role of neutrophil adhesion in the pathogenesis of stroke.

Connolly ES Jr, Winfree CJ, Springer TA, Naka Y, Liao H, Yan SD, Stern DM, Solomon RA, Gutierrez-Ramos JC, Pinsky DJ.

J Clin Invest. 1996 Jan 1;97(1):209-16.PMID: 8550836 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Long-term changes of functional MRI-based brain function, behavioral status, and histopathology after transient focal cerebral ischemia in rats.

Sicard KM, Henninger N, Fisher M, Duong TQ, Ferris CF.

Stroke. 2006 Oct;37(10):2593-600. Epub 2006 Aug 31.PMID: 16946164 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Pharmacological regulation of factor XII activation may be a new target to control pathological coagulation.

Schousboe I.

Biochem Pharmacol. 2008 Mar 1;75(5):1007-13. Epub 2007 Oct 7. Review.PMID: 17996217 [PubMed - indexed for MEDLINE]Related citations