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    Results: 1 to 20 of 88

    1.

    Methylnaltrexone potentiates the anti-angiogenic effects of mTOR inhibitors.

    Singleton PA, Mambetsariev N, Lennon FE, Mathew B, Siegler JH, Moreno-Vinasco L, Salgia R, Moss J, Garcia JG.

    J Angiogenes Res. 2010 Feb 19;2(1):5.

    PMID:
    20298531
    [PubMed]
    Free PMC Article
    2.
    3.

    Methylnaltrexone inhibits opiate and VEGF-induced angiogenesis: role of receptor transactivation.

    Singleton PA, Lingen MW, Fekete MJ, Garcia JG, Moss J.

    Microvasc Res. 2006 Jul-Sep;72(1-2):3-11. Epub 2006 Jul 3.

    PMID:
    16820176
    [PubMed - indexed for MEDLINE]
    4.

    Antiangiogenic potential of the Mammalian target of rapamycin inhibitor temsirolimus.

    Del Bufalo D, Ciuffreda L, Trisciuoglio D, Desideri M, Cognetti F, Zupi G, Milella M.

    Cancer Res. 2006 Jun 1;66(11):5549-54.

    PMID:
    16740688
    [PubMed - indexed for MEDLINE]
    Free Article
    5.

    Attenuation of vascular permeability by methylnaltrexone: role of mOP-R and S1P3 transactivation.

    Singleton PA, Moreno-Vinasco L, Sammani S, Wanderling SL, Moss J, Garcia JG.

    Am J Respir Cell Mol Biol. 2007 Aug;37(2):222-31. Epub 2007 Mar 29.

    PMID:
    17395891
    [PubMed - indexed for MEDLINE]
    Free Article
    6.

    15(S)-hydroxyeicosatetraenoic acid induces angiogenesis via activation of PI3K-Akt-mTOR-S6K1 signaling.

    Zhang B, Cao H, Rao GN.

    Cancer Res. 2005 Aug 15;65(16):7283-91.

    PMID:
    16103079
    [PubMed - indexed for MEDLINE]
    Free Article
    7.

    AKT activity regulates the ability of mTOR inhibitors to prevent angiogenesis and VEGF expression in multiple myeloma cells.

    Frost P, Shi Y, Hoang B, Lichtenstein A.

    Oncogene. 2007 Apr 5;26(16):2255-62. Epub 2006 Oct 2.

    PMID:
    17016437
    [PubMed - indexed for MEDLINE]
    8.

    Pravastatin induces rat aortic endothelial cell proliferation and migration via activation of PI3K/Akt/mTOR/p70 S6 kinase signaling.

    Nakao T, Shiota M, Tatemoto Y, Izumi Y, Iwao H.

    J Pharmacol Sci. 2007 Dec;105(4):334-41. Epub 2007 Dec 1.

    PMID:
    18057776
    [PubMed - indexed for MEDLINE]
    Free Article
    9.

    Effect of Src kinase inhibition on metastasis and tumor angiogenesis in human pancreatic cancer.

    Ischenko I, Guba M, Yezhelyev M, Papyan A, Schmid G, Green T, Fennell M, Jauch KW, Bruns CJ.

    Angiogenesis. 2007;10(3):167-82. Epub 2007 May 8.

    PMID:
    17486419
    [PubMed - indexed for MEDLINE]
    10.

    mTOR inhibitor RAD001 (everolimus) has antiangiogenic/vascular properties distinct from a VEGFR tyrosine kinase inhibitor.

    Lane HA, Wood JM, McSheehy PM, Allegrini PR, Boulay A, Brueggen J, Littlewood-Evans A, Maira SM, Martiny-Baron G, Schnell CR, Sini P, O'Reilly T.

    Clin Cancer Res. 2009 Mar 1;15(5):1612-22. Epub 2009 Feb 17.

    PMID:
    19223496
    [PubMed - indexed for MEDLINE]
    Free Article
    13.

    CEP-7055: a novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models.

    Ruggeri B, Singh J, Gingrich D, Angeles T, Albom M, Yang S, Chang H, Robinson C, Hunter K, Dobrzanski P, Jones-Bolin S, Pritchard S, Aimone L, Klein-Szanto A, Herbert JM, Bono F, Schaeffer P, Casellas P, Bourie B, Pili R, Isaacs J, Ator M, Hudkins R, Vaught J, Mallamo J, Dionne C.

    Cancer Res. 2003 Sep 15;63(18):5978-91. Erratum in: Cancer Res. 2003 Nov 1;63(21):7543.

    PMID:
    14522925
    [PubMed - indexed for MEDLINE]
    Free Article
    14.

    Anti-angiogenic activity of carebastine: a plausible mechanism affecting airway remodelling.

    De Luisi A, Mangialardi G, Ria R, Acuto G, Ribatti D, Vacca A.

    Eur Respir J. 2009 Oct;34(4):958-66. Epub 2009 Apr 8.

    PMID:
    19357149
    [PubMed - indexed for MEDLINE]
    Free Article
    15.

    PE, a new sulfated saponin from sea cucumber, exhibits anti-angiogenic and anti-tumor activities in vitro and in vivo.

    Tian F, Zhang X, Tong Y, Yi Y, Zhang S, Li L, Sun P, Lin L, Ding J.

    Cancer Biol Ther. 2005 Aug;4(8):874-82.

    PMID:
    16082187
    [PubMed - indexed for MEDLINE]
    Free Article
    16.

    Endothelial monocyte activating polypeptide II interferes with VEGF-induced proangiogenic signaling.

    Awasthi N, Schwarz MA, Verma V, Cappiello C, Schwarz RE.

    Lab Invest. 2009 Jan;89(1):38-46. Epub 2008 Nov 10.

    PMID:
    19002109
    [PubMed - indexed for MEDLINE]
    Free Article
    17.

    A novel Src kinase inhibitor, M475271, inhibits VEGF-induced human umbilical vein endothelial cell proliferation and migration.

    Ali N, Yoshizumi M, Fujita Y, Izawa Y, Kanematsu Y, Ishizawa K, Tsuchiya K, Yano S, Sone S, Tamaki T.

    J Pharmacol Sci. 2005 Jun;98(2):130-41. Epub 2005 Jun 4.

    PMID:
    15937404
    [PubMed - indexed for MEDLINE]
    Free Article
    18.

    Low-scale phosphoproteome analyses identify the mTOR effector p70 S6 kinase 1 as a specific biomarker of the dual-HER1/HER2 tyrosine kinase inhibitor lapatinib (Tykerb) in human breast carcinoma cells.

    Vazquez-Martin A, Oliveras-Ferraros C, Colomer R, Brunet J, Menendez JA.

    Ann Oncol. 2008 Jun;19(6):1097-109. Epub 2008 Feb 17.

    PMID:
    18283037
    [PubMed - indexed for MEDLINE]
    Free Article
    19.

    Targeting heat-shock protein 90 improves efficacy of rapamycin in a model of hepatocellular carcinoma in mice.

    Lang SA, Moser C, Fichnter-Feigl S, Schachtschneider P, Hellerbrand C, Schmitz V, Schlitt HJ, Geissler EK, Stoeltzing O.

    Hepatology. 2009 Feb;49(2):523-32.

    PMID:
    19085954
    [PubMed - indexed for MEDLINE]
    20.

    S9, a novel anticancer agent, exerts its anti-proliferative activity by interfering with both PI3K-Akt-mTOR signaling and microtubule cytoskeleton.

    Zhang C, Yang N, Yang CH, Ding HS, Luo C, Zhang Y, Wu MJ, Zhang XW, Shen X, Jiang HL, Meng LH, Ding J.

    PLoS One. 2009;4(3):e4881. Epub 2009 Mar 18.

    PMID:
    19293927
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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