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AMPK exerts dual regulatory effects on the PI3K pathway.
Tao R, Gong J, Luo X, Zang M, Guo W, Wen R, Luo Z.
J Mol Signal. 2010 Feb 18;5(1):1.PMID: 20167101 [PubMed - in process]Free PMC ArticleFree textRelated citations
Role of adenosine 5'-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target of rapamycin signaling.
Deshmukh AS, Treebak JT, Long YC, Viollet B, Wojtaszewski JF, Zierath JR.
Mol Endocrinol. 2008 May;22(5):1105-12. Epub 2008 Feb 14.PMID: 18276828 [PubMed - indexed for MEDLINE]Free ArticleRelated citations
Effects of stimulation of AMP-activated protein kinase on insulin-like growth factor 1- and epidermal growth factor-dependent extracellular signal-regulated kinase pathway.
Kim J, Yoon MY, Choi SL, Kang I, Kim SS, Kim YS, Choi YK, Ha J.
J Biol Chem. 2001 Jun 1;276(22):19102-10. Epub 2001 Mar 21.PMID: 11262401 [PubMed - indexed for MEDLINE]Free ArticleRelated citations
Regulation of phosphoinositide metabolism, Akt phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes.
Ono H, Katagiri H, Funaki M, Anai M, Inukai K, Fukushima Y, Sakoda H, Ogihara T, Onishi Y, Fujishiro M, Kikuchi M, Oka Y, Asano T.
Mol Endocrinol. 2001 Aug;15(8):1411-22.PMID: 11463863 [PubMed - indexed for MEDLINE]Free ArticleRelated citations
A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway.
Kimura N, Tokunaga C, Dalal S, Richardson C, Yoshino K, Hara K, Kemp BE, Witters LA, Mimura O, Yonezawa K.
Genes Cells. 2003 Jan;8(1):65-79.PMID: 12558800 [PubMed - indexed for MEDLINE]Related citations
AMP-activated protein kinase enhances the expression of muscle-specific ubiquitin ligases despite its activation of IGF-1/Akt signaling in C2C12 myotubes.
Tong JF, Yan X, Zhu MJ, Du M.
J Cell Biochem. 2009 Oct 1;108(2):458-68.PMID: 19639604 [PubMed - indexed for MEDLINE]Related citations
Disruption of AMPKalpha1 signaling prevents AICAR-induced inhibition of AS160/TBC1D4 phosphorylation and glucose uptake in primary rat adipocytes.
Gaidhu MP, Perry RL, Noor F, Ceddia RB.
Mol Endocrinol. 2010 Jul;24(7):1434-40. Epub 2010 May 25.PMID: 20501641 [PubMed - in process]Related citations
Serine-385 phosphorylation of inwardly rectifying K+ channel subunit (Kir6.2) by AMP-dependent protein kinase plays a key role in rosiglitazone-induced closure of the K(ATP) channel and insulin secretion in rats.
Chang TJ, Chen WP, Yang C, Lu PH, Liang YC, Su MJ, Lee SC, Chuang LM.
Diabetologia. 2009 Jun;52(6):1112-21. Epub 2009 Apr 9.PMID: 19357830 [PubMed - indexed for MEDLINE]Related citations
Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy.
Sengupta TK, Leclerc GM, Hsieh-Kinser TT, Leclerc GJ, Singh I, Barredo JC.
Mol Cancer. 2007 Jul 10;6:46.PMID: 17623090 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations
Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells.
Morrow VA, Foufelle F, Connell JM, Petrie JR, Gould GW, Salt IP.
J Biol Chem. 2003 Aug 22;278(34):31629-39. Epub 2003 Jun 4.PMID: 12791703 [PubMed - indexed for MEDLINE]Free ArticleRelated citations
5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes.
Salt IP, Connell JM, Gould GW.
Diabetes. 2000 Oct;49(10):1649-56.PMID: 11016448 [PubMed - indexed for MEDLINE]Free ArticleRelated citations
Activation of AMP-activated protein kinase suppresses oxidized low-density lipoprotein-induced macrophage proliferation.
Ishii N, Matsumura T, Kinoshita H, Motoshima H, Kojima K, Tsutsumi A, Kawasaki S, Yano M, Senokuchi T, Asano T, Nishikawa T, Araki E.
J Biol Chem. 2009 Dec 11;284(50):34561-9. Epub 2009 Oct 20.PMID: 19843515 [PubMed - indexed for MEDLINE]Related citations
Activators of AMP-activated protein kinase enhance GLUT4 translocation and its glucose transport activity in 3T3-L1 adipocytes.
Yamaguchi S, Katahira H, Ozawa S, Nakamichi Y, Tanaka T, Shimoyama T, Takahashi K, Yoshimoto K, Imaizumi MO, Nagamatsu S, Ishida H.
Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E643-9. Epub 2005 May 31.PMID: 15928020 [PubMed - indexed for MEDLINE]Free ArticleRelated citations
Insulin signalling downstream of protein kinase B is potentiated by 5'AMP-activated protein kinase in rat hearts in vivo.
Longnus SL, Ségalen C, Giudicelli J, Sajan MP, Farese RV, Van Obberghen E.
Diabetologia. 2005 Dec;48(12):2591-601. Epub 2005 Nov 11.PMID: 16283248 [PubMed - indexed for MEDLINE]Related citations
Inhibition of GLUT4 translocation by Tbc1d1, a Rab GTPase-activating protein abundant in skeletal muscle, is partially relieved by AMP-activated protein kinase activation.
Chavez JA, Roach WG, Keller SR, Lane WS, Lienhard GE.
J Biol Chem. 2008 Apr 4;283(14):9187-95. Epub 2008 Feb 7.PMID: 18258599 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations
Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.
Ugi S, Imamura T, Maegawa H, Egawa K, Yoshizaki T, Shi K, Obata T, Ebina Y, Kashiwagi A, Olefsky JM.
Mol Cell Biol. 2004 Oct;24(19):8778-89.PMID: 15367694 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations
Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle.
Kramer HF, Witczak CA, Fujii N, Jessen N, Taylor EB, Arnolds DE, Sakamoto K, Hirshman MF, Goodyear LJ.
Diabetes. 2006 Jul;55(7):2067-76.PMID: 16804077 [PubMed - indexed for MEDLINE]Free ArticleRelated citations
5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside reduces glucose uptake via the inhibition of Na+/H+ exchanger 1 in isolated rat ventricular cardiomyocytes.
Ségalen C, Longnus SL, Baetz D, Counillon L, Van Obberghen E.
Endocrinology. 2008 Apr;149(4):1490-8. Epub 2008 Jan 10.PMID: 18187546 [PubMed - indexed for MEDLINE]Free ArticleRelated citations
Agonist-modulated regulation of AMP-activated protein kinase (AMPK) in endothelial cells. Evidence for an AMPK -> Rac1 -> Akt -> endothelial nitric-oxide synthase pathway.
Levine YC, Li GK, Michel T.
J Biol Chem. 2007 Jul 13;282(28):20351-64. Epub 2007 May 22.PMID: 17519230 [PubMed - indexed for MEDLINE]Free ArticleRelated citations
AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver.
Horike N, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Kamata H, Nishiyama K, Uchijima Y, Kurihara Y, Kurihara H, Asano T.
J Biol Chem. 2008 Dec 5;283(49):33902-10. Epub 2008 Sep 17.PMID: 18801732 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations
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