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    Results: 1 to 20 of 100

    2.

    Real-time in vivo imaging of p16Ink4a reveals cross talk with p53.

    Yamakoshi K, Takahashi A, Hirota F, Nakayama R, Ishimaru N, Kubo Y, Mann DJ, Ohmura M, Hirao A, Saya H, Arase S, Hayashi Y, Nakao K, Matsumoto M, Ohtani N, Hara E.

    J Cell Biol. 2009 Aug 10;186(3):393-407.

    PMID:
    19667129
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    Senescence of human fibroblasts induced by oncogenic Raf.

    Zhu J, Woods D, McMahon M, Bishop JM.

    Genes Dev. 1998 Oct 1;12(19):2997-3007.

    PMID:
    9765202
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Hepatitis B virus X protein overcomes stress-induced premature senescence by repressing p16(INK4a) expression via DNA methylation.

    Kim YJ, Jung JK, Lee SY, Jang KL.

    Cancer Lett. 2010 Feb 28;288(2):226-35. Epub 2009 Aug 4.

    PMID:
    19656618
    [PubMed - indexed for MEDLINE]
    5.

    Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts.

    Alcorta DA, Xiong Y, Phelps D, Hannon G, Beach D, Barrett JC.

    Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13742-7.

    PMID:
    8943005
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    Senescence delay of human diploid fibroblast induced by anti-sense p16INK4a expression.

    Duan J, Zhang Z, Tong T.

    J Biol Chem. 2001 Dec 21;276(51):48325-31. Epub 2001 Oct 17.

    PMID:
    11606567
    [PubMed - indexed for MEDLINE]
    Free Article
    7.

    Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner and follow expression of p16(ink4a).

    Kosar M, Bartkova J, Hubackova S, Hodny Z, Lukas J, Bartek J.

    Cell Cycle. 2011 Feb 1;10(3):457-68. Epub 2011 Feb 1.

    PMID:
    21248468
    [PubMed - indexed for MEDLINE]
    8.

    Transcriptional factor HBP1 targets P16(INK4A), upregulating its expression and consequently is involved in Ras-induced premature senescence.

    Li H, Wang W, Liu X, Paulson KE, Yee AS, Zhang X.

    Oncogene. 2010 Sep 9;29(36):5083-94. Epub 2010 Jun 28.

    PMID:
    20581871
    [PubMed - indexed for MEDLINE]
    9.

    Multifaceted regulation of cell cycle progression by estrogen: regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 function.

    Foster JS, Henley DC, Bukovsky A, Seth P, Wimalasena J.

    Mol Cell Biol. 2001 Feb;21(3):794-810.

    PMID:
    11154267
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    10.

    Oncogenic Ras induces p19ARF and growth arrest in mouse embryo fibroblasts lacking p21Cip1 and p27Kip1 without activating cyclin D-dependent kinases.

    Groth A, Weber JD, Willumsen BM, Sherr CJ, Roussel MF.

    J Biol Chem. 2000 Sep 1;275(35):27473-80.

    PMID:
    10842176
    [PubMed - indexed for MEDLINE]
    Free Article
    12.

    p16INK4a-induced senescence is disabled by melanoma-associated mutations.

    Haferkamp S, Becker TM, Scurr LL, Kefford RF, Rizos H.

    Aging Cell. 2008 Oct;7(5):733-45.

    PMID:
    18843795
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    13.

    Id1 regulation of cellular senescence through transcriptional repression of p16/Ink4a.

    Alani RM, Young AZ, Shifflett CB.

    Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):7812-6. Epub 2001 Jun 26.

    PMID:
    11427735
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    Direct evidence from siRNA-directed "knock down" that p16(INK4a) is required for human fibroblast senescence and for limiting ras-induced epithelial cell proliferation.

    Bond J, Jones C, Haughton M, DeMicco C, Kipling D, Wynford-Thomas D.

    Exp Cell Res. 2004 Jan 1;292(1):151-6.

    PMID:
    14720514
    [PubMed - indexed for MEDLINE]
    15.

    BRAFE600-associated senescence-like cell cycle arrest of human naevi.

    Michaloglou C, Vredeveld LC, Soengas MS, Denoyelle C, Kuilman T, van der Horst CM, Majoor DM, Shay JW, Mooi WJ, Peeper DS.

    Nature. 2005 Aug 4;436(7051):720-4.

    PMID:
    16079850
    [PubMed - indexed for MEDLINE]
    Free Article
    16.

    Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes.

    McConnell BB, Gregory FJ, Stott FJ, Hara E, Peters G.

    Mol Cell Biol. 1999 Mar;19(3):1981-9.

    PMID:
    10022885
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    17.

    Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics.

    Dickson MA, Hahn WC, Ino Y, Ronfard V, Wu JY, Weinberg RA, Louis DN, Li FP, Rheinwald JG.

    Mol Cell Biol. 2000 Feb;20(4):1436-47.

    PMID:
    10648628
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.

    P16INK4a is required for hSNF5 chromatin remodeler-induced cellular senescence in malignant rhabdoid tumor cells.

    Oruetxebarria I, Venturini F, Kekarainen T, Houweling A, Zuijderduijn LM, Mohd-Sarip A, Vries RG, Hoeben RC, Verrijzer CP.

    J Biol Chem. 2004 Jan 30;279(5):3807-16. Epub 2003 Nov 6.

    PMID:
    14604992
    [PubMed - indexed for MEDLINE]
    Free Article
    19.

    The relative contributions of the p53 and pRb pathways in oncogene-induced melanocyte senescence.

    Haferkamp S, Tran SL, Becker TM, Scurr LL, Kefford RF, Rizos H.

    Aging (Albany NY). 2009 May 16;1(6):542-56.

    PMID:
    20157537
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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