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    Results: 1 to 20 of 94

    1.

    Application of 3D Zernike descriptors to shape-based ligand similarity searching.

    Venkatraman V, Chakravarthy PR, Kihara D.

    J Cheminform. 2009 Dec 17;1:19.

    PMID:
    20150998
    [PubMed]
    Free PMC Article
    2.

    Comparison of structure- and ligand-based virtual screening protocols considering hit list complementarity and enrichment factors.

    Krüger DM, Evers A.

    ChemMedChem. 2010 Jan;5(1):148-58.

    PMID:
    19908272
    [PubMed - indexed for MEDLINE]
    3.

    Unconventional 2D shape similarity method affords comparable enrichment as a 3D shape method in virtual screening experiments.

    Ebalunode JO, Zheng W.

    J Chem Inf Model. 2009 Jun;49(6):1313-20.

    PMID:
    19480404
    [PubMed - indexed for MEDLINE]
    4.

    Comparison of correlation vector methods for ligand-based similarity searching.

    Fechner U, Franke L, Renner S, Schneider P, Schneider G.

    J Comput Aided Mol Des. 2003 Oct;17(10):687-98.

    PMID:
    15068367
    [PubMed - indexed for MEDLINE]
    5.

    Ultrafast shape recognition: method and applications.

    Ballester PJ.

    Future Med Chem. 2011 Jan;3(1):65-78. Review.

    PMID:
    21428826
    [PubMed - indexed for MEDLINE]
    6.

    The importance of discerning shape in molecular pharmacology.

    Kortagere S, Krasowski MD, Ekins S.

    Trends Pharmacol Sci. 2009 Mar;30(3):138-47. Epub 2009 Jan 31. Review.

    PMID:
    19187977
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    7.

    Shape signatures: a new approach to computer-aided ligand- and receptor-based drug design.

    Zauhar RJ, Moyna G, Tian L, Li Z, Welsh WJ.

    J Med Chem. 2003 Dec 18;46(26):5674-90.

    PMID:
    14667221
    [PubMed - indexed for MEDLINE]
    8.

    Computational methodologies for compound database searching that utilize experimental protein-ligand interaction information.

    Tan L, Batista J, Bajorath J.

    Chem Biol Drug Des. 2010 Sep 1;76(3):191-200. Epub 2010 Jul 15. Review.

    PMID:
    20636330
    [PubMed - indexed for MEDLINE]
    9.

    Novel DOCK clique driven 3D similarity database search tools for molecule shape matching and beyond: adding flexibility to the search for ligand kin.

    Good AC.

    J Mol Graph Model. 2007 Oct;26(3):656-66. Epub 2007 Apr 4.

    PMID:
    17482856
    [PubMed - indexed for MEDLINE]
    10.

    Ultrafast shape recognition: evaluating a new ligand-based virtual screening technology.

    Ballester PJ, Finn PW, Richards WG.

    J Mol Graph Model. 2009 Apr;27(7):836-45. Epub 2009 Jan 14.

    PMID:
    19188082
    [PubMed - indexed for MEDLINE]
    11.

    Similarity-based virtual screening with a bayesian inference network.

    Abdo A, Salim N.

    ChemMedChem. 2009 Feb;4(2):210-8.

    PMID:
    19072820
    [PubMed - indexed for MEDLINE]
    12.

    Scaffold hopping through virtual screening using 2D and 3D similarity descriptors: ranking, voting, and consensus scoring.

    Zhang Q, Muegge I.

    J Med Chem. 2006 Mar 9;49(5):1536-48.

    PMID:
    16509572
    [PubMed - indexed for MEDLINE]
    13.

    LASSO-ligand activity by surface similarity order: a new tool for ligand based virtual screening.

    Reid D, Sadjad BS, Zsoldos Z, Simon A.

    J Comput Aided Mol Des. 2008 Jun-Jul;22(6-7):479-87. Epub 2008 Jan 18.

    PMID:
    18204980
    [PubMed - indexed for MEDLINE]
    14.

    New molecular shape descriptors: application in database screening.

    Good AC, Ewing TJ, Gschwend DA, Kuntz ID.

    J Comput Aided Mol Des. 1995 Feb;9(1):1-12.

    PMID:
    7751866
    [PubMed - indexed for MEDLINE]
    15.

    Chemical database mining through entropy-based molecular similarity assessment of randomly generated structural fragment populations.

    Batista J, Bajorath J.

    J Chem Inf Model. 2007 Jan-Feb;47(1):59-68.

    PMID:
    17238249
    [PubMed - indexed for MEDLINE]
    16.

    Fast protein tertiary structure retrieval based on global surface shape similarity.

    Sael L, Li B, La D, Fang Y, Ramani K, Rustamov R, Kihara D.

    Proteins. 2008 Sep;72(4):1259-73.

    PMID:
    18361455
    [PubMed - indexed for MEDLINE]
    17.

    Support-vector-machine-based ranking significantly improves the effectiveness of similarity searching using 2D fingerprints and multiple reference compounds.

    Geppert H, Horváth T, Gärtner T, Wrobel S, Bajorath J.

    J Chem Inf Model. 2008 Apr;48(4):742-6. Epub 2008 Mar 5.

    PMID:
    18318473
    [PubMed]
    18.

    Toward the discovery of functional transthyretin amyloid inhibitors: application of virtual screening methods.

    Simões CJ, Mukherjee T, Brito RM, Jackson RM.

    J Chem Inf Model. 2010 Oct 25;50(10):1806-20.

    PMID:
    20883031
    [PubMed - indexed for MEDLINE]
    19.

    Similarity metrics for ligands reflecting the similarity of the target proteins.

    Schuffenhauer A, Floersheim P, Acklin P, Jacoby E.

    J Chem Inf Comput Sci. 2003 Mar-Apr;43(2):391-405.

    PMID:
    12653501
    [PubMed - indexed for MEDLINE]
    20.

    An ontology for pharmaceutical ligands and its application for in silico screening and library design.

    Schuffenhauer A, Zimmermann J, Stoop R, van der Vyver JJ, Lecchini S, Jacoby E.

    J Chem Inf Comput Sci. 2002 Jul-Aug;42(4):947-55.

    PMID:
    12132896
    [PubMed - indexed for MEDLINE]

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