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    Results: 1 to 20 of 184

    1.

    Regulation of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase-activating protein/5-lipoxygenase by 4-hydroxynonenal in human osteoarthritic chondrocytes.

    Chen SH, Fahmi H, Shi Q, Benderdour M.

    Arthritis Res Ther. 2010;12(1):R21. Epub 2010 Feb 9.

    PMID:
    20144213
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Regulation of the expression of 5-lipoxygenase-activating protein/5-lipoxygenase and the synthesis of leukotriene B(4) in osteoarthritic chondrocytes: role of transforming growth factor beta and eicosanoids.

    Martel-Pelletier J, Mineau F, Fahmi H, Laufer S, Reboul P, Boileau C, Lavigne M, Pelletier JP.

    Arthritis Rheum. 2004 Dec;50(12):3925-33.

    PMID:
    15593193
    [PubMed - indexed for MEDLINE]
    Free Article
    3.

    The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein.

    Maxis K, Delalandre A, Martel-Pelletier J, Pelletier JP, Duval N, Lajeunesse D.

    Arthritis Res Ther. 2006;8(6):R181.

    PMID:
    17156456
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Differential regulation of cyclooxygenase-2 and inducible nitric oxide synthase by 4-hydroxynonenal in human osteoarthritic chondrocytes through ATF-2/CREB-1 transactivation and concomitant inhibition of NF-kappaB signaling cascade.

    Vaillancourt F, Morquette B, Shi Q, Fahmi H, Lavigne P, Di Battista JA, Fernandes JC, Benderdour M.

    J Cell Biochem. 2007 Apr 1;100(5):1217-31.

    PMID:
    17031850
    [PubMed - indexed for MEDLINE]
    5.

    Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes.

    Li X, Afif H, Cheng S, Martel-Pelletier J, Pelletier JP, Ranger P, Fahmi H.

    J Rheumatol. 2005 May;32(5):887-95.

    PMID:
    15868626
    [PubMed - indexed for MEDLINE]
    6.

    Evaluation of coexpression of microsomal prostaglandin E synthase-1 and cyclooxygenase-2 in interleukin-1-stimulated equine articular chondrocytes.

    Farley J, Sirois J, MacFarlane PH, Kombé A, Laverty S.

    Am J Vet Res. 2005 Nov;66(11):1985-91.

    PMID:
    16334960
    [PubMed - indexed for MEDLINE]
    7.

    Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis.

    Kojima F, Naraba H, Miyamoto S, Beppu M, Aoki H, Kawai S.

    Arthritis Res Ther. 2004;6(4):R355-65. Epub 2004 Jun 8.

    PMID:
    15225371
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    8.

    Hypoxia-inducible factor 1alpha is involved in the prostaglandin metabolism of osteoarthritic cartilage through up-regulation of microsomal prostaglandin E synthase 1 in articular chondrocytes.

    Grimmer C, Pfander D, Swoboda B, Aigner T, Mueller L, Hennig FF, Gelse K.

    Arthritis Rheum. 2007 Dec;56(12):4084-94.

    PMID:
    18050215
    [PubMed - indexed for MEDLINE]
    Free Article
    10.

    Regulation of prostaglandin E(2) synthesis in cells derived from chondrocytes of patients with osteoarthritis.

    Shimpo H, Sakai T, Kondo S, Mishima S, Yoda M, Hiraiwa H, Ishiguro N.

    J Orthop Sci. 2009 Sep;14(5):611-7. Epub 2009 Oct 3.

    PMID:
    19802674
    [PubMed - indexed for MEDLINE]
    11.

    Effects of advanced glycation end products on the expression of COX-2, PGE2 and NO in human osteoarthritic chondrocytes.

    Nah SS, Choi IY, Lee CK, Oh JS, Kim YG, Moon HB, Yoo B.

    Rheumatology (Oxford). 2008 Apr;47(4):425-31. Epub 2008 Feb 19.

    PMID:
    18285354
    [PubMed - indexed for MEDLINE]
    Free Article
    12.

    Up-regulation of microsomal prostaglandin E synthase 1 in osteoarthritic human cartilage: critical roles of the ERK-1/2 and p38 signaling pathways.

    Masuko-Hongo K, Berenbaum F, Humbert L, Salvat C, Goldring MB, Thirion S.

    Arthritis Rheum. 2004 Sep;50(9):2829-38.

    PMID:
    15457451
    [PubMed - indexed for MEDLINE]
    Free Article
    13.

    Signal pathways involved in the regulation of prostaglandin E synthase-1 in human gingival fibroblasts.

    Yucel-Lindberg T, Olsson T, Kawakami T.

    Cell Signal. 2006 Dec;18(12):2131-42.

    PMID:
    16766159
    [PubMed - indexed for MEDLINE]
    14.

    A selective cyclooxygenase-2 inhibitor decreases transforming growth factor-beta1 synthesis and matrix production in human peritoneal mesothelial cells.

    Liu H, Peng Y, Liu F, Li J, Chen X, Liu Y, Zhang H.

    Cell Biol Int. 2007 May;31(5):508-15. Epub 2006 Nov 28.

    PMID:
    17196403
    [PubMed - indexed for MEDLINE]
    15.

    Alterations of metabolic activity in human osteoarthritic osteoblasts by lipid peroxidation end product 4-hydroxynonenal.

    Shi Q, Vaillancourt F, Côté V, Fahmi H, Lavigne P, Afif H, Di Battista JA, Fernandes JC, Benderdour M.

    Arthritis Res Ther. 2006;8(6):R159.

    PMID:
    17042956
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    16.

    Coexpression of microsomal prostaglandin E synthase with cyclooxygenase-2 in human rheumatoid synovial cells.

    Kojima F, Naraba H, Sasaki Y, Okamoto R, Koshino T, Kawai S.

    J Rheumatol. 2002 Sep;29(9):1836-42.

    PMID:
    12233875
    [PubMed - indexed for MEDLINE]
    17.

    Differential regulation of cyclo-oxygenase-2 and 5-lipoxygenase-activating protein (FLAP) expression by glucocorticoids in monocytic cells.

    Goppelt-Struebe M, Schaefer D, Habenicht AJ.

    Br J Pharmacol. 1997 Oct;122(4):619-24.

    PMID:
    9375956
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.
    19.

    Overexpression of COX-2, Prostaglandin E synthase-1 and prostaglandin E receptors in blood mononuclear cells and plaque of patients with carotid atherosclerosis: regulation by nuclear factor-kappaB.

    Gómez-Hernández A, Martín-Ventura JL, Sánchez-Galán E, Vidal C, Ortego M, Blanco-Colio LM, Ortega L, Tuñón J, Egido J.

    Atherosclerosis. 2006 Jul;187(1):139-49. Epub 2005 Oct 4.

    PMID:
    16212965
    [PubMed - indexed for MEDLINE]
    20.

    4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase.

    Vaillancourt F, Fahmi H, Shi Q, Lavigne P, Ranger P, Fernandes JC, Benderdour M.

    Arthritis Res Ther. 2008;10(5):R107. Epub 2008 Sep 9.

    PMID:
    18782442
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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