PubMed

Molecular mechanism of regulation of OGG1: tuberin deficiency results in cytoplasmic redistribution of transcriptional factor NF-YA.

Habib SL.

J Mol Signal. 2009 Dec 29;4:8.PMID: 20040097 [PubMed - in process]Free PMC ArticleFree textRelated citations

Tuberin regulates the DNA repair enzyme OGG1.

Habib SL, Riley DJ, Mahimainathan L, Bhandari B, Choudhury GG, Abboud HE.

Am J Physiol Renal Physiol. 2008 Jan;294(1):F281-90. Epub 2007 Nov 7.PMID: 17989114 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Insight into mechanism of oxidative DNA damage in angiomyolipomas from TSC patients.

Habib SL.

Mol Cancer. 2009 Mar 5;8:13.PMID: 19265534 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Tuberin haploinsufficiency is associated with the loss of OGG1 in rat kidney tumors.

Habib SL, Simone S, Barnes JJ, Abboud HE.

Mol Cancer. 2008 Jan 24;7:10.PMID: 18218111 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Reduced constitutive 8-oxoguanine-DNA glycosylase expression and impaired induction following oxidative DNA damage in the tuberin deficient Eker rat.

Habib SL, Phan MN, Patel SK, Li D, Monks TJ, Lau SS.

Carcinogenesis. 2003 Mar;24(3):573-82.PMID: 12663520 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Mechanism of oxidative DNA damage in diabetes: tuberin inactivation and downregulation of DNA repair enzyme 8-oxo-7,8-dihydro-2'-deoxyguanosine-DNA glycosylase.

Simone S, Gorin Y, Velagapudi C, Abboud HE, Habib SL.

Diabetes. 2008 Oct;57(10):2626-36. Epub 2008 Jul 3.PMID: 18599524 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Novel mechanism of reducing tumourigenesis: Upregulation of the DNA repair enzyme OGG1 by rapamycin-mediated AMPK activation and mTOR inhibition.

Habib SL, Kasinath BS, Rictor R, Veltex S, Velagapudi C.

Eur J Cancer. 2010 Jul 23. [Epub ahead of print]PMID: 20656472 [PubMed - as supplied by publisher]Related citations

Reduction of expression of tuberin, the tuberous-sclerosis-complex-gene-2 product in tuberous sclerosis complex associated connective tissue nevi and sporadic squamous and basal cell carcinomas.

Wienecke R, Klemm E, Karparti S, Swanson NA, Green AJ, DeClue JE.

J Cutan Pathol. 2002 May;29(5):287-90.PMID: 12100629 [PubMed - indexed for MEDLINE]Related citations

Suppression of tumorigenicity by the wild-type tuberous sclerosis 2 (Tsc2) gene and its C-terminal region.

Jin F, Wienecke R, Xiao GH, Maize JC Jr, DeClue JE, Yeung RS.

Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):9154-9.PMID: 8799170 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Localization of tuberous sclerosis 2 mRNA and its protein product tuberin in normal human brain and in cerebral lesions of patients with tuberous sclerosis.

Kerfoot C, Wienecke R, Menchine M, Emelin J, Maize JC Jr, Welsh CT, Norman MG, DeClue JE, Vinters HV.

Brain Pathol. 1996 Oct;6(4):367-75.PMID: 8944308 [PubMed - indexed for MEDLINE]Related citations

Tuberous sclerosis-2 tumor suppressor modulates ERK and B-Raf activity in transformed renal epithelial cells.

Yoon HS, Ramachandiran S, Chacko MA, Monks TJ, Lau SS.

Am J Physiol Renal Physiol. 2004 Feb;286(2):F417-24. Epub 2003 Nov 11.PMID: 14612383 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

The expression of hamartin, the product of the TSC1 gene, in normal human tissues and in TSC1- and TSC2-linked angiomyolipomas.

Plank TL, Logginidou H, Klein-Szanto A, Henske EP.

Mod Pathol. 1999 May;12(5):539-45.PMID: 10349994 [PubMed - indexed for MEDLINE]Related citations

Genetic polymorphisms in OGG1 and their association with angiomyolipoma, a benign kidney tumor in patients with tuberous sclerosis.

Habib SL, Danial E, Nath S, Schneider J, Jenkinson CP, Duggirala R, Abboud HE, Thameem F.

Cancer Biol Ther. 2008 Jan;7(1):23-7. Epub 2007 Oct 8.PMID: 17932460 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Loss of tuberin in both subependymal giant cell astrocytomas and angiomyolipomas supports a two-hit model for the pathogenesis of tuberous sclerosis tumors.

Henske EP, Wessner LL, Golden J, Scheithauer BW, Vortmeyer AO, Zhuang Z, Klein-Szanto AJ, Kwiatkowski DJ, Yeung RS.

Am J Pathol. 1997 Dec;151(6):1639-47.PMID: 9403714 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Platelet-derived growth factor-induced p42/44 mitogen-activated protein kinase activation and cellular growth is mediated by reactive oxygen species in the absence of TSC2/tuberin.

Finlay GA, Thannickal VJ, Fanburg BL, Kwiatkowski DJ.

Cancer Res. 2005 Dec 1;65(23):10881-90.PMID: 16322235 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Renal carcinogenesis, hepatic hemangiomatosis, and embryonic lethality caused by a germ-line Tsc2 mutation in mice.

Kobayashi T, Minowa O, Kuno J, Mitani H, Hino O, Noda T.

Cancer Res. 1999 Mar 15;59(6):1206-11.PMID: 10096549 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Tuberous sclerosis in a 19-week fetus: immunohistochemical and molecular study of hamartin and tuberin.

Wei J, Li P, Chiriboga L, Mizuguchi M, Yee H, Miller DC, Greco MA.

Pediatr Dev Pathol. 2002 Sep-Oct;5(5):448-64. Epub 2002 Sep 4.PMID: 12202993 [PubMed - indexed for MEDLINE]Related citations

Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration.

Astrinidis A, Cash TP, Hunter DS, Walker CL, Chernoff J, Henske EP.

Oncogene. 2002 Dec 5;21(55):8470-6.PMID: 12466966 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Transformation of kidney epithelial cells by a quinol thioether via inactivation of the tuberous sclerosis-2 tumor suppressor gene.

Yoon HS, Monks TJ, Walker CL, Lau SS.

Mol Carcinog. 2001 May;31(1):37-45.PMID: 11398196 [PubMed - indexed for MEDLINE]Related citations

Loss of expression of tuberin and hamartin in tuberous sclerosis complex-associated but not in sporadic angiofibromas.

Fackler I, DeClue JE, Rust H, Vu PA, Kutzner H, Rütten A, Kaddu S, Sander CA, Volkenandt M, Johnson MW, Vinters HV, Wienecke R.

J Cutan Pathol. 2003 Mar;30(3):174-7.PMID: 12641776 [PubMed - indexed for MEDLINE]Related citations