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    Results: 1 to 20 of 96

    1.

    Cancer risk in MLH1, MSH2 and MSH6 mutation carriers; different risk profiles may influence clinical management.

    Ramsoekh D, Wagner A, van Leerdam ME, Dooijes D, Tops CM, Steyerberg EW, Kuipers EJ.

    Hered Cancer Clin Pract. 2009 Dec 23;7(1):17.

    PMID:
    20028567
    [PubMed]
    Free PMC Article
    2.

    Immunohistochemistry and microsatellite instability testing for selecting MLH1, MSH2 and MSH6 mutation carriers in hereditary non-polyposis colorectal cancer.

    Caldés T, Godino J, Sanchez A, Corbacho C, De la Hoya M, Lopez Asenjo J, Saez C, Sanz J, Benito M, Ramon Y Cajal S, Diaz-Rubio E.

    Oncol Rep. 2004 Sep;12(3):621-9.

    PMID:
    15289847
    [PubMed - indexed for MEDLINE]
    3.

    MSH2 mutation carriers are at higher risk of cancer than MLH1 mutation carriers: a study of hereditary nonpolyposis colorectal cancer families.

    Vasen HF, Stormorken A, Menko FH, Nagengast FM, Kleibeuker JH, Griffioen G, Taal BG, Moller P, Wijnen JT.

    J Clin Oncol. 2001 Oct 15;19(20):4074-80.

    PMID:
    11600610
    [PubMed - indexed for MEDLINE]
    4.

    Cumulative incidence of colorectal and extracolonic cancers in MLH1 and MSH2 mutation carriers of hereditary nonpolyposis colorectal cancer.

    Lin KM, Shashidharan M, Thorson AG, Ternent CA, Blatchford GJ, Christensen MA, Watson P, Lemon SJ, Franklin B, Karr B, Lynch J, Lynch HT.

    J Gastrointest Surg. 1998 Jan-Feb;2(1):67-71.

    PMID:
    9841970
    [PubMed - indexed for MEDLINE]
    5.

    Detection of mismatch repair gene germline mutation carrier among Chinese population with colorectal cancer.

    Jin HY, Liu X, Li VK, Ding Y, Yang B, Geng J, Lai R, Ding S, Ni M, Zhao R.

    BMC Cancer. 2008 Feb 7;8:44.

    PMID:
    18257912
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    Phenotype comparison of MLH1 and MSH2 mutation carriers in a cohort of 1,914 individuals undergoing clinical genetic testing in the United States.

    Kastrinos F, Stoffel EM, Balmaña J, Steyerberg EW, Mercado R, Syngal S.

    Cancer Epidemiol Biomarkers Prev. 2008 Aug;17(8):2044-51.

    PMID:
    18708397
    [PubMed - indexed for MEDLINE]
    Free Article
    7.

    Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance.

    Hendriks YM, Wagner A, Morreau H, Menko F, Stormorken A, Quehenberger F, Sandkuijl L, Møller P, Genuardi M, Van Houwelingen H, Tops C, Van Puijenbroek M, Verkuijlen P, Kenter G, Van Mil A, Meijers-Heijboer H, Tan GB, Breuning MH, Fodde R, Wijnen JT, Bröcker-Vriends AH, Vasen H.

    Gastroenterology. 2004 Jul;127(1):17-25.

    PMID:
    15236168
    [PubMed - indexed for MEDLINE]
    8.

    Mutation analysis of the MLH1, MSH2 and MSH6 genes in patients with double primary cancers of the colorectum and the endometrium: a population-based study in northern Sweden.

    Cederquist K, Emanuelsson M, Göransson I, Holinski-Feder E, Müller-Koch Y, Golovleva I, Grönberg H.

    Int J Cancer. 2004 Apr 10;109(3):370-6. Erratum in: Int J Cancer. 2005 Jul 20;115(6):1011.

    PMID:
    14961575
    [PubMed - indexed for MEDLINE]
    9.

    Gene-related cancer spectrum in families with hereditary non-polyposis colorectal cancer (HNPCC).

    Geary J, Sasieni P, Houlston R, Izatt L, Eeles R, Payne SJ, Fisher S, Hodgson SV.

    Fam Cancer. 2008;7(2):163-72. Epub 2007 Oct 16.

    PMID:
    17939062
    [PubMed - indexed for MEDLINE]
    10.

    Lower incidence of colorectal cancer and later age of disease onset in 27 families with pathogenic MSH6 germline mutations compared with families with MLH1 or MSH2 mutations: the German Hereditary Nonpolyposis Colorectal Cancer Consortium.

    Plaschke J, Engel C, Krüger S, Holinski-Feder E, Pagenstecher C, Mangold E, Moeslein G, Schulmann K, Gebert J, von Knebel Doeberitz M, Rüschoff J, Loeffler M, Schackert HK.

    J Clin Oncol. 2004 Nov 15;22(22):4486-94. Epub 2004 Oct 13.

    PMID:
    15483016
    [PubMed - indexed for MEDLINE]
    11.

    Prediction of Lynch syndrome in consecutive patients with colorectal cancer.

    Green RC, Parfrey PS, Woods MO, Younghusband HB.

    J Natl Cancer Inst. 2009 Mar 4;101(5):331-40. Epub 2009 Feb 24.

    PMID:
    19244167
    [PubMed - indexed for MEDLINE]
    Free Article
    12.

    Penetrance of colorectal cancer among MLH1/MSH2 carriers participating in the colorectal cancer familial registry in Ontario.

    Choi YH, Cotterchio M, McKeown-Eyssen G, Neerav M, Bapat B, Boyd K, Gallinger S, McLaughlin J, Aronson M, Briollais L.

    Hered Cancer Clin Pract. 2009 Aug 23;7(1):14.

    PMID:
    19698169
    [PubMed]
    Free PMC Article
    13.

    Association of colonic and endometrial carcinomas in Portuguese families with hereditary nonpolyposis colorectal carcinoma significantly increases the probability of detecting a pathogenic mutation in mismatch repair genes, primarily the MSH2 gene.

    Lage PA, Albuquerque C, Sousa RG, Cravo ML, Salazar M, Francisco I, Maia L, Claro I, Suspiro A, Rodrigues P, Raposo H, Fidalgo PA, Nobre-Leitão C.

    Cancer. 2004 Jul 1;101(1):172-7.

    PMID:
    15222003
    [PubMed - indexed for MEDLINE]
    Free Article
    14.

    Screening for germline mutations of MLH1, MSH2, MSH6 and PMS2 genes in Slovenian colorectal cancer patients: implications for a population specific detection strategy of Lynch syndrome.

    Berginc G, Bracko M, Ravnik-Glavac M, Glavac D.

    Fam Cancer. 2009;8(4):421-9. Epub 2009 Jun 13.

    PMID:
    19526325
    [PubMed - indexed for MEDLINE]
    15.

    Prospective determination of prevalence of lynch syndrome in young women with endometrial cancer.

    Lu KH, Schorge JO, Rodabaugh KJ, Daniels MS, Sun CC, Soliman PT, White KG, Luthra R, Gershenson DM, Broaddus RR.

    J Clin Oncol. 2007 Nov 20;25(33):5158-64. Epub 2007 Oct 9.

    PMID:
    17925543
    [PubMed - indexed for MEDLINE]
    16.

    Lynch Syndrome/Hereditary Non-polyposis Colorectal Cancer (HNPCC).

    Stoffel EM.

    Minerva Gastroenterol Dietol. 2010 Mar;56(1):45-53.

    PMID:
    20190724
    [PubMed - indexed for MEDLINE]
    17.

    Atypical HNPCC owing to MSH6 germline mutations: analysis of a large Dutch pedigree.

    Wagner A, Hendriks Y, Meijers-Heijboer EJ, de Leeuw WJ, Morreau H, Hofstra R, Tops C, Bik E, Bröcker-Vriends AH, van Der Meer C, Lindhout D, Vasen HF, Breuning MH, Cornelisse CJ, van Krimpen C, Niermeijer MF, Zwinderman AH, Wijnen J, Fodde R.

    J Med Genet. 2001 May;38(5):318-22.

    PMID:
    11333868
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.

    A new variant database for mismatch repair genes associated with Lynch syndrome.

    Woods MO, Williams P, Careen A, Edwards L, Bartlett S, McLaughlin JR, Younghusband HB.

    Hum Mutat. 2007 Jul;28(7):669-73.

    PMID:
    17347989
    [PubMed - indexed for MEDLINE]
    19.

    Comprehensive molecular analysis of mismatch repair gene defects in suspected Lynch syndrome (hereditary nonpolyposis colorectal cancer) cases.

    Mueller J, Gazzoli I, Bandipalliam P, Garber JE, Syngal S, Kolodner RD.

    Cancer Res. 2009 Sep 1;69(17):7053-61. Epub 2009 Aug 18.

    PMID:
    19690142
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    20.

    Prediction of a mismatch repair gene defect by microsatellite instability and immunohistochemical analysis in endometrial tumours from HNPCC patients.

    de Leeuw WJ, Dierssen J, Vasen HF, Wijnen JT, Kenter GG, Meijers-Heijboer H, Brocker-Vriends A, Stormorken A, Moller P, Menko F, Cornelisse CJ, Morreau H.

    J Pathol. 2000 Nov;192(3):328-35.

    PMID:
    11054716
    [PubMed - indexed for MEDLINE]

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