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    Results: 1 to 20 of 108

    1.

    Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects.

    Tan B, Naik H, Jang IJ, Yu KS, Kirsch LE, Shin CS, Craft JC, Fleckenstein L.

    Malar J. 2009 Dec 18;8:304.

    PMID:
    20021657
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Population pharmacokinetics of artesunate and dihydroartemisinin in pregnant and non-pregnant women with malaria.

    Morris CA, Onyamboko MA, Capparelli E, Koch MA, Atibu J, Lokomba V, Douoguih M, Hemingway-Foday J, Wesche D, Ryder RW, Bose C, Wright L, Tshefu AK, Meshnick S, Fleckenstein L.

    Malar J. 2011 May 8;10:114.

    PMID:
    21548983
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients.

    Simpson JA, Agbenyega T, Barnes KI, Di Perri G, Folb P, Gomes M, Krishna S, Krudsood S, Looareesuwan S, Mansor S, McIlleron H, Miller R, Molyneux M, Mwenechanya J, Navaratnam V, Nosten F, Olliaro P, Pang L, Ribeiro I, Tembo M, van Vugt M, Ward S, Weerasuriya K, Win K, White NJ.

    PLoS Med. 2006 Nov;3(11):e444.

    PMID:
    17132053
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Absence of time-dependent artesunate pharmacokinetics in healthy subjects during 5-day oral administration.

    Diem Thuy LT, Ngoc Hung L, Danh PT, Na-Bangchang K.

    Eur J Clin Pharmacol. 2008 Oct;64(10):993-8. Epub 2008 Jul 4.

    PMID:
    18600318
    [PubMed - indexed for MEDLINE]
    5.

    The multiple-dosing pharmacokinetics of artemether, artesunate, and their metabolite dihydroartemisinin in rats.

    Xing J, Bai KH, Liu T, Wang RL, Zhang LF, Zhang SQ.

    Xenobiotica. 2011 Mar;41(3):252-8. Epub 2010 Dec 22.

    PMID:
    21175296
    [PubMed - indexed for MEDLINE]
    6.

    Pharmacokinetics of artesunate following oral and rectal administration in healthy Sudanese volunteers.

    Awad MI, Eltayeb IB, Baraka OZ, Behrens RH, Alkadru AM.

    Trop Doct. 2004 Jul;34(3):132-5.

    PMID:
    15267037
    [PubMed - indexed for MEDLINE]
    7.

    Pharmacokinetics of artemether and dihydroartemisinin in healthy Pakistani male volunteers treated with artemether-lumefantrine.

    Ali S, Najmi MH, Tarning J, Lindegardh N.

    Malar J. 2010 Oct 11;9:275.

    PMID:
    20932349
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    8.

    Pharmacokinetics and pharmacodynamics of artesunate and dihydroartemisinin following oral treatment in pregnant women with asymptomatic Plasmodium falciparum infections in Kinshasa DRC.

    Onyamboko MA, Meshnick SR, Fleckenstein L, Koch MA, Atibu J, Lokomba V, Douoguih M, Hemingway-Foday J, Wesche D, Ryder RW, Bose C, Wright LL, Tshefu AK, Capparelli EV.

    Malar J. 2011 Feb 28;10:49.

    PMID:
    21352601
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    9.

    Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration.

    Morris CA, Duparc S, Borghini-Fuhrer I, Jung D, Shin CS, Fleckenstein L.

    Malar J. 2011 Sep 13;10:263. Review.

    PMID:
    21914160
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    10.

    The pharmacokinetics of oral dihydroartemisinin and artesunate in healthy Thai volunteers.

    Na-Bangchang K, Krudsood S, Silachamroon U, Molunto P, Tasanor O, Chalermrut K, Tangpukdee N, Matangkasombut O, Kano S, Looareesuwan S.

    Southeast Asian J Trop Med Public Health. 2004 Sep;35(3):575-82.

    PMID:
    15689069
    [PubMed - indexed for MEDLINE]
    11.

    Pharmacokinetics of artesunate in the domestic pig.

    Sinou V, Taudon N, Mosnier J, Aglioni C, Bressolle FM, Parzy D.

    J Antimicrob Chemother. 2008 Sep;62(3):566-74. Epub 2008 Jun 16.

    PMID:
    18559353
    [PubMed - indexed for MEDLINE]
    Free Article
    12.

    Pharmacokinetic profiles of artesunate after single intravenous doses at 0.5, 1, 2, 4, and 8 mg/kg in healthy volunteers: a phase I study.

    Li Q, Cantilena LR, Leary KJ, Saviolakis GA, Miller RS, Melendez V, Weina PJ.

    Am J Trop Med Hyg. 2009 Oct;81(4):615-21.

    PMID:
    19815876
    [PubMed - indexed for MEDLINE]
    Free Article
    13.

    Pharmacokinetic parameters of artesunate and dihydroartemisinin in rats infected with Fasciola hepatica.

    Keiser J, Gruyer MS, Perrottet N, Zanolari B, Mercier T, Decosterd L.

    J Antimicrob Chemother. 2009 Mar;63(3):543-9. Epub 2009 Jan 24.

    PMID:
    19168863
    [PubMed - indexed for MEDLINE]
    Free Article
    14.

    Multiple dose study of interactions between artesunate and artemisinin in healthy volunteers.

    Zhang SQ, Hai TN, Ilett KF, Huong DX, Davis TM, Ashton M.

    Br J Clin Pharmacol. 2001 Oct;52(4):377-85.

    PMID:
    11678781
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    15.

    Pharmacokinetics of dihydroartemisinin in Artekin tablets for single and repeated dosing in Chinese healthy volunteers.

    Hong X, Liu CH, Huang XT, Huang TL, Ye SM, Ou WP, Wang NS, Mi SQ.

    Biopharm Drug Dispos. 2008 May;29(4):237-44.

    PMID:
    18350560
    [PubMed - indexed for MEDLINE]
    16.

    Pharmacokinetics and ex vivo antimalarial activity of artesunate-azithromycin in healthy volunteers.

    Chinh NT, Quang NN, Anh CX, Thanh NX, Dai B, Birrell GW, Chavchich M, Edstein MD.

    Antimicrob Agents Chemother. 2011 Sep;55(9):4412-5. Epub 2011 Jul 5.

    PMID:
    21730120
    [PubMed - indexed for MEDLINE]
    17.

    Disposition of artesunate and dihydroartemisinin after administration of artesunate suppositories in children from Papua New Guinea with uncomplicated malaria.

    Karunajeewa HA, Ilett KF, Dufall K, Kemiki A, Bockarie M, Alpers MP, Barrett PH, Vicini P, Davis TM.

    Antimicrob Agents Chemother. 2004 Aug;48(8):2966-72.

    PMID:
    15273107
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.

    A simplified liquid chromatography-mass spectrometry assay for artesunate and dihydroartemisinin, its metabolite, in human plasma.

    Teja-Isavadharm P, Siriyanonda D, Siripokasupkul R, Apinan R, Chanarat N, Lim A, Wannaying S, Saunders D, Fukuda MM, Miller RS, Weina PJ, Meléndez V.

    Molecules. 2010 Dec 1;15(12):8747-68.

    PMID:
    21124272
    [PubMed - indexed for MEDLINE]
    19.

    Pharmacokinetics of dihydroartemisinin following oral artesunate treatment of pregnant women with acute uncomplicated falciparum malaria.

    McGready R, Stepniewska K, Ward SA, Cho T, Gilveray G, Looareesuwan S, White NJ, Nosten F.

    Eur J Clin Pharmacol. 2006 May;62(5):367-71. Epub 2006 Mar 22.

    PMID:
    16552504
    [PubMed - indexed for MEDLINE]
    20.

    Pharmacokinetics and tolerability of artesunate and amodiaquine alone and in combination in healthy volunteers.

    Orrell C, Little F, Smith P, Folb P, Taylor W, Olliaro P, Barnes KI.

    Eur J Clin Pharmacol. 2008 Jul;64(7):683-90. Epub 2008 Apr 16.

    PMID:
    18415093
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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