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    Results: 1 to 20 of 100

    1.

    Matrix metalloproteinase 28, a novel matrix metalloproteinase, is constitutively expressed in human intervertebral disc tissue and is present in matrix of more degenerated discs.

    Gruber HE, Ingram JA, Hoelscher GL, Zinchenko N, Norton HJ, Hanley EN Jr.

    Arthritis Res Ther. 2009;11(6):R184. Epub 2009 Dec 9.

    PMID:
    20003223
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Matrix metalloproteinase expression levels suggest distinct enzyme roles during lumbar disc herniation and degeneration.

    Bachmeier BE, Nerlich A, Mittermaier N, Weiler C, Lumenta C, Wuertz K, Boos N.

    Eur Spine J. 2009 Nov;18(11):1573-86. Epub 2009 May 23.

    PMID:
    19466462
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    2002 SSE Award Competition in Basic Science: expression of major matrix metalloproteinases is associated with intervertebral disc degradation and resorption.

    Weiler C, Nerlich AG, Zipperer J, Bachmeier BE, Boos N.

    Eur Spine J. 2002 Aug;11(4):308-20. Epub 2002 Jul 9.

    PMID:
    12193991
    [PubMed - indexed for MEDLINE]
    4.

    Matrix metalloproteinases and aggrecanase: their role in disorders of the human intervertebral disc.

    Roberts S, Caterson B, Menage J, Evans EH, Jaffray DC, Eisenstein SM.

    Spine (Phila Pa 1976). 2000 Dec 1;25(23):3005-13.

    PMID:
    11145811
    [PubMed - indexed for MEDLINE]
    5.

    Human MMP28 expression is unresponsive to inflammatory stimuli and does not correlate to the grade of intervertebral disc degeneration.

    Klawitter M, Quero L, Bertolo A, Mehr M, Stoyanov J, Nerlich AG, Klasen J, Aebli N, Boos N, Wuertz K.

    J Negat Results Biomed. 2011 Jul 29;10:9.

    PMID:
    21801383
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    Immunolocalization of MMP-19 in the human intervertebral disc: implications for disc aging and degeneration.

    Gruber HE, Ingram JA, Hanley EN Jr.

    Biotech Histochem. 2005 May-Aug;80(3-4):157-62.

    PMID:
    16298901
    [PubMed - indexed for MEDLINE]
    7.

    Annulus cells from more degenerated human discs show modified gene expression in 3D culture compared with expression in cells from healthier discs.

    Gruber HE, Hoelscher GL, Hanley EN Jr.

    Spine J. 2010 Aug;10(8):721-7.

    PMID:
    20650410
    [PubMed - indexed for MEDLINE]
    8.

    Immunohistochemical study of matrix metalloproteinase-3 and tissue inhibitor of metalloproteinase-1 human intervertebral discs.

    Kanemoto M, Hukuda S, Komiya Y, Katsuura A, Nishioka J.

    Spine (Phila Pa 1976). 1996 Jan 1;21(1):1-8.

    PMID:
    9122749
    [PubMed - indexed for MEDLINE]
    9.

    Matrix metalloproteinases: the clue to intervertebral disc degeneration?

    Goupille P, Jayson MI, Valat JP, Freemont AJ.

    Spine (Phila Pa 1976). 1998 Jul 15;23(14):1612-26. Review.

    PMID:
    9682320
    [PubMed - indexed for MEDLINE]
    10.

    Expression profiling of metalloproteinases and their inhibitors in synovium and cartilage.

    Davidson RK, Waters JG, Kevorkian L, Darrah C, Cooper A, Donell ST, Clark IM.

    Arthritis Res Ther. 2006;8(4):R124.

    PMID:
    16859525
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    11.

    Human disc degeneration is associated with increased MMP 7 expression.

    Le Maitre CL, Freemont AJ, Hoyland JA.

    Biotech Histochem. 2006 Jul-Dec;81(4-6):125-31.

    PMID:
    17129995
    [PubMed - indexed for MEDLINE]
    12.

    Asporin, a susceptibility gene in osteoarthritis, is expressed at higher levels in the more degenerate human intervertebral disc.

    Gruber HE, Ingram JA, Hoelscher GL, Zinchenko N, Hanley EN Jr, Sun Y.

    Arthritis Res Ther. 2009;11(2):R47. Epub 2009 Mar 27.

    PMID:
    19327154
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    13.

    Matrix metalloproteinases in the human intervertebral disc: role in disc degeneration and scoliosis.

    Crean JK, Roberts S, Jaffray DC, Eisenstein SM, Duance VC.

    Spine (Phila Pa 1976). 1997 Dec 15;22(24):2877-84.

    PMID:
    9431623
    [PubMed - indexed for MEDLINE]
    14.

    Matrix metalloproteinase-3 production by human degenerated intervertebral disc.

    Nemoto O, Yamagishi M, Yamada H, Kikuchi T, Takaishi H.

    J Spinal Disord. 1997 Dec;10(6):493-8.

    PMID:
    9438814
    [PubMed - indexed for MEDLINE]
    15.

    Effects of hydrostatic pressure on matrix synthesis and matrix metalloproteinase production in the human lumbar intervertebral disc.

    Handa T, Ishihara H, Ohshima H, Osada R, Tsuji H, Obata K.

    Spine (Phila Pa 1976). 1997 May 15;22(10):1085-91.

    PMID:
    9160466
    [PubMed - indexed for MEDLINE]
    16.

    Plasmin-matrix metalloproteinase cascades in spinal response to an experimental disc lesion in pig.

    Salo J, Mackiewicz Z, Indahl A, Konttinen YT, Holm AK, Sukura A, Holm S.

    Spine (Phila Pa 1976). 2008 Apr 15;33(8):839-44.

    PMID:
    18404101
    [PubMed - indexed for MEDLINE]
    17.

    Accelerated intervertebral disc degeneration in scoliosis versus physiological ageing develops against a background of enhanced anabolic gene expression.

    Bertram H, Steck E, Zimmerman G, Chen B, Carstens C, Nerlich A, Richter W.

    Biochem Biophys Res Commun. 2006 Apr 14;342(3):963-72.

    PMID:
    16598853
    [PubMed - indexed for MEDLINE]
    18.

    Microarray analysis of laser capture microdissected-anulus cells from the human intervertebral disc.

    Gruber HE, Mougeot JL, Hoelscher G, Ingram JA, Hanley EN Jr.

    Spine (Phila Pa 1976). 2007 May 15;32(11):1181-7.

    PMID:
    17495774
    [PubMed - indexed for MEDLINE]
    19.

    Comparative gene expression profiling of normal and degenerative discs: analysis of a rabbit annular laceration model.

    Anderson DG, Izzo MW, Hall DJ, Vaccaro AR, Hilibrand A, Arnold W, Tuan RS, Albert TJ.

    Spine (Phila Pa 1976). 2002 Jun 15;27(12):1291-6.

    PMID:
    12065976
    [PubMed - indexed for MEDLINE]

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