PubMed

Generalized immune activation as a direct result of activated CD4+ T cell killing.

Marques R, Williams A, Eksmond U, Wullaert A, Killeen N, Pasparakis M, Kioussis D, Kassiotis G.

J Biol. 2009;8(10):93. Epub .PMID: 19943952 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Distinct mechanisms of CD4+ and CD8+ T-cell activation and bystander apoptosis induced by human immunodeficiency virus type 1 virions.

Holm GH, Gabuzda D.

J Virol. 2005 May;79(10):6299-311.PMID: 15858014 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice.

Brainard DM, Seung E, Frahm N, Cariappa A, Bailey CC, Hart WK, Shin HS, Brooks SF, Knight HL, Eichbaum Q, Yang YG, Sykes M, Walker BD, Freeman GJ, Pillai S, Westmoreland SV, Brander C, Luster AD, Tager AM.

J Virol. 2009 Jul;83(14):7305-21. Epub 2009 May 6.PMID: 19420076 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Life and death as a T lymphocyte: from immune protection to HIV pathogenesis.

Vrisekoop N, Mandl JN, Germain RN.

J Biol. 2009;8(10):91. Epub . Review.PMID: 19951397 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load.

Sousa AE, Carneiro J, Meier-Schellersheim M, Grossman Z, Victorino RM.

J Immunol. 2002 Sep 15;169(6):3400-6.PMID: 12218162 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Apoptotic killing of CD4+ T lymphocytes in HIV-1-infected PHA-stimulated PBL cultures is mediated by CD8+ LAK cells.

Wang L, Klimpel GR, Planas JM, Li H, Cloyd MW.

Virology. 1998 Feb 15;241(2):169-80.PMID: 9499792 [PubMed - indexed for MEDLINE]Related citations

Turnover of lymphocytes and conceptual paradigms in HIV infection.

Silvestri G, Feinberg MB.

J Clin Invest. 2003 Sep;112(6):821-4.PMID: 12975464 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Loss of CD127 expression links immune activation and CD4(+) T cell loss in HIV infection.

Kiazyk SA, Fowke KR.

Trends Microbiol. 2008 Dec;16(12):567-73. Epub 2008 Oct 27.PMID: 18964017 [PubMed - indexed for MEDLINE]Related citations

Persistent immune activation in HIV-1 infection is associated with progression to AIDS.

Hazenberg MD, Otto SA, van Benthem BH, Roos MT, Coutinho RA, Lange JM, Hamann D, Prins M, Miedema F.

AIDS. 2003 Sep 5;17(13):1881-8.PMID: 12960820 [PubMed - indexed for MEDLINE]Related citations

Preserved central memory and activated effector memory CD4+ T-cell subsets in human immunodeficiency virus controllers: an ANRS EP36 study.

Potter SJ, Lacabaratz C, Lambotte O, Perez-Patrigeon S, Vingert B, Sinet M, Colle JH, Urrutia A, Scott-Algara D, Boufassa F, Delfraissy JF, Thèze J, Venet A, Chakrabarti LA.

J Virol. 2007 Dec;81(24):13904-15. Epub 2007 Oct 10.PMID: 17928341 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Programmed cell death in peripheral lymphocytes from HIV-infected persons: increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression.

Gougeon ML, Lecoeur H, Dulioust A, Enouf MG, Crouvoiser M, Goujard C, Debord T, Montagnier L.

J Immunol. 1996 May 1;156(9):3509-20.PMID: 8617980 [PubMed - indexed for MEDLINE]Related citations

Differential upregulation of CD38 on different T-cell subsets may influence the ability to reconstitute CD4+ T cells under successful highly active antiretroviral therapy.

Benito JM, López M, Lozano S, Ballesteros C, Martinez P, González-Lahoz J, Soriano V.

J Acquir Immune Defic Syndr. 2005 Apr 1;38(4):373-81.PMID: 15764953 [PubMed - indexed for MEDLINE]Related citations

Loss of CD127 expression defines an expansion of effector CD8+ T cells in HIV-infected individuals.

Paiardini M, Cervasi B, Albrecht H, Muthukumar A, Dunham R, Gordon S, Radziewicz H, Piedimonte G, Magnani M, Montroni M, Kaech SM, Weintrob A, Altman JD, Sodora DL, Feinberg MB, Silvestri G.

J Immunol. 2005 Mar 1;174(5):2900-9.PMID: 15728501 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Human immunodeficiency virus type 1 strains R5 and X4 induce different pathogenic effects in hu-PBL-SCID mice, depending on the state of activation/differentiation of human target cells at the time of primary infection.

Fais S, Lapenta C, Santini SM, Spada M, Parlato S, Logozzi M, Rizza P, Belardelli F.

J Virol. 1999 Aug;73(8):6453-9.PMID: 10400739 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Antiviral CD4 and CD8 T-cell memory: differences in the size of the response and activation requirements.

Whitmire JK, Murali-Krishna K, Altman J, Ahmed R.

Philos Trans R Soc Lond B Biol Sci. 2000 Mar 29;355(1395):373-9.PMID: 10794058 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Glucocorticoids rescue CD4+ T lymphocytes from activation-induced apoptosis triggered by HIV-1: implications for pathogenesis and therapy.

Lu W, Salerno-Goncalves R, Yuan J, Sylvie D, Han DS, Andrieu JM.

AIDS. 1995 Jan;9(1):35-42.PMID: 7893439 [PubMed - indexed for MEDLINE]Related citations

Disrupting T-cell homeostasis: how HIV-1 infection causes disease.

Douek DC.

AIDS Rev. 2003 Jul-Sep;5(3):172-7. Review.PMID: 14598566 [PubMed - indexed for MEDLINE]Related citations

Antiretroviral therapy corrects HIV-1-induced expansion of CD8+ CD45RA+ CD2-) CD11a(bright) activated T cells.

Yin L, Rodriguez CA, Hou W, Potter O, Caplan MJ, Goodenow MM, Sleasman JW.

J Allergy Clin Immunol. 2008 Jul;122(1):166-72, 172.e1-2. Epub 2008 Jun 9.PMID: 18538835 [PubMed - indexed for MEDLINE]Related citations

Intestinal double-positive CD4+CD8+ T cells are highly activated memory cells with an increased capacity to produce cytokines.

Pahar B, Lackner AA, Veazey RS.

Eur J Immunol. 2006 Mar;36(3):583-92.PMID: 16506292 [PubMed - indexed for MEDLINE]Related citations

Naïve and memory CD4+ T cells and T cell activation markers in HIV-1 infected children on HAART.

Resino S, Navarro J, Bellón JM, Gurbindo D, León JA, Muñoz-Fernández MA.

Clin Exp Immunol. 2001 Aug;125(2):266-73.PMID: 11529919 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations