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    Results: 1 to 20 of 258

    1.

    BU-32: a novel proteasome inhibitor for breast cancer.

    Agyin JK, Santhamma B, Nair HB, Roy SS, Tekmal RR.

    Breast Cancer Res. 2009;11(5):R74. Epub .

    PMID:
    19821999
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    A proteasome inhibitor, bortezomib, inhibits breast cancer growth and reduces osteolysis by downregulating metastatic genes.

    Jones MD, Liu JC, Barthel TK, Hussain S, Lovria E, Cheng D, Schoonmaker JA, Mulay S, Ayers DC, Bouxsein ML, Stein GS, Mukherjee S, Lian JB.

    Clin Cancer Res. 2010 Oct 15;16(20):4978-89. Epub 2010 Sep 15.

    PMID:
    20843837
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.
    4.

    Proteasome inhibition sensitizes non-small-cell lung cancer to gemcitabine-induced apoptosis.

    Denlinger CE, Rundall BK, Keller MD, Jones DR.

    Ann Thorac Surg. 2004 Oct;78(4):1207-14; discussion 1207-14.

    PMID:
    15464472
    [PubMed - indexed for MEDLINE]
    5.

    Differential sensitivity of breast cancer and melanoma cells to proteasome inhibitor Velcade.

    Yerlikaya A, Erin N.

    Int J Mol Med. 2008 Dec;22(6):817-23.

    PMID:
    19020781
    [PubMed - indexed for MEDLINE]
    6.

    Cyclin D1 overexpression and response to bortezomib treatment in a breast cancer model.

    Ishii Y, Pirkmaier A, Alvarez JV, Frank DA, Keselman I, Logothetis D, Mandeli J, O'Connell MJ, Waxman S, Germain D.

    J Natl Cancer Inst. 2006 Sep 6;98(17):1238-47.

    PMID:
    16954476
    [PubMed - indexed for MEDLINE]
    Free Article
    7.

    26S proteasome inhibition induces apoptosis and limits growth of human pancreatic cancer.

    Shah SA, Potter MW, McDade TP, Ricciardi R, Perugini RA, Elliott PJ, Adams J, Callery MP.

    J Cell Biochem. 2001 Apr 2-27;82(1):110-22.

    PMID:
    11400168
    [PubMed - indexed for MEDLINE]
    9.

    Bortezomib (PS-341, Velcade) increases the efficacy of trastuzumab (Herceptin) in HER-2-positive breast cancer cells in a synergistic manner.

    Cardoso F, Durbecq V, Laes JF, Badran B, Lagneaux L, Bex F, Desmedt C, Willard-Gallo K, Ross JS, Burny A, Piccart M, Sotiriou C.

    Mol Cancer Ther. 2006 Dec;5(12):3042-51. Epub 2006 Dec 5.

    PMID:
    17148762
    [PubMed - indexed for MEDLINE]
    Free Article
    10.

    Effects of the proteasome inhibitor bortezomib alone and in combination with chemotherapeutic agents in gastric cancer cell lines.

    Bae SH, Ryoo HM, Kim MK, Lee KH, Sin JI, Hyun MS.

    Oncol Rep. 2008 Apr;19(4):1027-32.

    PMID:
    18357392
    [PubMed - indexed for MEDLINE]
    11.

    Intracellular inhibitory effects of Velcade correlate with morphoproteomic expression of phosphorylated-nuclear factor-kappaB and p53 in breast cancer cell lines.

    Lun M, Zhang PL, Siegelmann-Danieli N, Blasick TM, Brown RE.

    Ann Clin Lab Sci. 2005 Winter;35(1):15-24.

    PMID:
    15830705
    [PubMed - indexed for MEDLINE]
    12.

    Discovery of a novel proteasome inhibitor selective for cancer cells over non-transformed cells.

    Kazi A, Lawrence H, Guida WC, McLaughlin ML, Springett GM, Berndt N, Yip RM, Sebti SM.

    Cell Cycle. 2009 Jun 15;8(12):1940-51. Epub 2009 Jun 20.

    PMID:
    19471122
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    13.

    Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-kappaB.

    Russo SM, Tepper JE, Baldwin AS Jr, Liu R, Adams J, Elliott P, Cusack JC Jr.

    Int J Radiat Oncol Biol Phys. 2001 May 1;50(1):183-93.

    PMID:
    11316563
    [PubMed - indexed for MEDLINE]
    14.

    CEP-18770: A novel, orally active proteasome inhibitor with a tumor-selective pharmacologic profile competitive with bortezomib.

    Piva R, Ruggeri B, Williams M, Costa G, Tamagno I, Ferrero D, Giai V, Coscia M, Peola S, Massaia M, Pezzoni G, Allievi C, Pescalli N, Cassin M, di Giovine S, Nicoli P, de Feudis P, Strepponi I, Roato I, Ferracini R, Bussolati B, Camussi G, Jones-Bolin S, Hunter K, Zhao H, Neri A, Palumbo A, Berkers C, Ovaa H, Bernareggi A, Inghirami G.

    Blood. 2008 Mar 1;111(5):2765-75. Epub 2007 Dec 5.

    PMID:
    18057228
    [PubMed - indexed for MEDLINE]
    Free Article
    16.

    Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors.

    Zhu H, Zhang L, Dong F, Guo W, Wu S, Teraishi F, Davis JJ, Chiao PJ, Fang B.

    Oncogene. 2005 Jul 21;24(31):4993-9.

    PMID:
    15824729
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    17.

    Proteasome inhibitors induce a p38 mitogen-activated protein kinase (MAPK)-dependent anti-apoptotic program involving MAPK phosphatase-1 and Akt in models of breast cancer.

    Shi YY, Small GW, Orlowski RZ.

    Breast Cancer Res Treat. 2006 Nov;100(1):33-47. Epub 2006 Jun 29.

    PMID:
    16807678
    [PubMed - indexed for MEDLINE]
    18.

    The proteasome inhibitor bortezomib enhances the activity of docetaxel in orthotopic human pancreatic tumor xenografts.

    Nawrocki ST, Sweeney-Gotsch B, Takamori R, McConkey DJ.

    Mol Cancer Ther. 2004 Jan;3(1):59-70. Erratum in: Mol Cancer Ther. 2009 Feb;8(2):479.

    PMID:
    14749476
    [PubMed - indexed for MEDLINE]
    Free Article
    19.

    Effect of noncompetitive proteasome inhibition on bortezomib resistance.

    Li X, Wood TE, Sprangers R, Jansen G, Franke NE, Mao X, Wang X, Zhang Y, Verbrugge SE, Adomat H, Li ZH, Trudel S, Chen C, Religa TL, Jamal N, Messner H, Cloos J, Rose DR, Navon A, Guns E, Batey RA, Kay LE, Schimmer AD.

    J Natl Cancer Inst. 2010 Jul 21;102(14):1069-82. Epub 2010 May 26.

    PMID:
    20505154
    [PubMed - indexed for MEDLINE]
    Free Article
    20.

    Bortezomib (Velcade) induces p27Kip1 expression through S-phase kinase protein 2 degradation in colorectal cancer.

    Uddin S, Ahmed M, Bavi P, El-Sayed R, Al-Sanea N, AbdulJabbar A, Ashari LH, Alhomoud S, Al-Dayel F, Hussain AR, Al-Kuraya KS.

    Cancer Res. 2008 May 1;68(9):3379-88.

    PMID:
    18451165
    [PubMed - indexed for MEDLINE]
    Free Article

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