PubMed

Binding site of ABC transporter homology models confirmed by ABCB1 crystal structure.

Ravna AW, Sylte I, Sager G.

Theor Biol Med Model. 2009 Sep 4;6:20.PMID: 19732422 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Molecular model of the outward facing state of the human P-glycoprotein (ABCB1), and comparison to a model of the human MRP5 (ABCC5).

Ravna AW, Sylte I, Sager G.

Theor Biol Med Model. 2007 Sep 6;4:33.PMID: 17803828 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Molecular model of the outward facing state of the human multidrug resistance protein 4 (MRP4/ABCC4).

Ravna AW, Sager G.

Bioorg Med Chem Lett. 2008 Jun 15;18(12):3481-3. Epub 2008 May 16.PMID: 18513968 [PubMed - indexed for MEDLINE]Related citations

An atomic detail model for the human ATP binding cassette transporter P-glycoprotein derived from disulfide cross-linking and homology modeling.

Stenham DR, Campbell JD, Sansom MS, Higgins CF, Kerr ID, Linton KJ.

FASEB J. 2003 Dec;17(15):2287-9. Epub 2003 Oct 16.PMID: 14563687 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

A structural model for the open conformation of the mdr1 P-glycoprotein based on the MsbA crystal structure.

Seigneuret M, Garnier-Suillerot A.

J Biol Chem. 2003 Aug 8;278(32):30115-24. Epub 2003 May 30.PMID: 12777401 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Identification of putative steroid-binding sites in human ABCB1 and ABCG2.

Mares-Sámano S, Badhan R, Penny J.

Eur J Med Chem. 2009 Sep;44(9):3601-11. Epub 2009 Mar 6.PMID: 19303670 [PubMed - indexed for MEDLINE]Related citations

New light on multidrug binding by an ATP-binding-cassette transporter.

Shilling RA, Venter H, Velamakanni S, Bapna A, Woebking B, Shahi S, van Veen HW.

Trends Pharmacol Sci. 2006 Apr;27(4):195-203. Epub 2006 Mar 20. Review.PMID: 16545467 [PubMed - indexed for MEDLINE]Related citations

A new structural model for P-glycoprotein.

Jones PM, George AM.

J Membr Biol. 1998 Nov 15;166(2):133-47.PMID: 9841738 [PubMed - indexed for MEDLINE]Related citations

Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters.

Chang G, Roth CB.

Science. 2001 Sep 7;293(5536):1793-800. Retraction in: Chang G, Roth CB, Reyes CL, Pornillos O, Chen YJ, Chen AP. Science. 2006 Dec 22;314(5807):1875. PMID: 11546864 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Structure of the human multidrug resistance protein 1 nucleotide binding domain 1 bound to Mg2+/ATP reveals a non-productive catalytic site.

Ramaen O, Leulliot N, Sizun C, Ulryck N, Pamlard O, Lallemand JY, Tilbeurgh H, Jacquet E.

J Mol Biol. 2006 Jun 16;359(4):940-9. Epub 2006 May 2.PMID: 16697012 [PubMed - indexed for MEDLINE]Related citations

A new dimer interface for an ABC transporter.

Shilling RA, Balakrishnan L, Shahi S, Venter H, van Veen HW.

Int J Antimicrob Agents. 2003 Sep;22(3):200-4.PMID: 13678821 [PubMed - indexed for MEDLINE]Related citations

Molecular basis of multidrug transport by ABC transporters.

Seeger MA, van Veen HW.

Biochim Biophys Acta. 2009 May;1794(5):725-37. Epub 2008 Dec 24. Review.PMID: 19135557 [PubMed - indexed for MEDLINE]Related citations

The crystal structure of the MJ0796 ATP-binding cassette. Implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter.

Yuan YR, Blecker S, Martsinkevich O, Millen L, Thomas PJ, Hunt JF.

J Biol Chem. 2001 Aug 24;276(34):32313-21. Epub 2001 Jun 11.PMID: 11402022 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Understanding polyspecificity of multidrug ABC transporters: closing in on the gaps in ABCB1.

Gutmann DA, Ward A, Urbatsch IL, Chang G, van Veen HW.

Trends Biochem Sci. 2010 Jan;35(1):36-42. Epub 2009 Oct 12. Review.PMID: 19819701 [PubMed - indexed for MEDLINE]Related citations

The conserved tyrosine residues 401 and 1044 in ATP sites of human P-glycoprotein are critical for ATP binding and hydrolysis: evidence for a conserved subdomain, the A-loop in the ATP-binding cassette.

Kim IW, Peng XH, Sauna ZE, FitzGerald PC, Xia D, Müller M, Nandigama K, Ambudkar SV.

Biochemistry. 2006 Jun 20;45(24):7605-16.PMID: 16768456 [PubMed - indexed for MEDLINE]Related citations

Structure of an ABC transporter in complex with its binding protein.

Hollenstein K, Frei DC, Locher KP.

Nature. 2007 Mar 8;446(7132):213-6. Epub 2007 Feb 25.PMID: 17322901 [PubMed - indexed for MEDLINE]Related citations

The Q-loop disengages from the first intracellular loop during the catalytic cycle of the multidrug ABC transporter BmrA.

Dalmas O, Orelle C, Foucher AE, Geourjon C, Crouzy S, Di Pietro A, Jault JM.

J Biol Chem. 2005 Nov 4;280(44):36857-64. Epub 2005 Aug 17.PMID: 16107340 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Structure of MsbA from Vibrio cholera: a multidrug resistance ABC transporter homolog in a closed conformation.

Chang G.

J Mol Biol. 2003 Jul 4;330(2):419-30. Retraction in: Chang G. J Mol Biol. 2007 Jun 1;369(2):596. PMID: 12823979 [PubMed - indexed for MEDLINE]Related citations

Molecular modeling studies of ABC transporters involved in multidrug resistance.

Ravna AW, Sager G.

Mini Rev Med Chem. 2009 Feb;9(2):186-93. Review.PMID: 19200023 [PubMed - indexed for MEDLINE]Related citations

ATP modulates subunit-subunit interactions in an ATP-binding cassette transporter (MalFGK2) determined by site-directed chemical cross-linking.

Hunke S, Mourez M, Jehanno M, Dassa E, Schneider E.

J Biol Chem. 2000 May 19;275(20):15526-34.PMID: 10809785 [PubMed - indexed for MEDLINE]Free ArticleRelated citations