Warning: The NCBI web site requires JavaScript to function. more...
Huntington's disease: the case for genetic modifiers.
Gusella JF, MacDonald ME.
Genome Med. 2009 Aug 21;1(8):80.
Related citations
Genetic criteria for Huntington's disease pathogenesis.
Gusella JF, Macdonald M.
Brain Res Bull. 2007 Apr 30;72(2-3):78-82. Epub 2006 Nov 15.
Protein Interactions and Target Discovery in Huntington’s Disease.
Miller JP, Hughes RE.
In: Lo DC, Hughes RE, editors. Neurobiology of Huntington's Disease: Applications to Drug Discovery. Boca Raton (FL): CRC Press; 2011. Chapter 3.
Huntington's Disease: Advocacy Driving Science.
Wexler NS.
Annu Rev Med. 2012 Feb 18;63:1-22.
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.
[No authors listed]
Cell. 1993 Mar 26;72(6):971-83.
Replicating Huntington's disease phenotype in experimental animals.
Brouillet E, Condé F, Beal MF, Hantraye P.
Prog Neurobiol. 1999 Dec;59(5):427-68. Review.
Location cloning strategy for characterizing genetic defects in Huntington's disease and Alzheimer's disease.
Gusella JF.
FASEB J. 1989 Jul;3(9):2036-41. Review.
The Huntington's disease-like syndromes: what to consider in patients with a negative Huntington's disease gene test.
Schneider SA, Walker RH, Bhatia KP.
Nat Clin Pract Neurol. 2007 Sep;3(9):517-25. Review.
Rationale for intrastriatal grafting of striatal neuroblasts in patients with Huntington's disease.
Peschanski M, Cesaro P, Hantraye P.
Neuroscience. 1995 Sep;68(2):273-85. Review.
Genetic background modulates behavioral impairments in R6/2 mice and suggests a role for dominant genetic modifiers in Huntington's disease pathogenesis.
Cowin RM, Bui N, Graham D, Green JR, Yuva-Paylor LA, Weiss A, Paylor R.
Mamm Genome. 2012 Jan 31. [Epub ahead of print]
Neuropathological diagnosis and CAG repeat expansion in Huntington's disease.
Xuereb JH, MacMillan JC, Snell R, Davies P, Harper PS.
J Neurol Neurosurg Psychiatry. 1996 Jan;60(1):78-81.
[Huntington's disease--advances in gene mapping].
Nakamura S.
Nihon Rinsho. 1993 Sep;51(9):2481-7. Review. Japanese.
Molecular genetics of Huntington's disease.
Gusella JF, MacDonald ME, Ambrose CM, Duyao MP.
Arch Neurol. 1993 Nov;50(11):1157-63. Review.
An ovine transgenic Huntington's disease model.
Jacobsen JC, Bawden CS, Rudiger SR, McLaughlan CJ, Reid SJ, Waldvogel HJ, MacDonald ME, Gusella JF, Walker SK, Kelly JM, Webb GC, Faull RL, Rees MI, Snell RG.
Hum Mol Genet. 2010 May 15;19(10):1873-82. Epub 2010 Feb 13.
Huntington's disease: from molecular pathogenesis to clinical treatment.
Ross CA, Tabrizi SJ.
Lancet Neurol. 2011 Jan;10(1):83-98. Review.
[Etiology and pathogenesis of Parkinson's disease: from mitochondrial dysfunctions to familial Parkinson's disease].
Hattori N.
Rinsho Shinkeigaku. 2004 Apr-May;44(4-5):241-62. Review. Japanese.
A cosmid contig and high resolution restriction map of the 2 megabase region containing the Huntington's disease gene.
Baxendale S, MacDonald ME, Mott R, Francis F, Lin C, Kirby SF, James M, Zehetner G, Hummerich H, Valdes J, et al.
Nat Genet. 1993 Jun;4(2):181-6.
A highly polymorphic locus very tightly linked to the Huntington's disease gene.
Wasmuth JJ, Hewitt J, Smith B, Allard D, Haines JL, Skarecky D, Partlow E, Hayden MR.
Nature. 1988 Apr 21;332(6166):734-6.
Familial aggregation of psychotic symptoms in Huntington's disease.
Tsuang D, Almqvist EW, Lipe H, Strgar F, DiGiacomo L, Hoff D, Eugenio C, Hayden MR, Bird TD.
Am J Psychiatry. 2000 Dec;157(12):1955-9.
Mutant huntingtin activates Nrf2-responsive genes and impairs dopamine synthesis in a PC12 model of Huntington's disease.
van Roon-Mom WM, Pepers BA, 't Hoen PA, Verwijmeren CA, den Dunnen JT, Dorsman JC, van Ommen GB.
BMC Mol Biol. 2008 Oct 9;9:84.
Filter your results:
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on