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The safety and efficacy of zidovudine (AZT) in the treatment of subjects with mildly symptomatic human immunodeficiency virus type 1 (HIV) infection. A double-blind, placebo-controlled trial. The AIDS Clinical Trials Group.

Fischl MA, Richman DD, Hansen N, Collier AC, Carey JT, Para MF, Hardy WD, Dolin R, Powderly WG, Allan JD, et al.

Ann Intern Med. 1990 May 15;112(10):727-37.PMID: 1970466 [PubMed - indexed for MEDLINE]Related articles

Zidovudine twice daily in asymptomatic subjects with HIV infection and a high risk of progression to AIDS: a randomized, double-blind placebo-controlled study. The European-Australian Collaborative Group (Study 017)

Mulder JW, Cooper DA, Mathiesen L, Sandström E, Clumeck N, Gatell JM, French M, Donovan B, Gray F, Yeo JM, et al.

AIDS. 1994 Mar;8(3):313-21. Erratum in: AIDS 1994 Jun;8(6):following 859. PMID: 7913326 [PubMed - indexed for MEDLINE]Related articles

Safety and efficacy of thymopentin in zidovudine (AZT)-treated asymptomatic HIV-infected subjects with 200-500 CD4 cells/mm3: a double-blind placebo-controlled trial.

Goldstein G, Conant MA, Beall G, Grossman HA, Galpin JE, Blick G, Calabrese LH, Hirsch RL, Fisher A, Stampone P, et al.

J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Mar 1;8(3):279-88.PMID: 7859140 [PubMed - indexed for MEDLINE]Related articles

Zidovudine in asymptomatic human immunodeficiency virus infection. A controlled trial in persons with fewer than 500 CD4-positive cells per cubic millimeter. The AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases.

Volberding PA, Lagakos SW, Koch MA, Pettinelli C, Myers MW, Booth DK, Balfour HH Jr, Reichman RC, Bartlett JA, Hirsch MS, et al.

N Engl J Med. 1990 Apr 5;322(14):941-9.PMID: 1969115 [PubMed - indexed for MEDLINE]Related articles

Zidovudine in persons with asymptomatic HIV infection and CD4+ cell counts greater than 400 per cubic millimeter. The European-Australian Collaborative Group.

Cooper DA, Gatell JM, Kroon S, Clumeck N, Millard J, Goebel FD, Bruun JN, Stingl G, Melville RL, González-Lahoz J, et al.

N Engl J Med. 1993 Jul 29;329(5):297-303.PMID: 8100611 [PubMed - indexed for MEDLINE]Related articlesFree article

The efficacy and safety of zidovudine alone or as cotherapy with acyclovir for the treatment of patients with AIDS and AIDS-related complex: a double-blind randomized trial. European-Australian Collaborative Group.

Cooper DA, Pehrson PO, Pedersen C, Moroni M, Oksenhendler E, Rozenbaum W, Clumeck N, Faber V, Stille W, Hirschel B, et al.

AIDS. 1993 Feb;7(2):197-207.PMID: 8096703 [PubMed - indexed for MEDLINE]Related articles

Nevirapine, zidovudine, and didanosine compared with zidovudine and didanosine in patients with HIV-1 infection. A randomized, double-blind, placebo-controlled trial. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group Protocol 241 Investigators.

D'Aquila RT, Hughes MD, Johnson VA, Fischl MA, Sommadossi JP, Liou SH, Timpone J, Myers M, Basgoz N, Niu M, Hirsch MS.

Ann Intern Med. 1996 Jun 15;124(12):1019-30.PMID: 8633815 [PubMed - indexed for MEDLINE]Related articlesFree article

Combination and monotherapy with zidovudine and zalcitabine in patients with advanced HIV disease. The NIAID AIDS Clinical Trials Group.

Fischl MA, Stanley K, Collier AC, Arduino JM, Stein DS, Feinberg JE, Allan JD, Goldsmith JC, Powderly WG.

Ann Intern Med. 1995 Jan 1;122(1):24-32.PMID: 7985892 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical efficacy of monotherapy with stavudine compared with zidovudine in HIV-infected, zidovudine-experienced patients. A randomized, double-blind, controlled trial. Bristol-Myers Squibb Stavudine/019 Study Group.

Spruance SL, Pavia AT, Mellors JW, Murphy R, Gathe J Jr, Stool E, Jemsek JG, Dellamonica P, Cross A, Dunkle L.

Ann Intern Med. 1997 Mar 1;126(5):355-63.PMID: 9054279 [PubMed - indexed for MEDLINE]Related articlesFree article

The duration of zidovudine benefit in persons with asymptomatic HIV infection. Prolonged evaluation of protocol 019 of the AIDS Clinical Trials Group.

Volberding PA, Lagakos SW, Grimes JM, Stein DS, Balfour HH Jr, Reichman RC, Bartlett JA, Hirsch MS, Phair JP, Mitsuyasu RT, et al.

JAMA. 1994 Aug 10;272(6):437-42.PMID: 7913730 [PubMed - indexed for MEDLINE]Related articles

Didanosine compared with continued zidovudine therapy for HIV-infected patients with 200 to 500 CD4 cells/mm3. A double-blind, randomized, controlled trial. Canadian HIV Trials Network Protocol 002 Study Group.

Montaner JS, Schechter MT, Rachlis A, Gill J, Beaulieu R, Tsoukas C, Raboud J, Cameron B, Salomon H, Dunkle L, Smaldone L, Wainberg MA.

Ann Intern Med. 1995 Oct 15;123(8):561-71.PMID: 7677296 [PubMed - indexed for MEDLINE]Related articlesFree article

Interferon-alpha in patients with asymptomatic human immunodeficiency virus (HIV) infection. A randomized, placebo-controlled trial.

Lane HC, Davey V, Kovacs JA, Feinberg J, Metcalf JA, Herpin B, Walker R, Deyton L, Davey RT Jr, Falloon J, et al.

Ann Intern Med. 1990 Jun 1;112(11):805-11.PMID: 1971503 [PubMed - indexed for MEDLINE]Related articles

Zidovudine monotherapy versus zidovudine plus zalcitabine combination therapy in HIV-positive persons with CD4 cell counts 300-500 cells/mm3: a double-blind controlled trial. The M50003 Study Group Coordinating and Writing Committee.

Moyle GJ, Bouza E, Antunes F, Smith D, Harris R, Warburg M, Walker M.

Antivir Ther. 1997 Dec;2(4):229-36.PMID: 11327442 [PubMed - indexed for MEDLINE]Related articles

A controlled trial of intravenous immune globulin for the prevention of serious bacterial infections in children receiving zidovudine for advanced human immunodeficiency virus infection. Pediatric AIDS Clinical Trials Group.

Spector SA, Gelber RD, McGrath N, Wara D, Barzilai A, Abrams E, Bryson YJ, Dankner WM, Livingston RA, Connor EM.

N Engl J Med. 1994 Nov 3;331(18):1181-7.PMID: 7935655 [PubMed - indexed for MEDLINE]Related articlesFree article

A randomized controlled trial of a reduced daily dose of zidovudine in patients with the acquired immunodeficiency syndrome. The AIDS Clinical Trials Group.

Fischl MA, Parker CB, Pettinelli C, Wulfsohn M, Hirsch MS, Collier AC, Antoniskis D, Ho M, Richman DD, Fuchs E, et al.

N Engl J Med. 1990 Oct 11;323(15):1009-14.PMID: 1977079 [PubMed - indexed for MEDLINE]Related articles

CD4+ lymphocytes are an incomplete surrogate marker for clinical progression in persons with asymptomatic HIV infection taking zidovudine.

Choi S, Lagakos SW, Schooley RT, Volberding PA.

Ann Intern Med. 1993 May 1;118(9):674-80.PMID: 8096373 [PubMed - indexed for MEDLINE]Related articlesFree article

Concorde: MRC/ANRS randomised double-blind controlled trial of immediate and deferred zidovudine in symptom-free HIV infection. Concorde Coordinating Committee.

[No authors listed]

Lancet. 1994 Apr 9;343(8902):871-81.PMID: 7908356 [PubMed - indexed for MEDLINE]Related articles

Randomized double-blind, placebo-controlled trial of twice-daily zidovudine in asymptomatic haemophiliacs infected with the human immunodeficiency virus type 1. European-Australian Haemophilia Collaborative Study Group.

Mannucci PM, Gringeri A, Savidge G, Gatenby P, Laurian Y, Pabinger-Fasching I, Martinez-Vazquez JM, Hessey EW, Steel HM.

Br J Haematol. 1994 Jan;86(1):174-9.PMID: 7912097 [PubMed - indexed for MEDLINE]Related articles

Toxic effects of zidovudine in asymptomatic human immunodeficiency virus-infected individuals with CD4+ cell counts of 0.50 x 10(9)/L or less. Detailed and updated results from protocol 019 of the AIDS Clinical Trials Group.

Koch MA, Volberding PA, Lagakos SW, Booth DK, Pettinelli C, Myers MW.

Arch Intern Med. 1992 Nov;152(11):2286-92.PMID: 1359846 [PubMed - indexed for MEDLINE]Related articles

Combination therapy with zidovudine and dideoxycytidine in patients with advanced human immunodeficiency virus infection. A phase I/II study.

Meng TC, Fischl MA, Boota AM, Spector SA, Bennett D, Bassiakos Y, Lai SH, Wright B, Richman DD.

Ann Intern Med. 1992 Jan 1;116(1):13-20.PMID: 1345755 [PubMed - indexed for MEDLINE]Related articles