PubMed

Romidepsin inhibits Ras-dependent growth transformation of NIH 3T3 fibroblasts and RIE-1 epithelial cells independently of Ras signaling inhibition.

Hanker AB, Healy KD, Nichols J, Der CJ.

J Mol Signal. 2009 Aug 16;4:5.PMID: 19682393 [PubMed - in process]Free PMC ArticleFree textRelated citations

Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells.

Pruitt K, Ulkü AS, Frantz K, Rojas RJ, Muniz-Medina VM, Rangnekar VM, Der CJ, Shields JM.

J Biol Chem. 2005 Jun 17;280(24):23363-70. Epub 2005 Apr 14.PMID: 15831492 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase.

McFall A, Ulkü A, Lambert QT, Kusa A, Rogers-Graham K, Der CJ.

Mol Cell Biol. 2001 Aug;21(16):5488-99.PMID: 11463831 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Pharmacological inhibition of Ras-transformed epithelial cell growth is linked to down-regulation of epidermal growth factor-related peptides.

Sizemore N, Cox AD, Barnard JA, Oldham SM, Reynolds ER, Der CJ, Coffey RJ.

Gastroenterology. 1999 Sep;117(3):567-76.PMID: 10464132 [PubMed - indexed for MEDLINE]Related citations

Transformation by oncogenic Ras expands the early genomic response to transforming growth factor beta in intestinal epithelial cells.

Allen CE, Du J, Jiang B, Huang Q, Yakovich AJ, Barnard JA.

Neoplasia. 2008 Oct;10(10):1073-82.PMID: 18813357 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Involvement of fibroblast growth factor receptor 2 isoform switching in mammary oncogenesis.

Cha JY, Lambert QT, Reuther GW, Der CJ.

Mol Cancer Res. 2008 Mar;6(3):435-45.PMID: 18337450 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

The farnesyltransferase inhibitor, LB42708, inhibits growth and induces apoptosis irreversibly in H-ras and K-ras-transformed rat intestinal epithelial cells.

Kim HS, Kim JW, Gang J, Wen J, Koh SS, Koh JS, Chung HH, Song SY.

Toxicol Appl Pharmacol. 2006 Sep 15;215(3):317-29. Epub 2006 May 19.PMID: 16712893 [PubMed - indexed for MEDLINE]Related citations

A cross-talk between oncogenic Ras and tumor suppressor PTEN through FAK Tyr861 phosphorylation in NIH/3T3 mouse embryonic fibroblasts.

Bahk YY, Cho IH, Kim TS.

Biochem Biophys Res Commun. 2008 Dec 26;377(4):1199-204. Epub 2008 Nov 8.PMID: 19000654 [PubMed - indexed for MEDLINE]Related citations

Up-regulation of ras-GAP genes is reversed by a MEK inhibitor and doxorubicin in v-Ki-ras-transformed NIH/3T3 fibroblasts.

Hashii M, Fukuda M, Nomura H, Ito N, Takahashi H, Hattori S, Mikoshiba K, Noda M, Higuchi Y.

Biochem Biophys Res Commun. 2007 May 4;356(2):374-80. Epub 2007 Mar 5.PMID: 17367762 [PubMed - indexed for MEDLINE]Related citations

Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylase.

Kwon HJ, Owa T, Hassig CA, Shimada J, Schreiber SL.

Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3356-61.PMID: 9520369 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Glutamine deprivation induces abortive s-phase rescued by deoxyribonucleotides in k-ras transformed fibroblasts.

Gaglio D, Soldati C, Vanoni M, Alberghina L, Chiaradonna F.

PLoS One. 2009;4(3):e4715. Epub 2009 Mar 5.PMID: 19262748 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Ras-driven transformation of human nestin-positive pancreatic epithelial cells.

Campbell PM, Lee KM, Ouellette MM, Kim HJ, Groehler AL, Khazak V, Der CJ.

Methods Enzymol. 2008;439:451-65.PMID: 18374182 [PubMed - indexed for MEDLINE]Related citations

Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS(Q61L).

Yang D, Wang MT, Tang Y, Chen Y, Jiang H, Jones TT, Rao K, Brewer GJ, Singh KK, Nie D.

Cancer Biol Ther. 2010 Jan;9(2):122-33. Epub 2010 Jan 21.PMID: 19923925 [PubMed - in process]Free PMC ArticleFree textRelated citations

H-ras transformation sensitizes volume-activated anion channels and increases migratory activity of NIH3T3 fibroblasts.

Schneider L, Klausen TK, Stock C, Mally S, Christensen ST, Pedersen SF, Hoffmann EK, Schwab A.

Pflugers Arch. 2008 Mar;455(6):1055-62. Epub 2007 Oct 20.PMID: 17952454 [PubMed - indexed for MEDLINE]Related citations

Selective inhibition of ras-transformed cell growth by a novel fatty acid-based chloromethyl ketone designed to target Ras endoprotease.

Chen Y.

Ann N Y Acad Sci. 1999;886:103-8. Review.PMID: 10667208 [PubMed - indexed for MEDLINE]Related citations

Acquired glucose sensitivity of k-ras transformed fibroblasts.

Chiaradonna F, Magnani C, Sacco E, Manzoni R, Alberghina L, Vanoni M.

Biochem Soc Trans. 2005 Feb;33(Pt 1):297-9. Review.PMID: 15667331 [PubMed - indexed for MEDLINE]Related citations

Oleanolic acid isolated from Oldenlandia diffusa exhibits a unique growth inhibitory effect against ras-transformed fibroblasts.

Wu PK, Chi Shing Tai W, Liang ZT, Zhao ZZ, Hsiao WL.

Life Sci. 2009 Jul 17;85(3-4):113-21. Epub 2009 May 9.PMID: 19433096 [PubMed - indexed for MEDLINE]Related citations

Oncogenic Ras, but not (V600E)B-RAF, protects from cholesterol depletion-induced apoptosis through the PI3K/AKT pathway in colorectal cancer cells.

Calleros L, Sánchez-Hernández I, Baquero P, Toro MJ, Chiloeches A.

Carcinogenesis. 2009 Oct;30(10):1670-7. Epub 2009 Aug 20.PMID: 19700418 [PubMed - indexed for MEDLINE]Related citations

Romidepsin reduces histone deacetylase activity, induces acetylation of histones, inhibits proliferation, and activates apoptosis in immortalized epithelial endometriotic cells.

Imesch P, Fink D, Fedier A.

Fertil Steril. 2010 Jun 2. [Epub ahead of print]PMID: 20605144 [PubMed - as supplied by publisher]Related citations

Phosphorylation of histone H3 at Ser10: its role in cell transformation by v-Src.

Tange S, Ito S, Senga T, Hamaguchi M.

Biochem Biophys Res Commun. 2009 Sep 4;386(4):588-92. Epub 2009 Jun 18.PMID: 19540193 [PubMed - indexed for MEDLINE]Related citations