PubMed

The human immunodeficiency virus type 1 Vpr protein and its carboxy-terminally truncated form induce apoptosis in tumor cells.

Nonaka M, Hashimoto Y, Takeshima SN, Aida Y.

Cancer Cell Int. 2009 Aug 12;9:20.PMID: 19674438 [PubMed]Related articlesFree article

A carboxy-terminally truncated form of the human immunodeficiency virus type 1 Vpr protein induces apoptosis via G(1) cell cycle arrest.

Nishizawa M, Kamata M, Katsumata R, Aida Y.

J Virol. 2000 Jul;74(13):6058-67.PMID: 10846089 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of apoptosis by the Vpr protein of human immunodeficiency virus type 1 occurs independently of G(2) arrest of the cell cycle.

Nishizawa M, Kamata M, Mojin T, Nakai Y, Aida Y.

Virology. 2000 Oct 10;276(1):16-26.PMID: 11021990 [PubMed - indexed for MEDLINE]Related articles

A carboxy-terminally truncated form of the Vpr protein of human immunodeficiency virus type 1 retards cell proliferation independently of G(2) arrest of the cell cycle.

Nishizawa M, Myojin T, Nishino Y, Nakai Y, Kamata M, Aida Y.

Virology. 1999 Oct 25;263(2):313-22.PMID: 10544105 [PubMed - indexed for MEDLINE]Related articles

Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrest.

Stewart SA, Poon B, Jowett JB, Chen IS.

J Virol. 1997 Jul;71(7):5579-92.PMID: 9188632 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of cell cycle arrest, transactivation, and apoptosis induced by the simian immunodeficiency virus SIVagm and human immunodeficiency virus type 1 vpr genes.

Zhu Y, Gelbard HA, Roshal M, Pursell S, Jamieson BD, Planelles V.

J Virol. 2001 Apr;75(8):3791-801.PMID: 11264368 [PubMed - indexed for MEDLINE]Related articlesFree article

DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest.

Tan L, Ehrlich E, Yu XF.

J Virol. 2007 Oct;81(19):10822-30. Epub 2007 Jul 11.PMID: 17626091 [PubMed - indexed for MEDLINE]Related articlesFree article

Human immunodeficiency virus type 1 Vpr induces cell cycle arrest at the G(1) phase and apoptosis via disruption of mitochondrial function in rodent cells.

Azuma A, Matsuo A, Suzuki T, Kurosawa T, Zhang X, Aida Y.

Microbes Infect. 2006 Mar;8(3):670-9. Epub 2006 Jan 11.PMID: 16480911 [PubMed - indexed for MEDLINE]Related articles

HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase.

Belzile JP, Duisit G, Rougeau N, Mercier J, Finzi A, Cohen EA.

PLoS Pathog. 2007 Jul;3(7):e85.PMID: 17630831 [PubMed - indexed for MEDLINE]Related articlesFree article

Lentiviral delivery of HIV-1 Vpr protein induces apoptosis in transformed cells.

Stewart SA, Poon B, Jowett JB, Xie Y, Chen IS.

Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):12039-43.PMID: 10518572 [PubMed - indexed for MEDLINE]Related articlesFree article

Heat shock protein 70 protects cells from cell cycle arrest and apoptosis induced by human immunodeficiency virus type 1 viral protein R.

Iordanskiy S, Zhao Y, Dubrovsky L, Iordanskaya T, Chen M, Liang D, Bukrinsky M.

J Virol. 2004 Sep;78(18):9697-704.PMID: 15331702 [PubMed - indexed for MEDLINE]Related articlesFree article

The HIV-1 Vif protein mediates degradation of Vpr and reduces Vpr-induced cell cycle arrest.

Wang J, Shackelford JM, Selliah N, Shivers DK, O'Neill E, Garcia JV, Muthumani K, Weiner D, Yu XF, Gabuzda D, Finkel TH.

DNA Cell Biol. 2008 May;27(5):267-77.PMID: 18462066 [PubMed - indexed for MEDLINE]Related articles

Human immunodeficiency virus type 1 vpr gene induces phenotypic effects similar to those of the DNA alkylating agent, nitrogen mustard.

Poon B, Jowett JB, Stewart SA, Armstrong RW, Rishton GM, Chen IS.

J Virol. 1997 May;71(5):3961-71.PMID: 9094673 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of M-phase arrest and apoptosis after HIV-1 Vpr expression through uncoupling of nuclear and centrosomal cycle in HeLa cells.

Watanabe N, Yamaguchi T, Akimoto Y, Rattner JB, Hirano H, Nakauchi H.

Exp Cell Res. 2000 Aug 1;258(2):261-9.PMID: 10896777 [PubMed - indexed for MEDLINE]Related articles

HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT.

Andersen JL, DeHart JL, Zimmerman ES, Ardon O, Kim B, Jacquot G, Benichou S, Planelles V.

PLoS Pathog. 2006 Dec;2(12):e127.PMID: 17140287 [PubMed - indexed for MEDLINE]Related articlesFree article

[Cell cycle G2 arrest, cell death and nuclear localization induced by human immunodeficiency virus type 1 protein R (VPR) in cervical cancer cells]

Yang J, Yi Y, Wang J.

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2000 Sep;14(3):223-6, 301.PMID: 11498683 [PubMed - indexed for MEDLINE]Related articles

Human immunodeficiency virus type 1 Vpr modifies cell proliferation via multiple pathways.

Yamaguchi T, Watanabe N, Nakauchi H, Koito A.

Microbiol Immunol. 1999;43(5):437-47.PMID: 10449250 [PubMed - indexed for MEDLINE]Related articles

Specific G2 arrest of caprine cells infected with a caprine arthritis encephalitis virus expressing vpr and vpx genes from simian immunodeficiency virus.

Bouzar AB, Guiguen F, Morin T, Villet S, Fornazero C, Garnier C, Gallay K, Gounel F, Favier C, Durand J, Balleydier S, Mornex JF, Narayan O, Chebloune Y.

Virology. 2003 Apr 25;309(1):41-52.PMID: 12726725 [PubMed - indexed for MEDLINE]Related articles

Nuclear localization of Vpr is crucial for the efficient replication of HIV-1 in primary CD4+ T cells.

Iijima S, Nitahara-Kasahara Y, Kimata K, Zhong Zhuang W, Kamata M, Isogai M, Miwa M, Tsunetsugu-Yokota Y, Aida Y.

Virology. 2004 Oct 1;327(2):249-61.PMID: 15351213 [PubMed - indexed for MEDLINE]Related articles

Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle.

Hrecka K, Gierszewska M, Srivastava S, Kozaczkiewicz L, Swanson SK, Florens L, Washburn MP, Skowronski J.

Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11778-83. Epub 2007 Jul 3.PMID: 17609381 [PubMed - indexed for MEDLINE]Related articlesFree article