PubMed

An integration of complementary strategies for gene-expression analysis to reveal novel therapeutic opportunities for breast cancer.

Bild AH, Parker JS, Gustafson AM, Acharya CR, Hoadley KA, Anders C, Marcom PK, Carey LA, Potti A, Nevins JR, Perou CM.

Breast Cancer Res. 2009;11(4):R55. Epub 2009 Jul 28.PMID: 19638211 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer.

Acharya CR, Hsu DS, Anders CK, Anguiano A, Salter KH, Walters KS, Redman RC, Tuchman SA, Moylan CA, Mukherjee S, Barry WT, Dressman HK, Ginsburg GS, Marcom KP, Garman KS, Lyman GH, Nevins JR, Potti A.

JAMA. 2008 Apr 2;299(13):1574-87.PMID: 18387932 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression profiles of tumor biology provide a novel approach to prognosis and may guide the selection of therapeutic targets in multiple myeloma.

Anguiano A, Tuchman SA, Acharya C, Salter K, Gasparetto C, Zhan F, Dhodapkar M, Nevins J, Barlogie B, Shaughnessy JD Jr, Potti A.

J Clin Oncol. 2009 Sep 1;27(25):4197-203. Epub 2009 Jul 27.PMID: 19636021 [PubMed - indexed for MEDLINE]Related articles

Oncogenic pathway signatures in human cancers as a guide to targeted therapies.

Bild AH, Yao G, Chang JT, Wang Q, Potti A, Chasse D, Joshi MB, Harpole D, Lancaster JM, Berchuck A, Olson JA Jr, Marks JR, Dressman HK, West M, Nevins JR.

Nature. 2006 Jan 19;439(7074):353-7. Epub 2005 Nov 6.PMID: 16273092 [PubMed - indexed for MEDLINE]Related articles

Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms.

Sørlie T, Wang Y, Xiao C, Johnsen H, Naume B, Samaha RR, Børresen-Dale AL.

BMC Genomics. 2006 May 26;7:127.PMID: 16729877 [PubMed - indexed for MEDLINE]Related articlesFree article

Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation.

Smith DD, Saetrom P, Snøve O Jr, Lundberg C, Rivas GE, Glackin C, Larson GP.

BMC Bioinformatics. 2008 Jan 28;9:63.PMID: 18226260 [PubMed - indexed for MEDLINE]Related articlesFree article

Oncogene protein co-expression. Value of Ha-ras, c-myc, c-fos, and p53 as prognostic discriminants for breast carcinoma.

Bland KI, Konstadoulakis MM, Vezeridis MP, Wanebo HJ.

Ann Surg. 1995 Jun;221(6):706-18; discussion 718-20.PMID: 7794075 [PubMed - indexed for MEDLINE]Related articlesFree article

Elucidating the altered transcriptional programs in breast cancer using independent component analysis.

Teschendorff AE, Journée M, Absil PA, Sepulchre R, Caldas C.

PLoS Comput Biol. 2007 Aug;3(8):e161. Epub 2007 Jun 29.PMID: 17708679 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional genomic analysis of drug sensitivity pathways to guide adjuvant strategies in breast cancer.

Swanton C, Szallasi Z, Brenton JD, Downward J.

Breast Cancer Res. 2008;10(5):214. Epub 2008 Oct 31. Review.PMID: 18986507 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression patterns associated with p53 status in breast cancer.

Troester MA, Herschkowitz JI, Oh DS, He X, Hoadley KA, Barbier CS, Perou CM.

BMC Cancer. 2006 Dec 6;6:276.PMID: 17150101 [PubMed - indexed for MEDLINE]Related articlesFree article

A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.

Berns K, Horlings HM, Hennessy BT, Madiredjo M, Hijmans EM, Beelen K, Linn SC, Gonzalez-Angulo AM, Stemke-Hale K, Hauptmann M, Beijersbergen RL, Mills GB, van de Vijver MJ, Bernards R.

Cancer Cell. 2007 Oct;12(4):395-402.PMID: 17936563 [PubMed - indexed for MEDLINE]Related articles

Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer.

Bergamaschi A, Kim YH, Wang P, Sørlie T, Hernandez-Boussard T, Lonning PE, Tibshirani R, Børresen-Dale AL, Pollack JR.

Genes Chromosomes Cancer. 2006 Nov;45(11):1033-40.PMID: 16897746 [PubMed - indexed for MEDLINE]Related articles

Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery.

Kao J, Salari K, Bocanegra M, Choi YL, Girard L, Gandhi J, Kwei KA, Hernandez-Boussard T, Wang P, Gazdar AF, Minna JD, Pollack JR.

PLoS One. 2009 Jul 3;4(7):e6146.PMID: 19582160 [PubMed - indexed for MEDLINE]Related articlesFree article

Overview of resistance to systemic therapy in patients with breast cancer.

Gonzalez-Angulo AM, Morales-Vasquez F, Hortobagyi GN.

Adv Exp Med Biol. 2007;608:1-22. Review.PMID: 17993229 [PubMed - indexed for MEDLINE]Related articles

An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer.

Dressman HK, Berchuck A, Chan G, Zhai J, Bild A, Sayer R, Cragun J, Clarke J, Whitaker RS, Li L, Gray J, Marks J, Ginsburg GS, Potti A, West M, Nevins JR, Lancaster JM.

J Clin Oncol. 2007 Feb 10;25(5):517-25.PMID: 17290060 [PubMed - indexed for MEDLINE]Related articles

An integrative approach to characterize disease-specific pathways and their coordination: a case study in cancer.

Xu M, Kao MC, Nunez-Iglesias J, Nevins JR, West M, Zhou XJ.

BMC Genomics. 2008;9 Suppl 1:S12.PMID: 18366601 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potential.

Andrechek ER, Cardiff RD, Chang JT, Gatza ML, Acharya CR, Potti A, Nevins JR.

Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16387-92. Epub 2009 Sep 4.PMID: 19805309 [PubMed - indexed for MEDLINE]Related articles

Gene expression signatures in breast cancer distinguish phenotype characteristics, histologic subtypes, and tumor invasiveness.

Pedraza V, Gomez-Capilla JA, Escaramis G, Gomez C, Torné P, Rivera JM, Gil A, Araque P, Olea N, Estivill X, Fárez-Vidal ME.

Cancer. 2010 Jan 15;116(2):486-96.PMID: 20029976 [PubMed - indexed for MEDLINE]Related articles

Revealing targeted therapy for human cancer by gene module maps.

Wong DJ, Nuyten DS, Regev A, Lin M, Adler AS, Segal E, van de Vijver MJ, Chang HY.

Cancer Res. 2008 Jan 15;68(2):369-78.PMID: 18199530 [PubMed - indexed for MEDLINE]Related articlesFree article

An integrated approach to the prediction of chemotherapeutic response in patients with breast cancer.

Salter KH, Acharya CR, Walters KS, Redman R, Anguiano A, Garman KS, Anders CK, Mukherjee S, Dressman HK, Barry WT, Marcom KP, Olson J, Nevins JR, Potti A.

PLoS One. 2008 Apr 2;3(4):e1908.PMID: 18382681 [PubMed - indexed for MEDLINE]Related articlesFree article