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Results: 1 to 20 of 107

1.

Structural and functional implications of p53 missense cancer mutations.

Tan Y, Luo R.

PMC Biophys. 2009 Jun 26;2(1):5.PMID: 19558684 [PubMed - in process]Related articlesFree article

2.

Stabilization of proteins by enhancement of inter-residue hydrophobic contacts: lessons of T4 lysozyme and barnase.

Golovanov AP, Vergoten G, Arseniev AS.

J Biomol Struct Dyn. 2000 Dec;18(3):477-91.PMID: 11149522 [PubMed - indexed for MEDLINE]Related articles

3.

Comparison of the human and worm p53 structures suggests a way for enhancing stability.

Pan Y, Ma B, Levine AJ, Nussinov R.

Biochemistry. 2006 Mar 28;45(12):3925-33.PMID: 16548519 [PubMed - indexed for MEDLINE]Related articles

4.

Molecular dynamics simulations of p53 DNA-binding domain.

Lu Q, Tan YH, Luo R.

J Phys Chem B. 2007 Oct 4;111(39):11538-45. Epub 2007 Sep 8.PMID: 17824689 [PubMed - indexed for MEDLINE]Related articlesFree article

5.

Disease-associated substitutions in the filamin B actin binding domain confer enhanced actin binding affinity in the absence of major structural disturbance: Insights from the crystal structures of filamin B actin binding domains.

Sawyer GM, Clark AR, Robertson SP, Sutherland-Smith AJ.

J Mol Biol. 2009 Jul 31;390(5):1030-47. Epub 2009 Jun 6.PMID: 19505475 [PubMed - indexed for MEDLINE]Related articles

6.

Predicting the transactivation activity of p53 missense mutants using a four-body potential score derived from Delaunay tessellations.

Mathe E, Olivier M, Kato S, Ishioka C, Vaisman I, Hainaut P.

Hum Mutat. 2006 Feb;27(2):163-72.PMID: 16395672 [PubMed - indexed for MEDLINE]Related articles

7.

Stabilising the DNA-binding domain of p53 by rational design of its hydrophobic core.

Khoo KH, Joerger AC, Freund SM, Fersht AR.

Protein Eng Des Sel. 2009 Jul;22(7):421-30. Epub 2009 Jun 10.PMID: 19515728 [PubMed - indexed for MEDLINE]Related articlesFree article

8.

[Advances on mutant p53 research]

Li DH, Zhang LQ, He FC.

Yi Chuan. 2008 Jun;30(6):697-703. Review. Chinese. PMID: 18550490 [PubMed - indexed for MEDLINE]Related articles

9.

Alport syndrome. Molecular genetic aspects.

Hertz JM.

Dan Med Bull. 2009 Aug;56(3):105-52.PMID: 19728970 [PubMed - indexed for MEDLINE]Related articles

10.

Pathogenic mechanisms of tooth agenesis linked to paired domain mutations in human PAX9.

Wang Y, Groppe JC, Wu J, Ogawa T, Mues G, D'Souza RN, Kapadia H.

Hum Mol Genet. 2009 Aug 1;18(15):2863-74. Epub 2009 May 9.PMID: 19429910 [PubMed - indexed for MEDLINE]Related articles

11.

Inactive full-length p53 mutants lacking dominant wild-type p53 inhibition highlight loss of heterozygosity as an important aspect of p53 status in human cancers.

Dearth LR, Qian H, Wang T, Baroni TE, Zeng J, Chen SW, Yi SY, Brachmann RK.

Carcinogenesis. 2007 Feb;28(2):289-98. Epub 2006 Jul 21.PMID: 16861262 [PubMed - indexed for MEDLINE]Related articlesFree article

12.

cDNA sequencing improves the detection of P53 missense mutations in colorectal cancer.

Szybka M, Zakrzewska M, Rieske P, Pasz-Walczak G, Kulczycka-Wojdala D, Zawlik I, Stawski R, Jesionek-Kupnicka D, Liberski PP, Kordek R.

BMC Cancer. 2009 Aug 11;9:278.PMID: 19671129 [PubMed - indexed for MEDLINE]Related articlesFree article

13.

Pathogenic or not? And if so, then how? Studying the effects of missense mutations using bioinformatics methods.

Thusberg J, Vihinen M.

Hum Mutat. 2009 May;30(5):703-14. Review.PMID: 19267389 [PubMed - indexed for MEDLINE]Related articles

14.

Li-Fraumeni and Li-Fraumeni-like syndrome mutations in p53 are associated with exonic methylation and splicing regulatory elements.

Kouidou S, Malousi A, Maglaveras N.

Mol Carcinog. 2009 Oct;48(10):895-902.PMID: 19367569 [PubMed - indexed for MEDLINE]Related articles

15.

How protein stability and new functions trade off.

Tokuriki N, Stricher F, Serrano L, Tawfik DS.

PLoS Comput Biol. 2008 Feb 29;4(2):e1000002.PMID: 18463696 [PubMed - indexed for MEDLINE]Related articlesFree article

16.

Mutant p53 mediates survival of breast cancer cells.

Lim LY, Vidnovic N, Ellisen LW, Leong CO.

Br J Cancer. 2009 Nov 3;101(9):1606-12. Epub 2009 Sep 22.PMID: 19773755 [PubMed - indexed for MEDLINE]Related articles

17.

Comparison of computational approaches for predicting the effects of missense mutations on p53 function.

Chong LT, Pitera JW, Swope WC, Pande VS.

J Mol Graph Model. 2009 Jun-Jul;27(8):978-82. Epub 2008 Dec 27.PMID: 19168381 [PubMed - indexed for MEDLINE]Related articles

18.

Structural analysis of eight novel and 112 previously reported missense mutations in the interactive FXI mutation database reveals new insight on FXI deficiency.

Saunders RE, Shiltagh N, Gomez K, Mellars G, Cooper C, Perry DJ, Tuddenham EG, Perkins SJ.

Thromb Haemost. 2009 Aug;102(2):287-301.PMID: 19652879 [PubMed - indexed for MEDLINE]Related articles

19.

Characterization of a new cancer-associated mutant of p53 with a missense mutation (K351N) in the tetramerization domain.

Muscolini M, Montagni E, Caristi S, Nomura T, Kamada R, Di Agostino S, Corazzari M, Piacentini M, Blandino G, Costanzo A, Sakaguchi K, Tuosto L.

Cell Cycle. 2009 Oct 15;8(20):3396-405. Epub 2009 Oct 24.PMID: 19806023 [PubMed - indexed for MEDLINE]Related articles

20.

The SV40 capsid is stabilized by a conserved pentapeptide hinge of the major capsid protein VP1.

Ben-nun-Shaul O, Bronfeld H, Reshef D, Schueler-Furman O, Oppenheim A.

J Mol Biol. 2009 Mar 13;386(5):1382-91. Epub 2008 Nov 27.PMID: 19094992 [PubMed - indexed for MEDLINE]Related articlesFree article

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