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Antimicrobial breakpoint estimation accounting for variability in pharmacokinetics.

Bi GD, Li J, Nekka F.

Theor Biol Med Model. 2009 Jun 26;6:10.PMID: 19558679 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Pharmacodynamics: relation to antimicrobial resistance.

Rybak MJ.

Am J Infect Control. 2006 Jun;34(5 Suppl 1):S38-45; discussion S64-73. Review.PMID: 16813981 [PubMed - indexed for MEDLINE]Related citations

New concept and a theoretical consideration of the mechanism-based pharmacokinetics/ pharmacodynamics (PK/PD) modeling for antimicrobial agents.

Sato N, Suzuki H, Hayashi H, Shibasaki S, Sugano T, Maebashi K, Kurosawa T, Shiomi M, Ogata H.

Jpn J Antibiot. 2008 Oct;61(5):314-38.PMID: 19260351 [PubMed - indexed for MEDLINE]Related citations

The integrated use of pharmacokinetic and pharmacodynamic models for the definition of breakpoints.

Stass H, Dalhoff A.

Infection. 2005 Dec;33 Suppl 2:29-35.PMID: 16518709 [PubMed - indexed for MEDLINE]Related citations

Rational dosing of antimicrobial agents: pharmacokinetic and pharmacodynamic strategies.

Owens RC Jr, Shorr AF.

Am J Health Syst Pharm. 2009 Jun 15;66(12 Suppl 4):S23-30.PMID: 19502225 [PubMed - indexed for MEDLINE]Related citations

Optimisation of antimicrobial therapy using pharmacokinetic and pharmacodynamic parameters.

Jacobs MR.

Clin Microbiol Infect. 2001 Nov;7(11):589-96. Review.PMID: 11737083 [PubMed - indexed for MEDLINE]Related citations

Pharmacodynamics: relation to antimicrobial resistance.

Rybak MJ.

Am J Med. 2006 Jun;119(6 Suppl 1):S37-44; discussion S62-70. Review.PMID: 16735150 [PubMed - indexed for MEDLINE]Related citations

The pharmacokinetic-pharmacodynamic approach to a rational dosage regimen for antibiotics.

Toutain PL, del Castillo JR, Bousquet-Mélou A.

Res Vet Sci. 2002 Oct;73(2):105-14. Review.PMID: 12204627 [PubMed - indexed for MEDLINE]Related citations

Tools to define the relevance of PK/PD parameters to the efficacy, toxicity and emergence of resistance of antimicrobials.

Hickey E.

Curr Opin Drug Discov Devel. 2007 Jan;10(1):49-52. Review.PMID: 17265741 [PubMed - indexed for MEDLINE]Related citations

Integration of pharmacokinetic and pharmacodynamic indices of marbofloxacin in turkeys.

Haritova AM, Rusenova NV, Parvanov PR, Lashev LD, Fink-Gremmels J.

Antimicrob Agents Chemother. 2006 Nov;50(11):3779-85. Epub 2006 Aug 28.PMID: 16940071 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Pharmacokinetic-pharmacodynamic modeling and simulation for in vivo bactericidal effect in murine infection model.

Katsube T, Yamano Y, Yano Y.

J Pharm Sci. 2008 Apr;97(4):1606-14.PMID: 17705288 [PubMed - indexed for MEDLINE]Related citations

A combined in vivo pharmacokinetic-in vitro pharmacodynamic approach to simulate target site pharmacodynamics of antibiotics in humans.

Delacher S, Derendorf H, Hollenstein U, Brunner M, Joukhadar C, Hofmann S, Georgopoulos A, Eichler HG, Müller M.

J Antimicrob Chemother. 2000 Nov;46(5):733-9.PMID: 11062192 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Pharmacokinetic/pharmacodynamic relationships of antimicrobial drugs used in veterinary medicine.

McKellar QA, Sanchez Bruni SF, Jones DG.

J Vet Pharmacol Ther. 2004 Dec;27(6):503-14. Review.PMID: 15601444 [PubMed - indexed for MEDLINE]Related citations

Effect of treatment duration on pharmacokinetic/pharmacodynamic indices correlating with therapeutic efficacy of ceftazidime in experimental Klebsiella pneumoniae lung infection.

Bakker-Woudenberg IA, ten Kate MT, Goessens WH, Mouton JW.

Antimicrob Agents Chemother. 2006 Sep;50(9):2919-25.PMID: 16940082 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

How predictive is PK/PD for antibacterial agents?

Frimodt-Møller N.

Int J Antimicrob Agents. 2002 Apr;19(4):333-9. Review.PMID: 11978504 [PubMed - indexed for MEDLINE]Related citations

Pharmacokinetics and pharmacodynamics of antimicrobial drugs.

Czock D, Markert C, Hartman B, Keller F.

Expert Opin Drug Metab Toxicol. 2009 May;5(5):475-87. Review.PMID: 19416084 [PubMed - indexed for MEDLINE]Related citations

Interindividual variability in plasma concentrations after systemic exposure of swine to dietary doxycycline supplied with and without paracetamol: a population pharmacokinetic approach.

del Castillo JR, Laroute V, Pommier P, Zémirline C, Keïta A, Concordet D, Toutain PL.

J Anim Sci. 2006 Nov;84(11):3155-66.PMID: 17032811 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Optimal antibiotic dosing. The pharmacokinetic-pharmacodynamic interface.

Reed MD.

Postgrad Med. 2000 Dec;108(7 Suppl Contemporaty):17-24. Review.PMID: 19667545 [PubMed - indexed for MEDLINE]Related citations

[Pharmacokinetic/pharmacodynamic analysis to optimize antibacterial treatments: prediction of efficacy by using Montecarlo simulation techniques]

Sánchez Navarro A.

Rev Esp Quimioter. 2005 Sep;18(3):230-5. Spanish. PMID: 16369666 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

[An example of simulation for a better understanding of PK/PD relationship of antibiotics]

Le Normand Y, Ganiere-Monteil C, Drugeon H, Abbas S, Mazeas M, Kergueris MF.

Pathol Biol (Paris). 2004 Dec;52(10):597-601. French. PMID: 15596309 [PubMed - indexed for MEDLINE]Related citations