PubMed

Characterization of the tumor marker muc16 (ca125) expressed by murine ovarian tumor cell lines and identification of a panel of cross-reactive monoclonal antibodies.

Goodell CA, Belisle JA, Gubbels JA, Migneault M, Rancourt C, Connor J, Kunnimalaiyaan M, Kravitz R, Tucker W, Zwick M, Patankar MS.

J Ovarian Res. 2009 Jun 18;2(1):8.PMID: 19538730 [PubMed - in process]Free PMC ArticleFree textRelated citations

Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors.

Gubbels JA, Belisle J, Onda M, Rancourt C, Migneault M, Ho M, Bera TK, Connor J, Sathyanarayana BK, Lee B, Pastan I, Patankar MS.

Mol Cancer. 2006 Oct 26;5(1):50.PMID: 17067392 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

MUC16 mucin is expressed by the human ocular surface epithelia and carries the H185 carbohydrate epitope.

Argüeso P, Spurr-Michaud S, Russo CL, Tisdale A, Gipson IK.

Invest Ophthalmol Vis Sci. 2003 Jun;44(6):2487-95.PMID: 12766047 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

MUC16 expression during embryogenesis, in adult tissues, and ovarian cancer in the mouse.

Wang Y, Cheon DJ, Lu Z, Cunningham SL, Chen CM, Luo RZ, Xing D, Orsulic S, Bast RC Jr, Behringer RR.

Differentiation. 2008 Dec;76(10):1081-92. Epub 2008 Jul 2.PMID: 18637025 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes.

Belisle JA, Horibata S, Jennifer GA, Petrie S, Kapur A, André S, Gabius HJ, Rancourt C, Connor J, Paulson JC, Patankar MS.

Mol Cancer. 2010 May 24;9:118.PMID: 20497550 [PubMed - in process]Free PMC ArticleFree textRelated citations

CA125 (MUC16) tumor antigen selectively modulates the sensitivity of ovarian cancer cells to genotoxic drug-induced apoptosis.

Boivin M, Lane D, Piché A, Rancourt C.

Gynecol Oncol. 2009 Dec;115(3):407-13. Epub 2009 Sep 10.PMID: 19747716 [PubMed - indexed for MEDLINE]Related citations

Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion.

Rump A, Morikawa Y, Tanaka M, Minami S, Umesaki N, Takeuchi M, Miyajima A.

J Biol Chem. 2004 Mar 5;279(10):9190-8. Epub 2003 Dec 15.PMID: 14676194 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

A binding domain on mesothelin for CA125/MUC16.

Kaneko O, Gong L, Zhang J, Hansen JK, Hassan R, Lee B, Ho M.

J Biol Chem. 2009 Feb 6;284(6):3739-49. Epub 2008 Dec 15.PMID: 19075018 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Molecular cloning of the CA125 ovarian cancer antigen: identification as a new mucin, MUC16.

Yin BW, Lloyd KO.

J Biol Chem. 2001 Jul 20;276(29):27371-5. Epub 2001 May 21.PMID: 11369781 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Novel Monoclonal Antibodies Against the Proximal (Carboxy-Terminal) Portions of MUC16.

Dharma Rao T, Park KJ, Smith-Jones P, Iasonos A, Linkov I, Soslow RA, Spriggs DR.

Appl Immunohistochem Mol Morphol. 2010 May 7. [Epub ahead of print]PMID: 20453816 [PubMed - as supplied by publisher]Related citations

Daunorubicin conjugated to a monoclonal anti-CA125 antibody selectively kills human ovarian cancer cells.

Sweet F, Rosik LO, Sommers GM, Collins JL.

Gynecol Oncol. 1989 Sep;34(3):305-11.PMID: 2788601 [PubMed - indexed for MEDLINE]Related citations

Armed antibodies targeting the mucin repeats of the ovarian cancer antigen, MUC16, are highly efficacious in animal tumor models.

Chen Y, Clark S, Wong T, Chen Y, Chen Y, Dennis MS, Luis E, Zhong F, Bheddah S, Koeppen H, Gogineni A, Ross S, Polakis P, Mallet W.

Cancer Res. 2007 May 15;67(10):4924-32. Erratum in: Cancer Res. 2007 Jun 15;67(12):5998. Ross, Sarajane [added]. PMID: 17510422 [PubMed - indexed for MEDLINE]Related citations

CA125/MUC16 is dispensable for mouse development and reproduction.

Cheon DJ, Wang Y, Deng JM, Lu Z, Xiao L, Chen CM, Bast RC, Behringer RR.

PLoS One. 2009;4(3):e4675. Epub 2009 Mar 5.PMID: 19262696 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Ovarian cancer antigen CA125 is encoded by the MUC16 mucin gene.

Yin BW, Dnistrian A, Lloyd KO.

Int J Cancer. 2002 Apr 10;98(5):737-40.PMID: 11920644 [PubMed - indexed for MEDLINE]Related citations

Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer.

Pulaski HL, Spahlinger G, Silva IA, McLean K, Kueck AS, Reynolds RK, Coukos G, Conejo-Garcia JR, Buckanovich RJ.

J Transl Med. 2009 Jun 19;7:49.PMID: 19545375 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Human monoclonal antibody for ovarian clear cell carcinoma-2, a human monoclonal antibody with antitumor activity against ovarian cancer cells that recognizes CA125-like antigen.

Suzuki N, Tamada Y, Shigirahara K, Suzuki A, Susumu N, Ishida I, Aoki D.

Int J Gynecol Cancer. 2008 Sep-Oct;18(5):996-1006. Epub 2007 Nov 20.PMID: 18028379 [PubMed - indexed for MEDLINE]Related citations

Successful eradication of established peritoneal ovarian tumors in SCID-Beige mice following adoptive transfer of T cells genetically targeted to the MUC16 antigen.

Chekmasova AA, Rao TD, Nikhamin Y, Park KJ, Levine DA, Spriggs DR, Brentjens RJ.

Clin Cancer Res. 2010 Jul 15;16(14):3594-606. Epub 2010 Jul 13.PMID: 20628030 [PubMed - in process]Related citations

CA125 expression in spontaneous ovarian adenocarcinomas from laying hens.

Jackson E, Anderson K, Ashwell C, Petitte J, Mozdziak PE.

Gynecol Oncol. 2007 Jan;104(1):192-8. Epub 2006 Aug 30.PMID: 16942793 [PubMed - indexed for MEDLINE]Related citations

MUC16 is produced in tracheal surface epithelium and submucosal glands and is present in secretions from normal human airway and cultured bronchial epithelial cells.

Davies JR, Kirkham S, Svitacheva N, Thornton DJ, Carlstedt I.

Int J Biochem Cell Biol. 2007;39(10):1943-54. Epub 2007 May 25.PMID: 17604678 [PubMed - indexed for MEDLINE]Related citations

Conversion of murine antibodies to human antibodies and their optimization for ovarian cancer therapy targeted to the folate receptor.

Figini M, Martin F, Ferri R, Luison E, Ripamonti E, Zacchetti A, Mortarino M, Di Cioccio V, Maurizi G, Allegretti M, Canevari S.

Cancer Immunol Immunother. 2009 Apr;58(4):531-46. Epub 2008 Aug 15.PMID: 18704410 [PubMed - indexed for MEDLINE]Related citations