PubMed

Activin signaling as an emerging target for therapeutic interventions.

Tsuchida K, Nakatani M, Hitachi K, Uezumi A, Sunada Y, Ageta H, Inokuchi K.

Cell Commun Signal. 2009 Jun 18;7:15.PMID: 19538713 [PubMed - in process]Related articlesFree article

Signal transduction pathway through activin receptors as a therapeutic target of musculoskeletal diseases and cancer.

Tsuchida K, Nakatani M, Uezumi A, Murakami T, Cui X.

Endocr J. 2008 Mar;55(1):11-21. Epub 2007 Sep 14. Review.PMID: 17878607 [PubMed - indexed for MEDLINE]Related articlesFree article

Activin signaling and its role in regulation of cell proliferation, apoptosis, and carcinogenesis.

Chen YG, Wang Q, Lin SL, Chang CD, Chuang J, Ying SY.

Exp Biol Med (Maywood). 2006 May;231(5):534-44. Review. Erratum in: Exp Biol Med (Maywood). 2006 Sep;231(8):1448. Chung, Jody [corrected to Chuang, Jody]. PMID: 16636301 [PubMed - indexed for MEDLINE]Related articlesFree article

Activins, myostatin and related TGF-beta family members as novel therapeutic targets for endocrine, metabolic and immune disorders.

Tsuchida K.

Curr Drug Targets Immune Endocr Metabol Disord. 2004 Jun;4(2):157-66. Review.PMID: 15180456 [PubMed - indexed for MEDLINE]Related articles

The Delta intracellular domain mediates TGF-beta/Activin signaling through binding to Smads and has an important bi-directional function in the Notch-Delta signaling pathway.

Hiratochi M, Nagase H, Kuramochi Y, Koh CS, Ohkawara T, Nakayama K.

Nucleic Acids Res. 2007;35(3):912-22. Epub 2007 Jan 23.PMID: 17251195 [PubMed - indexed for MEDLINE]Related articlesFree article

An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors.

Harrison CA, Gray PC, Fischer WH, Donaldson C, Choe S, Vale W.

J Biol Chem. 2004 Jul 2;279(27):28036-44. Epub 2004 Apr 27.PMID: 15123686 [PubMed - indexed for MEDLINE]Related articlesFree article

Activin-A, transforming growth factor-beta, and myostatin signaling pathway in experimental dilated cardiomyopathy.

Mahmoudabady M, Mathieu M, Dewachter L, Hadad I, Ray L, Jespers P, Brimioulle S, Naeije R, McEntee K.

J Card Fail. 2008 Oct;14(8):703-9. Epub 2008 Jun 11.PMID: 18926443 [PubMed - indexed for MEDLINE]Related articles

Cripto forms a complex with activin and type II activin receptors and can block activin signaling.

Gray PC, Harrison CA, Vale W.

Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5193-8. Epub 2003 Apr 7.PMID: 12682303 [PubMed - indexed for MEDLINE]Related articlesFree article

Activin receptor signaling.

Abe Y, Minegishi T, Leung PC.

Growth Factors. 2004 Jun;22(2):105-10. Review.PMID: 15253386 [PubMed - indexed for MEDLINE]Related articles

[Transforming growth factor-beta as a therapeutic target]

Gálvez-Gastélum FJ, Sandoval-Rodríguez AS, Armendáriz-Borunda J.

Salud Publica Mex. 2004 Jul-Aug;46(4):341-50. Review. Spanish. PMID: 15468575 [PubMed - indexed for MEDLINE]Related articles

Distinct signaling of Drosophila Activin/TGF-beta family members.

Gesualdi SC, Haerry TE.

Fly (Austin). 2007 Jul-Aug;1(4):212-21. Epub 2007 Jul 4.PMID: 18820452 [PubMed - indexed for MEDLINE]Related articles

Acetylation of Smad2 by the co-activator p300 regulates activin and transforming growth factor beta response.

Tu AW, Luo K.

J Biol Chem. 2007 Jul 20;282(29):21187-96. Epub 2007 May 3.PMID: 17478422 [PubMed - indexed for MEDLINE]Related articlesFree article

Down-regulation of activin, activin receptors, and Smads in high-grade breast cancer.

Jeruss JS, Sturgis CD, Rademaker AW, Woodruff TK.

Cancer Res. 2003 Jul 1;63(13):3783-90.PMID: 12839974 [PubMed - indexed for MEDLINE]Related articlesFree article

Antagonists of activin signaling: mechanisms and potential biological applications.

Harrison CA, Gray PC, Vale WW, Robertson DM.

Trends Endocrinol Metab. 2005 Mar;16(2):73-8. Review.PMID: 15734148 [PubMed - indexed for MEDLINE]Related articles

Activin A/bone morphogenetic protein (BMP) chimeras exhibit BMP-like activity and antagonize activin and myostatin.

Korupolu RV, Muenster U, Read JD, Vale W, Fischer WH.

J Biol Chem. 2008 Feb 15;283(7):3782-90. Epub 2007 Dec 3.PMID: 18056265 [PubMed - indexed for MEDLINE]Related articlesFree article

Activin and transforming growth factor-beta signaling pathways are activated after allergen challenge in mild asthma.

Kariyawasam HH, Pegorier S, Barkans J, Xanthou G, Aizen M, Ying S, Kay AB, Lloyd CM, Robinson DS.

J Allergy Clin Immunol. 2009 Sep;124(3):454-62.PMID: 19733294 [PubMed - indexed for MEDLINE]Related articles

Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators.

Balemans W, Van Hul W.

Dev Biol. 2002 Oct 15;250(2):231-50. Review.PMID: 12376100 [PubMed - indexed for MEDLINE]Related articles

The TGF-beta superfamily and its roles in the human ovary and placenta.

Peng C.

J Obstet Gynaecol Can. 2003 Oct;25(10):834-44. Review.PMID: 14532952 [PubMed - indexed for MEDLINE]Related articles

The activin signaling pathway promotes differentiation of dI3 interneurons in the spinal neural tube.

Timmer J, Chesnutt C, Niswander L.

Dev Biol. 2005 Sep 1;285(1):1-10.PMID: 16039645 [PubMed - indexed for MEDLINE]Related articles

An activin-A/C chimera exhibits activin and myostatin antagonistic properties.

Muenster U, Harrison CA, Donaldson C, Vale W, Fischer WH.

J Biol Chem. 2005 Nov 4;280(44):36626-32. Epub 2005 Aug 29.PMID: 16129674 [PubMed - indexed for MEDLINE]Related articlesFree article