Warning: The NCBI web site requires JavaScript to function. more...
Identification of non-muscle myosin heavy chain as a substrate for Cdk5 and tool for drug screening.
Jämsä A, Agerman K, Radesäter AC, Ottervald J, Malmström J, Hiller G, Liu G, Vasänge M.
J Biomed Sci. 2009 Jun 17;16:55.
Related citations
Glutamate treatment and p25 transfection increase Cdk5 mediated tau phosphorylation in SH-SY5Y cells.
Jämsä A, Bäckström A, Gustafsson E, Dehvari N, Hiller G, Cowburn RF, Vasänge M.
Biochem Biophys Res Commun. 2006 Jun 23;345(1):324-31. Epub 2006 May 6.
Different mechanisms of CDK5 and CDK2 activation as revealed by CDK5/p25 and CDK2/cyclin A dynamics.
Otyepka M, Bártová I, Kríz Z, Koca J.
J Biol Chem. 2006 Mar 17;281(11):7271-81. Epub 2006 Jan 9.
Protein kinase Cgamma regulates myosin IIB phosphorylation, cellular localization, and filament assembly.
Rosenberg M, Ravid S.
Mol Biol Cell. 2006 Mar;17(3):1364-74. Epub 2006 Jan 4.
Identification of novel substrates for Cdk5 and new targets for Cdk5 inhibitors using high-density protein microarrays.
Schnack C, Hengerer B, Gillardon F.
Proteomics. 2008 May;8(10):1980-6.
Increased expression of cdk5/p25 in N2a cells leads to hyperphosphorylation and impaired axonal transport of neurofilament proteins.
Zhou J, Wang H, Feng Y, Chen J.
Life Sci. 2010 Mar 27;86(13-14):532-7. Epub 2010 Feb 12.
Kinetic studies of Cdk5/p25 kinase: phosphorylation of tau and complex inhibition by two prototype inhibitors.
Liu M, Choi S, Cuny GD, Ding K, Dobson BC, Glicksman MA, Auerbach K, Stein RL.
Biochemistry. 2008 Aug 12;47(32):8367-77. Epub 2008 Jul 18.
Expression of non-muscle myosin heavy chain in rat heart after immunosuppressive treatment.
Rezzani R, Pompili E, Agostini C, Buffoli B, Bonomini F, Nori S, Fumagalli L, Bianchi R.
Int Immunopharmacol. 2006 Jun;6(6):962-7. Epub 2006 Feb 17.
Epidermal growth factor-mediated transient phosphorylation and membrane localization of myosin II-B are required for efficient chemotaxis.
Ben-Ya'acov A, Ravid S.
J Biol Chem. 2003 Oct 10;278(41):40032-40. Epub 2003 Jul 21.
The role of CDK5/P25 formation/inhibition in neurodegeneration.
Camins A, Verdaguer E, Folch J, Canudas AM, Pallàs M.
Drug News Perspect. 2006 Oct;19(8):453-60. Review.
CDK5 phosphorylates eNOS at Ser-113 and regulates NO production.
Lee CH, Wei YW, Huang YT, Lin YT, Lee YC, Lee KH, Lu PJ.
J Cell Biochem. 2010 May;110(1):112-7.
Mechanism of CDK5/p25 binding by CDK inhibitors.
Mapelli M, Massimiliano L, Crovace C, Seeliger MA, Tsai LH, Meijer L, Musacchio A.
J Med Chem. 2005 Feb 10;48(3):671-9.
Structure-activity relationships of 3,4-dihydro-1H-quinazolin-2-one derivatives as potential CDK5 inhibitors.
Rzasa RM, Kaller MR, Liu G, Magal E, Nguyen TT, Osslund TD, Powers D, Santora VJ, Viswanadhan VN, Wang HL, Xiong X, Zhong W, Norman MH.
Bioorg Med Chem. 2007 Oct 15;15(20):6574-95. Epub 2007 Jul 25.
Non-muscle myosin heavy chain IIA and IIB interact and co-localize in living cells: relevance for MYH9-related disease.
Marini M, Bruschi M, Pecci A, Romagnoli R, Musante L, Candiano G, Ghiggeri GM, Balduini C, Seri M, Ravazzolo R.
Int J Mol Med. 2006 May;17(5):729-36.
The D(3) dopamine receptor inhibits dopamine release in PC-12/hD3 cells by autoreceptor signaling via PP-2B, CK1, and Cdk-5.
Chen PC, Lao CL, Chen JC.
J Neurochem. 2009 Aug;110(4):1180-90. Epub 2009 Jun 9.
Cdk5 phosphorylates PLD2 to mediate EGF-dependent insulin secretion.
Lee HY, Jung H, Jang IH, Suh PG, Ryu SH.
Cell Signal. 2008 Oct;20(10):1787-94. Epub 2008 Jun 25.
Distinct functions of Cdk5(Y15) phosphorylation and Cdk5 activity in stress fiber formation and organization.
Qiao F, Gao CY, Tripathi BK, Zelenka PS.
Exp Cell Res. 2008 Nov 15;314(19):3542-50. Epub 2008 Sep 24.
PAK1 regulates myosin II-B phosphorylation, filament assembly, localization and cell chemotaxis.
Even-Faitelson L, Rosenberg M, Ravid S.
Cell Signal. 2005 Sep;17(9):1137-48. Epub 2005 Feb 26.
Identifying novel substrates for mouse Cdk5 kinase using the yeast Saccharomyces cerevisiae.
Horiuchi Y, Asada A, Hisanaga S, Toh-e A, Nishizawa M.
Genes Cells. 2006 Dec;11(12):1393-404.
New approaches to the discovery of cdk5 inhibitors.
Glicksman MA, Cuny GD, Liu M, Dobson B, Auerbach K, Stein RL, Kosik KS.
Curr Alzheimer Res. 2007 Dec;4(5):547-9. Review.
Filter your results:
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on