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    Results: 1 to 20 of 90

    1.

    Emerging role of LRRK2 in human neural progenitor cell cycle progression, survival and differentiation.

    Milosevic J, Schwarz SC, Ogunlade V, Meyer AK, Storch A, Schwarz J.

    Mol Neurodegener. 2009 Jun 15;4:25.

    PMID:
    19523245
    [PubMed - in process]
    Free PMC Article
    2.

    Molecular biology changes associated with LRRK2 mutations in Parkinson's disease.

    Lu YW, Tan EK.

    J Neurosci Res. 2008 Jul;86(9):1895-901. Review.

    PMID:
    18338801
    [PubMed - indexed for MEDLINE]
    3.

    Expression of the LRRK2 gene in the midbrain dopaminergic neurons of the substantia nigra.

    Han BS, Iacovitti L, Katano T, Hattori N, Seol W, Kim KS.

    Neurosci Lett. 2008 Sep 19;442(3):190-4. Epub 2008 Jul 10.

    PMID:
    18634852
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    LRRK2 expression in idiopathic and G2019S positive Parkinson's disease subjects: a morphological and quantitative study.

    Sharma S, Bandopadhyay R, Lashley T, Renton AE, Kingsbury AE, Kumaran R, Kallis C, Vilariño-Güell C, O'Sullivan SS, Lees AJ, Revesz T, Wood NW, Holton JL.

    Neuropathol Appl Neurobiol. 2011 Dec;37(7):777-90. doi: 10.1111/j.1365-2990.2011.01187.x.

    PMID:
    21696411
    [PubMed - in process]
    5.

    Leucine-rich repeat kinase 2 modulates retinoic acid-induced neuronal differentiation of murine embryonic stem cells.

    Schulz C, Paus M, Frey K, Schmid R, Kohl Z, Mennerich D, Winkler J, Gillardon F.

    PLoS One. 2011;6(6):e20820. Epub 2011 Jun 9.

    PMID:
    21695257
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    RNA interference of LRRK2-microarray expression analysis of a Parkinson's disease key player.

    Häbig K, Walter M, Poths S, Riess O, Bonin M.

    Neurogenetics. 2008 May;9(2):83-94. Epub 2007 Dec 21.

    PMID:
    18097693
    [PubMed - indexed for MEDLINE]
    7.

    Expression and localization of Parkinson's disease-associated leucine-rich repeat kinase 2 in the mouse brain.

    Higashi S, Moore DJ, Colebrooke RE, Biskup S, Dawson VL, Arai H, Dawson TM, Emson PC.

    J Neurochem. 2007 Jan;100(2):368-81. Epub 2006 Nov 13.

    PMID:
    17101029
    [PubMed - indexed for MEDLINE]
    8.

    Leucine-rich repeat kinase 2 is associated with the endoplasmic reticulum in dopaminergic neurons and accumulates in the core of Lewy bodies in Parkinson disease.

    Vitte J, Traver S, Maués De Paula A, Lesage S, Rovelli G, Corti O, Duyckaerts C, Brice A.

    J Neuropathol Exp Neurol. 2010 Sep;69(9):959-72.

    PMID:
    20720502
    [PubMed - indexed for MEDLINE]
    9.

    A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease.

    Melrose HL, Kent CB, Taylor JP, Dachsel JC, Hinkle KM, Lincoln SJ, Mok SS, Culvenor JG, Masters CL, Tyndall GM, Bass DI, Ahmed Z, Andorfer CA, Ross OA, Wszolek ZK, Delldonne A, Dickson DW, Farrer MJ.

    Neuroscience. 2007 Jul 29;147(4):1047-58. Epub 2007 Jul 3.

    PMID:
    17611037
    [PubMed - indexed for MEDLINE]
    10.

    Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice.

    Tong Y, Yamaguchi H, Giaime E, Boyle S, Kopan R, Kelleher RJ 3rd, Shen J.

    Proc Natl Acad Sci U S A. 2010 May 25;107(21):9879-84. Epub 2010 May 10.

    PMID:
    20457918
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    11.

    Curcumin exposure induces expression of the Parkinson's disease-associated leucine-rich repeat kinase 2 (LRRK2) in rat mesencephalic cells.

    Ortiz-Ortiz MA, Morán JM, Ruiz-Mesa LM, Niso-Santano M, Bravo-SanPedro JM, Gómez-Sánchez R, González-Polo RA, Fuentes JM.

    Neurosci Lett. 2010 Jan 4;468(2):120-4. Epub 2009 Oct 30.

    PMID:
    19879924
    [PubMed - indexed for MEDLINE]
    12.

    Anatomical localization of leucine-rich repeat kinase 2 in mouse brain.

    Melrose H, Lincoln S, Tyndall G, Dickson D, Farrer M.

    Neuroscience. 2006;139(3):791-4. Epub 2006 Feb 28.

    PMID:
    16504409
    [PubMed - indexed for MEDLINE]
    13.

    On the road to leucine-rich repeat kinase 2 signalling: evidence from cellular and in vivo studies.

    Daniëls V, Baekelandt V, Taymans JM.

    Neurosignals. 2011;19(1):1-15. Epub 2011 Mar 23. Review.

    PMID:
    21430363
    [PubMed - indexed for MEDLINE]
    14.

    Dysregulated LRRK2 signaling in response to endoplasmic reticulum stress leads to dopaminergic neuron degeneration in C. elegans.

    Yuan Y, Cao P, Smith MA, Kramp K, Huang Y, Hisamoto N, Matsumoto K, Hatzoglou M, Jin H, Feng Z.

    PLoS One. 2011;6(8):e22354. Epub 2011 Aug 3.

    PMID:
    21857923
    [PubMed - in process]
    Free PMC Article
    15.

    Expression of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibits the Processing of uMtCK to Induce Cell Death in cell culture model system.

    Cui J, Yu M, Niu J, Yue Z, Xu Z.

    Biosci Rep. 2011 Mar 4. [Epub ahead of print]

    PMID:
    21370995
    [PubMed - as supplied by publisher]
    16.

    Developmental regulation of leucine-rich repeat kinase 1 and 2 expression in the brain and other rodent and human organs: Implications for Parkinson's disease.

    Westerlund M, Belin AC, Anvret A, Bickford P, Olson L, Galter D.

    Neuroscience. 2008 Mar 18;152(2):429-36. Epub 2008 Jan 10.

    PMID:
    18272292
    [PubMed - indexed for MEDLINE]
    17.

    Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration.

    Smith WW, Pei Z, Jiang H, Moore DJ, Liang Y, West AB, Dawson VL, Dawson TM, Ross CA.

    Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18676-81. Epub 2005 Dec 13.

    PMID:
    16352719
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.

    Leucine-rich repeat kinase 2 associates with lipid rafts.

    Hatano T, Kubo S, Imai S, Maeda M, Ishikawa K, Mizuno Y, Hattori N.

    Hum Mol Genet. 2007 Mar 15;16(6):678-90. Epub 2007 Mar 6.

    PMID:
    17341485
    [PubMed - indexed for MEDLINE]
    Free Article
    19.

    Temporal expression of mutant LRRK2 in adult rats impairs dopamine reuptake.

    Zhou H, Huang C, Tong J, Hong WC, Liu YJ, Xia XG.

    Int J Biol Sci. 2011;7(6):753-61. Epub 2011 Jun 9.

    PMID:
    21698001
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    20.

    LRRK2 and neurodegeneration.

    Santpere G, Ferrer I.

    Acta Neuropathol. 2009 Mar;117(3):227-46. Epub 2009 Jan 14. Review.

    PMID:
    19142648
    [PubMed - indexed for MEDLINE]

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