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    Results: 1 to 20 of 97

    1.

    Inhaled activated protein C: a novel therapy for acute lung injury?

    Liu KD, Looney MR, Matthay MA.

    Crit Care. 2009;13(3):150. Epub 2009 May 21.PMID: 19519935 [PubMed - indexed for MEDLINE]Related articles

    2.

    Inhaled aerosolised recombinant human activated protein C ameliorates endotoxin-induced lung injury in anaesthetised sheep.

    Waerhaug K, Kuzkov VV, Kuklin VN, Mortensen R, Nordhus KC, Kirov MY, Bjertnaes LJ.

    Crit Care. 2009;13(2):R51. Epub 2009 Apr 8.PMID: 19356243 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Inhaled activated protein C attenuates lung injury induced by aerosolized endotoxin in mice.

    Kotanidou A, Loutrari H, Papadomichelakis E, Glynos C, Magkou C, Armaganidis A, Papapetropoulos A, Roussos C, Orfanos SE.

    Vascul Pharmacol. 2006 Aug;45(2):134-40. Epub 2006 Jul 25.PMID: 16959545 [PubMed - indexed for MEDLINE]Related articles

    4.

    Intravenous administration of activated protein C in Pseudomonas-induced lung injury: impact on lung fluid balance and the inflammatory response.

    Robriquet L, Collet F, Tournoys A, Prangère T, Nevière R, Fourrier F, Guery BP.

    Respir Res. 2006 Mar 22;7:41.PMID: 16553944 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Recombinant human activated protein C ameliorates oleic acid-induced lung injury in awake sheep.

    Waerhaug K, Kirov MY, Kuzkov VV, Kuklin VN, Bjertnaes LJ.

    Crit Care. 2008;12(6):R146. Epub 2008 Nov 20.PMID: 19021914 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Inhaled milrinone attenuates experimental acute lung injury.

    Bueltmann M, Kong X, Mertens M, Yin N, Yin J, Liu Z, Koster A, Kuppe H, Kuebler WM.

    Intensive Care Med. 2009 Jan;35(1):171-8. Epub 2008 Oct 30.PMID: 18972099 [PubMed - indexed for MEDLINE]Related articles

    7.

    Recombinant human activated protein C attenuates endotoxin-induced lung injury in awake sheep.

    Waerhaug K, Kuklin VN, Kirov MY, Sovershaev MA, Langbakk B, Ingebretsen OC, Ytrehus K, Bjertnaes LJ.

    Crit Care. 2008;12(4):R104. Epub 2008 Aug 15.PMID: 18702832 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Effects of activated protein C on coagulation and fibrinolysis in rabbits with endotoxin induced acute lung injury.

    He HY, Wang C, Pang BS.

    Chin Med J (Engl). 2008 Dec 20;121(24):2561-5.PMID: 19187596 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Recombinant human activated protein C improves pulmonary function in ovine acute lung injury resulting from smoke inhalation and sepsis.

    Maybauer MO, Maybauer DM, Fraser JF, Traber LD, Westphal M, Enkhbaatar P, Cox RA, Huda R, Hawkins HK, Morita N, Murakami K, Mizutani A, Herndon DN, Traber DL.

    Crit Care Med. 2006 Sep;34(9):2432-8.PMID: 16810106 [PubMed - indexed for MEDLINE]Related articles

    10.

    Effect of activated protein C on pulmonary blood flow and cytokine production in experimental acute lung injury.

    Richard JC, Bregeon F, Leray V, Le Bars D, Costes N, Tourvieille C, Lavenne F, Devouassoux-Shisheboran M, Gimenez G, Guerin C.

    Intensive Care Med. 2007 Dec;33(12):2199-206. Epub 2007 Aug 2.PMID: 17671779 [PubMed - indexed for MEDLINE]Related articles

    11.

    Activated protein C attenuates intestinal reperfusion-induced acute lung injury: an experimental study in a rat model.

    Teke Z, Sacar M, Yenisey C, Atalay AO, Bicakci T, Erdem E.

    Am J Surg. 2008 Jun;195(6):861-73.PMID: 18367148 [PubMed - indexed for MEDLINE]Related articles

    12.

    Combined anticoagulants ameliorate acute lung injury in sheep after burn and smoke inhalation.

    Enkhbaatar P, Esechie A, Wang J, Cox RA, Nakano Y, Hamahata A, Lange M, Traber LD, Prough DS, Herndon DN, Traber DL.

    Clin Sci (Lond). 2008 Feb;114(4):321-9.PMID: 17927568 [PubMed - indexed for MEDLINE]Related articles

    13.

    Recombinant human activated protein C (rhAPC; drotrecogin alfa [activated]) has minimal effect on markers of coagulation, fibrinolysis, and inflammation in acute human endotoxemia.

    Derhaschnig U, Reiter R, Knöbl P, Baumgartner M, Keen P, Jilma B.

    Blood. 2003 Sep 15;102(6):2093-8. Epub 2003 May 15.PMID: 12750166 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Activated human protein C prevents thrombin-induced thromboembolism in mice. Evidence that activated protein c reduces intravascular fibrin accumulation through the inhibition of additional thrombin generation.

    Gresele P, Momi S, Berrettini M, Nenci GG, Schwarz HP, Semeraro N, Colucci M.

    J Clin Invest. 1998 Feb 1;101(3):667-76.PMID: 9449701 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Activated protein C inhibits local coagulation after intrapulmonary delivery of endotoxin in humans.

    van der Poll T, Levi M, Nick JA, Abraham E.

    Am J Respir Crit Care Med. 2005 May 15;171(10):1125-8. Epub 2005 Mar 4.PMID: 15750041 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Effects of inhaled nitric oxide and extracorporeal membrane oxygenation on pulmonary hemodynamics and lymph flow in oleic acid lung injury in sheep.

    Germann P, Balassa A, Roeder G, Kaider A, Schlag G, Zimpfer M, Sladen R.

    Crit Care Med. 1997 Nov;25(11):1881-7.PMID: 9366774 [PubMed - indexed for MEDLINE]Related articles

    17.

    Anticoagulant therapy in acute lung injury: a useful tool without proper operating instruction?

    Rehberg S, Enkhbaatar P, Traber DL.

    Crit Care. 2008;12(5):179. Epub 2008 Sep 22.PMID: 18828885 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Role of coagulation pathways and treatment with activated protein C in hyperoxic lung injury.

    Looney MR, Esmon CT, Matthay MA.

    Thorax. 2009 Feb;64(2):114-20. Epub 2008 Nov 13.PMID: 19008297 [PubMed - indexed for MEDLINE]Related articles

    19.

    Randomized clinical trial of activated protein C for the treatment of acute lung injury.

    Liu KD, Levitt J, Zhuo H, Kallet RH, Brady S, Steingrub J, Tidswell M, Siegel MD, Soto G, Peterson MW, Chesnutt MS, Phillips C, Weinacker A, Thompson BT, Eisner MD, Matthay MA.

    Am J Respir Crit Care Med. 2008 Sep 15;178(6):618-23. Epub 2008 Jun 19.PMID: 18565951 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Recombinant human activated protein C inhibits local and systemic activation of coagulation without influencing inflammation during Pseudomonas aeruginosa pneumonia in rats.

    Choi G, Hofstra JJ, Roelofs JJ, Florquin S, Bresser P, Levi M, van der Poll T, Schultz MJ.

    Crit Care Med. 2007 May;35(5):1362-8.PMID: 17414732 [PubMed - indexed for MEDLINE]Related articles

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