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    Results: 1 to 20 of 477

    1.

    N-ethyl-N-nitrosourea mutagenesis produced a small number of mice with altered plasma electrolyte levels.

    Aigner B, Rathkolb B, Klempt M, Wagner S, Michel D, de Angelis MH, Wolf E.

    J Biomed Sci. 2009 Jun 8;16:53.

    PMID:
    19505327
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in plasma enzyme activities as novel organ-specific disease models.

    Aigner B, Rathkolb B, Klaften M, Sedlmeier R, Klempt M, Wagner S, Michel D, Mayer U, Klopstock T, de Angelis MH, Wolf E.

    Exp Physiol. 2009 Apr;94(4):412-21. Epub 2009 Jan 16.

    PMID:
    19151073
    [PubMed - indexed for MEDLINE]
    Free Article
    3.

    Generation of ENU-induced mouse mutants with hypocholesterolemia: novel tools for dissecting plasma lipoprotein homeostasis.

    Aigner B, Rathkolb B, Mohr M, Klempt M, Hrabé de Angelis M, Wolf E.

    Lipids. 2007 Aug;42(8):731-7. Epub 2007 Jun 7.

    PMID:
    17554576
    [PubMed - indexed for MEDLINE]
    4.

    Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in hematological parameters.

    Aigner B, Rathkolb B, Klempt M, Wagner S, Michel D, Klaften M, Laufs J, Schneider B, Sedlmeier R, Hrabé de Angelis M, Wolf E.

    Mamm Genome. 2011 Oct;22(9-10):495-505. Epub 2011 May 8.

    PMID:
    21553221
    [PubMed - indexed for MEDLINE]
    5.

    Hypercholesterolemia in ENU-induced mouse mutants.

    Mohr M, Klempt M, Rathkolb B, de Angelis MH, Wolf E, Aigner B.

    J Lipid Res. 2004 Nov;45(11):2132-7. Epub 2004 Sep 1.

    PMID:
    15342683
    [PubMed - indexed for MEDLINE]
    Free Article
    6.

    Screening for increased plasma urea levels in a large-scale ENU mouse mutagenesis project reveals kidney disease models.

    Aigner B, Rathkolb B, Herbach N, Kemter E, Schessl C, Klaften M, Klempt M, de Angelis MH, Wanke R, Wolf E.

    Am J Physiol Renal Physiol. 2007 May;292(5):F1560-7. Epub 2007 Jan 30.

    PMID:
    17264314
    [PubMed - indexed for MEDLINE]
    Free Article
    7.

    A genomewide screening of N-ethyl-N-nitrosourea-mutagenized mice for musculoskeletal phenotypes.

    Srivastava AK, Mohan S, Wergedal JE, Baylink DJ.

    Bone. 2003 Aug;33(2):179-91.

    PMID:
    14499351
    [PubMed - indexed for MEDLINE]
    8.

    Enu mouse mutagenesis: generation of mouse mutants with aberrant plasma IgE levels.

    Alessandrini F, Jakob T, Wolf A, Wolf E, Balling R, Hrabé de Angelis M, Ring J, Behrendt H.

    Int Arch Allergy Immunol. 2001 Jan-Mar;124(1-3):25-8.

    PMID:
    11306917
    [PubMed - indexed for MEDLINE]
    9.

    N-ethyl-N-nitrosourea-based generation of mouse models for mutant G protein-coupled receptors.

    Grosse J, Tarnow P, Römpler H, Schneider B, Sedlmeier R, Huffstadt U, Korthaus D, Nehls M, Wattler S, Schöneberg T, Biebermann H, Augustin M.

    Physiol Genomics. 2006 Aug 16;26(3):209-17. Epub 2006 May 23.

    PMID:
    16720677
    [PubMed - indexed for MEDLINE]
    Free Article
    10.

    Analysis of breeding and pathology helps refine management practices of a large-scale N'-ethyl-N'-nitrosourea mouse mutagenesis programme.

    Smith AP, Polley S, Wells S, Stewart M, Vizor L, Humphreys J, Warren MV, Dear N, Cheeseman MT.

    Lab Anim. 2009 Jan;43(1):1-10. Epub 2008 Nov 5.

    PMID:
    18987059
    [PubMed - indexed for MEDLINE]
    11.

    Novel phenotypes identified by plasma biochemical screening in the mouse.

    Hough TA, Nolan PM, Tsipouri V, Toye AA, Gray IC, Goldsworthy M, Moir L, Cox RD, Clements S, Glenister PH, Wood J, Selley RL, Strivens MA, Vizor L, McCormack SL, Peters J, Fisher EM, Spurr N, Rastan S, Martin JE, Brown SD, Hunter AJ.

    Mamm Genome. 2002 Oct;13(10):595-602.

    PMID:
    12420138
    [PubMed - indexed for MEDLINE]
    12.

    Novel mouse mutants with primary cellular immunodeficiencies generated by genome-wide mutagenesis.

    Jakob T, Köllisch GV, Howaldt M, Bewersdorff M, Rathkolb B, Müller ML, Sandholzer N, Nitschke L, Schiemann M, Mempel M, Ollert M, Neubauer A, Soewarto DA, Kremmer E, Ring J, Behrendt H, Flaswinkel H.

    J Allergy Clin Immunol. 2008 Jan;121(1):179-184.e7. Epub 2007 Sep 4.

    PMID:
    17767948
    [PubMed - indexed for MEDLINE]
    13.

    A phenotype-driven ENU mutagenesis screen for the identification of dominant mutations involved in alcohol consumption.

    Pawlak CR, Sanchis-Segura C, Soewarto D, Wagner S, Hrabé de Angelis M, Spanagel R.

    Mamm Genome. 2008 Feb;19(2):77-84. Epub 2008 Jan 23.

    PMID:
    18213483
    [PubMed - indexed for MEDLINE]
    14.

    Diabetes models by screen for hyperglycemia in phenotype-driven ENU mouse mutagenesis projects.

    Aigner B, Rathkolb B, Herbach N, Hrabé de Angelis M, Wanke R, Wolf E.

    Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E232-40. Epub 2007 Dec 4. Review.

    PMID:
    18056790
    [PubMed - indexed for MEDLINE]
    Free Article
    15.

    Optimizing screening and mating strategies for phenotype-driven recessive N-ethyl-N-nitrosourea screens in mice.

    Barbaric I, Dear TN.

    J Am Assoc Lab Anim Sci. 2007 Nov;46(6):44-9.

    PMID:
    17994672
    [PubMed - indexed for MEDLINE]
    17.

    A series of maturity onset diabetes of the young, type 2 (MODY2) mouse models generated by a large-scale ENU mutagenesis program.

    Inoue M, Sakuraba Y, Motegi H, Kubota N, Toki H, Matsui J, Toyoda Y, Miwa I, Terauchi Y, Kadowaki T, Shigeyama Y, Kasuga M, Adachi T, Fujimoto N, Matsumoto R, Tsuchihashi K, Kagami T, Inoue A, Kaneda H, Ishijima J, Masuya H, Suzuki T, Wakana S, Gondo Y, Minowa O, Shiroishi T, Noda T.

    Hum Mol Genet. 2004 Jun 1;13(11):1147-57. Epub 2004 Apr 21.

    PMID:
    15102714
    [PubMed - indexed for MEDLINE]
    Free Article
    18.

    Inducing mutations in the mouse genome with the chemical mutagen ethylnitrosourea.

    Massironi SM, Reis BL, Carneiro JG, Barbosa LB, Ariza CB, Santos GC, Guénet JL, Godard AL.

    Braz J Med Biol Res. 2006 Sep;39(9):1217-26.

    PMID:
    16972005
    [PubMed - indexed for MEDLINE]
    Free Article
    19.

    Spectrum of ENU-induced mutations in phenotype-driven and gene-driven screens in the mouse.

    Barbaric I, Wells S, Russ A, Dear TN.

    Environ Mol Mutagen. 2007 Mar;48(2):124-42.

    PMID:
    17295309
    [PubMed - indexed for MEDLINE]
    20.

    Estimating the number of coding mutations in genotypic- and phenotypic-driven N-ethyl-N-nitrosourea (ENU) screens.

    Keays DA, Clark TG, Flint J.

    Mamm Genome. 2006 Mar;17(3):230-8. Epub 2006 Mar 3.

    PMID:
    16518690
    [PubMed - indexed for MEDLINE]

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