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    Results: 1 to 20 of 310

    1.

    Long-term activation of TLR3 by poly(I:C) induces inflammation and impairs lung function in mice.

    Stowell NC, Seideman J, Raymond HA, Smalley KA, Lamb RJ, Egenolf DD, Bugelski PJ, Murray LA, Marsters PA, Bunting RA, Flavell RA, Alexopoulou L, San Mateo LR, Griswold DE, Sarisky RT, Mbow ML, Das AM.

    Respir Res. 2009 Jun 1;10:43.PMID: 19486528 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Synthetic double-stranded RNA induces multiple genes related to inflammation through Toll-like receptor 3 depending on NF-kappaB and/or IRF-3 in airway epithelial cells.

    Matsukura S, Kokubu F, Kurokawa M, Kawaguchi M, Ieki K, Kuga H, Odaka M, Suzuki S, Watanabe S, Takeuchi H, Kasama T, Adachi M.

    Clin Exp Allergy. 2006 Aug;36(8):1049-62.PMID: 16911361 [PubMed - indexed for MEDLINE]Related articles

    3.

    Activation of toll-like receptor 3 protects against DSS-induced acute colitis.

    Vijay-Kumar M, Wu H, Aitken J, Kolachala VL, Neish AS, Sitaraman SV, Gewirtz AT.

    Inflamm Bowel Dis. 2007 Jul;13(7):856-64.PMID: 17393379 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Microglia recognize double-stranded RNA via TLR3.

    Town T, Jeng D, Alexopoulou L, Tan J, Flavell RA.

    J Immunol. 2006 Mar 15;176(6):3804-12.PMID: 16517751 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Key differences in TLR3/poly I:C signaling and cytokine induction by human primary cells: a phenomenon absent from murine cell systems.

    Lundberg AM, Drexler SK, Monaco C, Williams LM, Sacre SM, Feldmann M, Foxwell BM.

    Blood. 2007 Nov 1;110(9):3245-52. Epub 2007 Jul 27.PMID: 17660379 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Characterization of Toll-like receptors in primary lung epithelial cells: strong impact of the TLR3 ligand poly(I:C) on the regulation of Toll-like receptors, adaptor proteins and inflammatory response.

    Ritter M, Mennerich D, Weith A, Seither P.

    J Inflamm (Lond). 2005 Nov 29;2:16.PMID: 16316467 [PubMed]Related articlesFree article

    7.

    TLR3 is essential for the induction of protective immunity against Punta Toro Virus infection by the double-stranded RNA (dsRNA), poly(I:C12U), but not Poly(I:C): differential recognition of synthetic dsRNA molecules.

    Gowen BB, Wong MH, Jung KH, Sanders AB, Mitchell WM, Alexopoulou L, Flavell RA, Sidwell RW.

    J Immunol. 2007 Apr 15;178(8):5200-8.PMID: 17404303 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    TLR3 activation stimulates cytokine secretion without altering agonist-induced human small airway contraction or relaxation.

    Cooper PR, Lamb R, Day ND, Branigan PJ, Kajekar R, San Mateo L, Hornby PJ, Panettieri RA Jr.

    Am J Physiol Lung Cell Mol Physiol. 2009 Sep;297(3):L530-7. Epub 2009 Jun 19.PMID: 19542247 [PubMed - indexed for MEDLINE]Related articles

    9.

    Deletion of TLR3 alters the pulmonary immune environment and mucus production during respiratory syncytial virus infection.

    Rudd BD, Smit JJ, Flavell RA, Alexopoulou L, Schaller MA, Gruber A, Berlin AA, Lukacs NW.

    J Immunol. 2006 Feb 1;176(3):1937-42.PMID: 16424225 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Diesel exhaust enhances virus- and poly(I:C)-induced Toll-like receptor 3 expression and signaling in respiratory epithelial cells.

    Ciencewicki J, Brighton L, Wu WD, Madden M, Jaspers I.

    Am J Physiol Lung Cell Mol Physiol. 2006 Jun;290(6):L1154-63. Epub 2006 Jan 6.PMID: 16399790 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    TLR3: interferon induction by double-stranded RNA including poly(I:C).

    Matsumoto M, Seya T.

    Adv Drug Deliv Rev. 2008 Apr 29;60(7):805-12. Epub 2008 Jan 2. Review.PMID: 18262679 [PubMed - indexed for MEDLINE]Related articles

    12.

    Respiratory syncytial virus induces TLR3 protein and protein kinase R, leading to increased double-stranded RNA responsiveness in airway epithelial cells.

    Groskreutz DJ, Monick MM, Powers LS, Yarovinsky TO, Look DC, Hunninghake GW.

    J Immunol. 2006 Feb 1;176(3):1733-40.PMID: 16424203 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells.

    McCartney S, Vermi W, Gilfillan S, Cella M, Murphy TL, Schreiber RD, Murphy KM, Colonna M.

    J Exp Med. 2009 Dec 21;206(13):2967-76. Epub 2009 Dec 7.PMID: 19995959 [PubMed - indexed for MEDLINE]Related articles

    14.

    Double-stranded RNA induces iNOS gene expression in Schwann cells, sensory neuronal death, and peripheral nerve demyelination.

    Lee H, Park C, Cho IH, Kim HY, Jo EK, Lee S, Kho HS, Choi SY, Oh SB, Park K, Kim JS, Lee SJ.

    Glia. 2007 May;55(7):712-22.PMID: 17348024 [PubMed - indexed for MEDLINE]Related articles

    15.

    Alteration of TLR3 pathways by glucocorticoids may be responsible for immunosusceptibility of human corneal epithelial cells to viral infections.

    Hara Y, Shiraishi A, Kobayashi T, Kadota Y, Shirakata Y, Hashimoto K, Ohashi Y.

    Mol Vis. 2009 May 8;15:937-48.PMID: 19452017 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    The sickness behaviour and CNS inflammatory mediator profile induced by systemic challenge of mice with synthetic double-stranded RNA (poly I:C).

    Cunningham C, Campion S, Teeling J, Felton L, Perry VH.

    Brain Behav Immun. 2007 May;21(4):490-502. Epub 2007 Feb 26.PMID: 17321719 [PubMed - indexed for MEDLINE]Related articles

    17.

    Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways.

    Dogusan Z, García M, Flamez D, Alexopoulou L, Goldman M, Gysemans C, Mathieu C, Libert C, Eizirik DL, Rasschaert J.

    Diabetes. 2008 May;57(5):1236-45. Epub 2008 Jan 25.PMID: 18223009 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Human TSLP and TLR3 ligands promote differentiation of Th17 cells with a central memory phenotype under Th2-polarizing conditions.

    Tanaka J, Watanabe N, Kido M, Saga K, Akamatsu T, Nishio A, Chiba T.

    Clin Exp Allergy. 2009 Jan;39(1):89-100. Epub 2008 Dec 1.PMID: 19055649 [PubMed - indexed for MEDLINE]Related articles

    19.

    Activation of TLR3 in the trophoblast is associated with preterm delivery.

    Koga K, Cardenas I, Aldo P, Abrahams VM, Peng B, Fill S, Romero R, Mor G.

    Am J Reprod Immunol. 2009 Mar;61(3):196-212.PMID: 19239422 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virus-induced acute pneumonia.

    Le Goffic R, Balloy V, Lagranderie M, Alexopoulou L, Escriou N, Flavell R, Chignard M, Si-Tahar M.

    PLoS Pathog. 2006 Jun;2(6):e53. Epub 2006 Jun 9.PMID: 16789835 [PubMed - indexed for MEDLINE]Related articlesFree article

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