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    Results: 1 to 20 of 114

    1.

    Hypoxia. Hypoxia in the pathogenesis of systemic sclerosis.

    Beyer C, Schett G, Gay S, Distler O, Distler JH.

    Arthritis Res Ther. 2009;11(2):220. Epub 2009 Apr 21. Review.

    PMID:
    19473554
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Hypoxia-induced increase in the production of extracellular matrix proteins in systemic sclerosis.

    Distler JH, Jüngel A, Pileckyte M, Zwerina J, Michel BA, Gay RE, Kowal-Bielecka O, Matucci-Cerinic M, Schett G, Marti HH, Gay S, Distler O.

    Arthritis Rheum. 2007 Dec;56(12):4203-15.

    PMID:
    18050252
    [PubMed - indexed for MEDLINE]
    Free Article
    3.

    Uncontrolled expression of vascular endothelial growth factor and its receptors leads to insufficient skin angiogenesis in patients with systemic sclerosis.

    Distler O, Distler JH, Scheid A, Acker T, Hirth A, Rethage J, Michel BA, Gay RE, Müller-Ladner U, Matucci-Cerinic M, Plate KH, Gassmann M, Gay S.

    Circ Res. 2004 Jul 9;95(1):109-16. Epub 2004 Jun 3.

    PMID:
    15178641
    [PubMed - indexed for MEDLINE]
    Free Article
    4.

    Overexpression of VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, leads to insufficient angiogenesis in patients with systemic sclerosis.

    Manetti M, Guiducci S, Romano E, Ceccarelli C, Bellando-Randone S, Conforti ML, Ibba-Manneschi L, Matucci-Cerinic M.

    Circ Res. 2011 Jul 22;109(3):e14-26. Epub 2011 Jun 2.

    PMID:
    21636803
    [PubMed - indexed for MEDLINE]
    5.

    Angiogenesis in systemic sclerosis: impaired expression of vascular endothelial growth factor receptor 1 in endothelial progenitor-derived cells under hypoxic conditions.

    Avouac J, Wipff J, Goldman O, Ruiz B, Couraud PO, Chiocchia G, Kahan A, Boileau C, Uzan G, Allanore Y.

    Arthritis Rheum. 2008 Nov;58(11):3550-61.

    PMID:
    18975312
    [PubMed - indexed for MEDLINE]
    Free Article
    6.

    Angiogenesis and vasculogenesis in systemic sclerosis.

    Distler JH, Gay S, Distler O.

    Rheumatology (Oxford). 2006 Oct;45 Suppl 3:iii26-7. Review. Erratum in: Rheumatology (Oxford). 2008 Feb;47(2):234-5.

    PMID:
    16987827
    [PubMed - indexed for MEDLINE]
    Free Article
    7.

    Scleroderma, fibroblasts, signaling, and excessive extracellular matrix.

    Ihn H.

    Curr Rheumatol Rep. 2005 Apr;7(2):156-62. Review.

    PMID:
    15760596
    [PubMed - indexed for MEDLINE]
    8.

    Hypoxia induces expression of connective tissue growth factor in scleroderma skin fibroblasts.

    Hong KH, Yoo SA, Kang SS, Choi JJ, Kim WU, Cho CS.

    Clin Exp Immunol. 2006 Nov;146(2):362-70.

    PMID:
    17034590
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    9.

    Systemic sclerosis fibroblasts inhibit in vitro angiogenesis by MMP-12-dependent cleavage of the endothelial cell urokinase receptor.

    Serratì S, Cinelli M, Margheri F, Guiducci S, Del Rosso A, Pucci M, Fibbi G, Bazzichi L, Bombardieri S, Matucci-Cerinic M, Del Rosso M.

    J Pathol. 2006 Oct;210(2):240-8.

    PMID:
    16917801
    [PubMed - indexed for MEDLINE]
    10.

    [Vascular changes in the pathogenesis of systemic sclerosis].

    Distler JH, Kalden JR, Gray S, Distler O.

    Z Rheumatol. 2004 Dec;63(6):446-50. Review. German.

    PMID:
    15605207
    [PubMed - indexed for MEDLINE]
    11.

    The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis.

    Reich N, Maurer B, Akhmetshina A, Venalis P, Dees C, Zerr P, Palumbo K, Zwerina J, Nevskaya T, Gay S, Distler O, Schett G, Distler JH.

    Arthritis Rheum. 2010 Jan;62(1):280-90.

    PMID:
    20039427
    [PubMed - indexed for MEDLINE]
    Free Article
    12.

    Cellular players in angiogenesis during the course of systemic sclerosis.

    Cipriani P, Marrelli A, Liakouli V, Di Benedetto P, Giacomelli R.

    Autoimmun Rev. 2011 Aug;10(10):641-6. Epub 2011 Apr 22. Review.

    PMID:
    21549220
    [PubMed - indexed for MEDLINE]
    13.

    Fibroblast response to hypoxia: the relationship between angiogenesis and matrix regulation.

    Steinbrech DS, Longaker MT, Mehrara BJ, Saadeh PB, Chin GS, Gerrets RP, Chau DC, Rowe NM, Gittes GK.

    J Surg Res. 1999 Jun 15;84(2):127-33.

    PMID:
    10357908
    [PubMed - indexed for MEDLINE]
    14.

    Urokinase receptor expression on human microvascular endothelial cells is increased by hypoxia: implications for capillary-like tube formation in a fibrin matrix.

    Kroon ME, Koolwijk P, van der Vecht B, van Hinsbergh VW.

    Blood. 2000 Oct 15;96(8):2775-83.

    PMID:
    11023511
    [PubMed - indexed for MEDLINE]
    Free Article
    15.

    Pathogenesis of scleroderma. Collagen.

    Jimenez SA, Hitraya E, Varga J.

    Rheum Dis Clin North Am. 1996 Nov;22(4):647-74. Review.

    PMID:
    8923589
    [PubMed - indexed for MEDLINE]
    16.

    [Systemic sclerosis and scleroderma circumscripta--disturbances of selected serum parameters which are responsible for vascular changes and CD34 expression in involved skin].

    Dziankowska-Bartkowiak B, Zebrowska A, Wagrowska-Danielewicz M, Kobos J, Waszczykowska E.

    Przegl Lek. 2009;66(12):1040-5. Polish.

    PMID:
    20514902
    [PubMed - indexed for MEDLINE]
    17.

    Angiotensin II in the lesional skin of systemic sclerosis patients contributes to tissue fibrosis via angiotensin II type 1 receptors.

    Kawaguchi Y, Takagi K, Hara M, Fukasawa C, Sugiura T, Nishimagi E, Harigai M, Kamatani N.

    Arthritis Rheum. 2004 Jan;50(1):216-26.

    PMID:
    14730619
    [PubMed - indexed for MEDLINE]
    Free Article
    18.

    Autocrine TGF-beta signaling in the pathogenesis of systemic sclerosis.

    Ihn H.

    J Dermatol Sci. 2008 Feb;49(2):103-13. Epub 2007 Jul 12. Review.

    PMID:
    17628443
    [PubMed - indexed for MEDLINE]
    19.

    Impairment of endothelial cell differentiation from bone marrow-derived mesenchymal stem cells: new insight into the pathogenesis of systemic sclerosis.

    Cipriani P, Guiducci S, Miniati I, Cinelli M, Urbani S, Marrelli A, Dolo V, Pavan A, Saccardi R, Tyndall A, Giacomelli R, Cerinic MM.

    Arthritis Rheum. 2007 Jun;56(6):1994-2004.

    PMID:
    17530639
    [PubMed - indexed for MEDLINE]
    Free Article
    20.

    [Hypoxia and angiogenesis in rheumatic diseases].

    Distler K.

    Z Rheumatol. 2003;62(Suppl 2):II43-5. German.

    PMID:
    14648091
    [PubMed - indexed for MEDLINE]

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