Warning: The NCBI web site requires JavaScript to function. more...
Mapping the sequence mutations of the 2009 H1N1 influenza A virus neuraminidase relative to drug and antibody binding sites.
Maurer-Stroh S, Ma J, Lee RT, Sirota FL, Eisenhaber F.
Biol Direct. 2009 May 20;4:18; discussion 18.
Related citations
Insights from investigating the interaction of oseltamivir (Tamiflu) with neuraminidase of the 2009 H1N1 swine flu virus.
Wang SQ, Du QS, Huang RB, Zhang DW, Chou KC.
Biochem Biophys Res Commun. 2009 Aug 28;386(3):432-6. Epub 2009 Jun 10.
Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Collins PJ, Haire LF, Lin YP, Liu J, Russell RJ, Walker PA, Skehel JJ, Martin SR, Hay AJ, Gamblin SJ.
Nature. 2008 Jun 26;453(7199):1258-61. Epub 2008 May 14.
Antiviral susceptibility of avian and swine influenza virus of the N1 neuraminidase subtype.
Stoner TD, Krauss S, DuBois RM, Negovetich NJ, Stallknecht DE, Senne DA, Gramer MR, Swafford S, DeLiberto T, Govorkova EA, Webster RG.
J Virol. 2010 Oct;84(19):9800-9. Epub 2010 Jul 21.
Computational analysis and determination of a highly conserved surface exposed segment in H5N1 avian flu and H1N1 swine flu neuraminidase.
Ghosh A, Nandy A, Nandy P.
BMC Struct Biol. 2010 Feb 22;10:6.
Host cell selection of influenza neuraminidase variants: implications for drug resistance monitoring in A(H1N1) viruses.
Okomo-Adhiambo M, Nguyen HT, Sleeman K, Sheu TG, Deyde VM, Garten RJ, Xu X, Shaw MW, Klimov AI, Gubareva LV.
Antiviral Res. 2010 Feb;85(2):381-8. Epub 2009 Nov 13.
Molecular dynamics simulations suggest that electrostatic funnel directs binding of Tamiflu to influenza N1 neuraminidases.
Le L, Lee EH, Hardy DJ, Truong TN, Schulten K.
PLoS Comput Biol. 2010 Sep 23;6(9). pii: e1000939.
Genetic characterization of circulating seasonal Influenza A viruses (2005-2009) revealed introduction of oseltamivir resistant H1N1 strains during 2009 in eastern India.
Agrawal AS, Sarkar M, Ghosh S, Roy T, Chakrabarti S, Lal R, Mishra AC, Chadha MS, Chawla-Sarkar M.
Infect Genet Evol. 2010 Dec;10(8):1188-98. Epub 2010 Aug 1.
Modeling gene sequences over time in 2009 H1N1 influenza A virus populations.
Goñi N, Fajardo A, Moratorio G, Colina R, Cristina J.
Virol J. 2009 Dec 4;6:215.
Homology modeling, docking, and molecular dynamics reveal HR1039 as a potent inhibitor of 2009 A(H1N1) influenza neuraminidase.
Wang YT, Chan CH, Su ZY, Chen CL.
Biophys Chem. 2010 Mar;147(1-2):74-80. Epub 2009 Dec 6.
Impact of neuraminidase mutations conferring influenza resistance to neuraminidase inhibitors in the N1 and N2 genetic backgrounds.
Abed Y, Baz M, Boivin G.
Antivir Ther. 2006;11(8):971-6.
In silico identification of the potential drug resistance sites over 2009 influenza A (H1N1) virus neuraminidase.
Liu H, Yao X, Wang C, Han J.
Mol Pharm. 2010 Jun 7;7(3):894-904.
Characterization of drug-resistant recombinant influenza A/H1N1 viruses selected in vitro with peramivir and zanamivir.
Baz M, Abed Y, Boivin G.
Antiviral Res. 2007 May;74(2):159-62. Epub 2006 Nov 20.
Zanamivir-resistant influenza viruses with a novel neuraminidase mutation.
Hurt AC, Holien JK, Parker M, Kelso A, Barr IG.
J Virol. 2009 Oct;83(20):10366-73. Epub 2009 Jul 29.
Binding interaction analysis of the active site and its inhibitors for neuraminidase (N1 subtype) of human influenza virus by the integration of molecular docking, FMO calculation and 3D-QSAR CoMFA modeling.
Zhang Q, Yang J, Liang K, Feng L, Li S, Wan J, Xu X, Yang G, Liu D, Yang S.
J Chem Inf Model. 2008 Sep;48(9):1802-12. Epub 2008 Aug 16.
The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site.
Li Q, Qi J, Zhang W, Vavricka CJ, Shi Y, Wei J, Feng E, Shen J, Chen J, Liu D, He J, Yan J, Liu H, Jiang H, Teng M, Li X, Gao GF.
Nat Struct Mol Biol. 2010 Oct;17(10):1266-8. Epub 2010 Sep 19.
Structural and antigenic variance between novel influenza A/H1N1/2009 and influenza A/H1N1/2008 viruses.
Saxena SK, Mishra N, Saxena R, Swamy ML, Sahgal P, Saxena S, Tiwari S, Mathur A, Nair MP.
J Infect Dev Ctries. 2009 Nov 26;4(1):1-6.
Computational analysis and modeling the effectiveness of 'Zanamivir' targeting neuraminidase protein in pandemic H1N1 strains.
Gupta SK, Gupta SK, Smita S, Srivastava M, Lai X, Schmitz U, Rahman Q, Wolkenhauer O, Vera J.
Infect Genet Evol. 2011 Jul;11(5):1072-82. Epub 2011 Apr 2.
[Impact of avian influenza virus H5N1 neuraminidase mutations on the activity of neuraminidase and the sensibility to neuraminidase inhibitors].
Chen Z, Zheng YH, Lin Y, Collins PJ, Hay AJ.
Zhonghua Yi Xue Za Zhi. 2010 Jul 20;90(27):1924-8. Chinese.
A new and rapid genotypic assay for the detection of neuraminidase inhibitor resistant influenza A viruses of subtype H1N1, H3N2, and H5N1.
Duwe S, Schweiger B.
J Virol Methods. 2008 Nov;153(2):134-41. Epub 2008 Sep 19.
Filter your results:
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on