PubMed

Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-alpha and matrix metalloproteinase-13 in human chondrocytes.

Rasheed Z, Anbazhagan AN, Akhtar N, Ramamurthy S, Voss FR, Haqqi TM.

Arthritis Res Ther. 2009;11(3):R71. Epub 2009 May 15.PMID: 19445683 [PubMed - in process]Related articlesFree article

Epigallocatechin-3-gallate inhibits interleukin-1beta-induced expression of nitric oxide synthase and production of nitric oxide in human chondrocytes: suppression of nuclear factor kappaB activation by degradation of the inhibitor of nuclear factor kappaB.

Singh R, Ahmed S, Islam N, Goldberg VM, Haqqi TM.

Arthritis Rheum. 2002 Aug;46(8):2079-86.PMID: 12209512 [PubMed - indexed for MEDLINE]Related articlesFree article

Epigallocatechin-3-gallate selectively inhibits interleukin-1beta-induced activation of mitogen activated protein kinase subgroup c-Jun N-terminal kinase in human osteoarthritis chondrocytes.

Singh R, Ahmed S, Malemud CJ, Goldberg VM, Haqqi TM.

J Orthop Res. 2003 Jan;21(1):102-9.PMID: 12507586 [PubMed - indexed for MEDLINE]Related articles

Punica granatum L. extract inhibits IL-1beta-induced expression of matrix metalloproteinases by inhibiting the activation of MAP kinases and NF-kappaB in human chondrocytes in vitro.

Ahmed S, Wang N, Hafeez BB, Cheruvu VK, Haqqi TM.

J Nutr. 2005 Sep;135(9):2096-102.PMID: 16140882 [PubMed - indexed for MEDLINE]Related articlesFree article

Green tea polyphenol epigallocatechin-3-gallate (EGCG) differentially inhibits interleukin-1 beta-induced expression of matrix metalloproteinase-1 and -13 in human chondrocytes.

Ahmed S, Wang N, Lalonde M, Goldberg VM, Haqqi TM.

J Pharmacol Exp Ther. 2004 Feb;308(2):767-73. Epub 2003 Nov 4.PMID: 14600251 [PubMed - indexed for MEDLINE]Related articlesFree article

Phenyl N-tert-butylnitrone down-regulates interleukin-1 beta-stimulated matrix metalloproteinase-13 gene expression in human chondrocytes: suppression of c-Jun NH2-terminal kinase, p38-mitogen-activated protein kinase and activating protein-1.

Ahmed S, Rahman A, Hasnain A, Goldberg VM, Haqqi TM.

J Pharmacol Exp Ther. 2003 Jun;305(3):981-8. Epub 2003 Mar 6.PMID: 12626640 [PubMed - indexed for MEDLINE]Related articlesFree article

(-)-Epigallocatechin-3-gallate promotes pro-matrix metalloproteinase-7 production via activation of the JNK1/2 pathway in HT-29 human colorectal cancer cells.

Kim M, Murakami A, Kawabata K, Ohigashi H.

Carcinogenesis. 2005 Sep;26(9):1553-62. Epub 2005 Apr 28.PMID: 15860507 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment of epigallocatechin-3-gallate inhibits matrix metalloproteinases-2 and -9 via inhibition of activation of mitogen-activated protein kinases, c-jun and NF-kappaB in human prostate carcinoma DU-145 cells.

Vayalil PK, Katiyar SK.

Prostate. 2004 Apr 1;59(1):33-42.PMID: 14991864 [PubMed - indexed for MEDLINE]Related articles

Association of suppression of extracellular signal-regulated kinase phosphorylation by epigallocatechin gallate with the reduction of matrix metalloproteinase activities in human fibrosarcoma HT1080 cells.

Maeda-Yamamoto M, Suzuki N, Sawai Y, Miyase T, Sano M, Hashimoto-Ohta A, Isemura M.

J Agric Food Chem. 2003 Mar 26;51(7):1858-63.PMID: 12643642 [PubMed - indexed for MEDLINE]Related articles

alpha-MSH inhibits TNF-alpha-induced matrix metalloproteinase-13 expression by modulating p38 kinase and nuclear factor kappaB signaling in human chondrosarcoma HTB-94 cells.

Yoon SW, Chun JS, Sung MH, Kim JY, Poo H.

Osteoarthritis Cartilage. 2008 Jan;16(1):115-24. Epub 2007 Aug 1.PMID: 17683952 [PubMed - indexed for MEDLINE]Related articles

Phase 2 enzyme inducer sulphoraphane blocks matrix metalloproteinase production in articular chondrocytes.

Kim HA, Yeo Y, Kim WU, Kim S.

Rheumatology (Oxford). 2009 Aug;48(8):932-8. Epub 2009 Jun 2.PMID: 19491303 [PubMed - indexed for MEDLINE]Related articles

Tumor necrosis factor-alpha induces MMP-9 expression via p42/p44 MAPK, JNK, and nuclear factor-kappaB in A549 cells.

Lin CC, Tseng HW, Hsieh HL, Lee CW, Wu CY, Cheng CY, Yang CM.

Toxicol Appl Pharmacol. 2008 Jun 15;229(3):386-98. Epub 2008 Feb 9.PMID: 18336852 [PubMed - indexed for MEDLINE]Related articles

Retinoic acid blocks pro-inflammatory cytokine-induced matrix metalloproteinase production by down-regulating JNK-AP-1 signaling in human chondrocytes.

Ho LJ, Lin LC, Hung LF, Wang SJ, Lee CH, Chang DM, Lai JH, Tai TY.

Biochem Pharmacol. 2005 Jul 15;70(2):200-8.PMID: 15946654 [PubMed - indexed for MEDLINE]Related articles

Activation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study.

Boileau C, Amiable N, Martel-Pelletier J, Fahmi H, Duval N, Pelletier JP.

Arthritis Res Ther. 2007;9(6):R121.PMID: 18031579 [PubMed - indexed for MEDLINE]Related articlesFree article

Multifunctional effect of epigallocatechin-3-gallate (EGCG) in downregulation of gelatinase-A (MMP-2) in human breast cancer cell line MCF-7.

Sen T, Moulik S, Dutta A, Choudhury PR, Banerji A, Das S, Roy M, Chatterjee A.

Life Sci. 2009 Feb 13;84(7-8):194-204. Epub 2008 Dec 3.PMID: 19105967 [PubMed - indexed for MEDLINE]Related articles

Green tea polyphenol EGCG suppresses cigarette smoke condensate-induced NF-kappaB activation in normal human bronchial epithelial cells.

Syed DN, Afaq F, Kweon MH, Hadi N, Bhatia N, Spiegelman VS, Mukhtar H.

Oncogene. 2007 Feb 1;26(5):673-82. Epub 2006 Jul 24.PMID: 16862172 [PubMed - indexed for MEDLINE]Related articles

IL-1 beta promotes A549 cell migration via MAPKs/AP-1- and NF-kappaB-dependent matrix metalloproteinase-9 expression.

Lin CC, Kuo CT, Cheng CY, Wu CY, Lee CW, Hsieh HL, Lee IT, Yang CM.

Cell Signal. 2009 Nov;21(11):1652-62. Epub 2009 Jul 16.PMID: 19616091 [PubMed - indexed for MEDLINE]Related articles

The catabolic pathway mediated by Toll-like receptors in human osteoarthritic chondrocytes.

Kim HA, Cho ML, Choi HY, Yoon CS, Jhun JY, Oh HJ, Kim HY.

Arthritis Rheum. 2006 Jul;54(7):2152-63.PMID: 16802353 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparative effects of 2 antioxidants, selenomethionine and epigallocatechin-gallate, on catabolic and anabolic gene expression of articular chondrocytes.

Andriamanalijaona R, Kypriotou M, Baugé C, Renard E, Legendre F, Raoudi M, Boumediene K, Gatto H, Monginoux P, Pujol JP.

J Rheumatol. 2005 Oct;32(10):1958-67. Erratum in: J Rheumatol. 2005 Dec;32(12):2502. PMID: 16206353 [PubMed - indexed for MEDLINE]Related articles

COX-2 and iNOS are critical in advanced glycation end product-activated chondrocytes in vitro.

Huang CY, Hung LF, Liang CC, Ho LJ.

Eur J Clin Invest. 2009 May;39(5):417-28.PMID: 19371268 [PubMed - indexed for MEDLINE]Related articles