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Rejuvenation in older adults receiving oral ghrelin.

Rafael H.

Ann Intern Med. 2009 May 5;150(9):653-4; author reply 655. No abstract available. PMID: 19414850 [PubMed - indexed for MEDLINE]Related articlesFree article

Rejuvenation in older adults receiving oral ghrelin.

Gaugg M.

Ann Intern Med. 2009 May 5;150(9):654; author reply 655. No abstract available. PMID: 19414852 [PubMed - indexed for MEDLINE]Related articlesFree article

Rejuvenation in older adults receiving oral ghrelin.

Webster J.

Ann Intern Med. 2009 May 5;150(9):654-5; author reply 655. No abstract available. PMID: 19414853 [PubMed - indexed for MEDLINE]Related articlesFree article

Summaries for patients. Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults.

[No authors listed]

Ann Intern Med. 2008 Nov 4;149(9):I-36. No abstract available. PMID: 18981483 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of growth hormone secretagogues to prevent or treat the effects of aging: not yet ready for prime time.

Blackman MR.

Ann Intern Med. 2008 Nov 4;149(9):677-9. No abstract available. PMID: 18981489 [PubMed - indexed for MEDLINE]Related articlesFree article

Sarcopenia and the elusive fountain of youth.

Hanauer SB.

Nat Clin Pract Gastroenterol Hepatol. 2009 Jan;6(1):1. No abstract available. PMID: 19127276 [PubMed - indexed for MEDLINE]Related articles

Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjects.

Chapman IM, Bach MA, Van Cauter E, Farmer M, Krupa D, Taylor AM, Schilling LM, Cole KY, Skiles EH, Pezzoli SS, Hartman ML, Veldhuis JD, Gormley GJ, Thorner MO.

J Clin Endocrinol Metab. 1996 Dec;81(12):4249-57.PMID: 8954023 [PubMed - indexed for MEDLINE]Related articles

Effects of a 7-day treatment with a novel, orally active, growth hormone (GH) secretagogue, MK-677, on 24-hour GH profiles, insulin-like growth factor I, and adrenocortical function in normal young men.

Copinschi G, Van Onderbergen A, L'Hermite-Balériaux M, Mendel CM, Caufriez A, Leproult R, Bolognese JA, De Smet M, Thorner MO, Van Cauter E.

J Clin Endocrinol Metab. 1996 Aug;81(8):2776-82.PMID: 8768828 [PubMed - indexed for MEDLINE]Related articles

Effects of oral administration of ibutamoren mesylate, a nonpeptide growth hormone secretagogue, on the growth hormone-insulin-like growth factor I axis in growth hormone-deficient children.

Codner E, Cassorla F, Tiulpakov AN, Mericq MV, Avila A, Pescovitz OH, Svensson J, Cerchio K, Krupa D, Gertz BJ, Murphy G.

Clin Pharmacol Ther. 2001 Jul;70(1):91-8.PMID: 11452249 [PubMed - indexed for MEDLINE]Related articles

Discrepancy between serum leptin values and total body fat in response to the oral growth hormone secretagogue MK-677.

Svensson J, Carlsson B, Carlsson LM, Jansson JO, Bengtsson BA.

Clin Endocrinol (Oxf). 1999 Apr;50(4):451-6.PMID: 10468903 [PubMed - indexed for MEDLINE]Related articles

Effect of dehydroepiandrosterone supplementation on bone mineral density, bone markers, and body composition in older adults: the DAWN trial.

von Mühlen D, Laughlin GA, Kritz-Silverstein D, Bergstrom J, Bettencourt R.

Osteoporos Int. 2008 May;19(5):699-707. Epub 2007 Dec 15.PMID: 18084691 [PubMed - indexed for MEDLINE]Related articlesFree article

Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue MK-677 increases GH secretion, fat-free mass, and energy expenditure.

Svensson J, Lönn L, Jansson JO, Murphy G, Wyss D, Krupa D, Cerchio K, Polvino W, Gertz B, Boseaus I, Sjöström L, Bengtsson BA.

J Clin Endocrinol Metab. 1998 Feb;83(2):362-9.PMID: 9467542 [PubMed - indexed for MEDLINE]Related articlesFree article

Design and biological activities of L-163,191 (MK-0677): a potent, orally active growth hormone secretagogue.

Patchett AA, Nargund RP, Tata JR, Chen MH, Barakat KJ, Johnston DB, Cheng K, Chan WW, Butler B, Hickey G, et al.

Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):7001-5.PMID: 7624358 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment with the oral growth hormone secretagogue MK-677 increases markers of bone formation and bone resorption in obese young males.

Svensson J, Ohlsson C, Jansson JO, Murphy G, Wyss D, Krupa D, Cerchio K, Polvino W, Gertz B, Baylink D, Mohan S, Bengtsson BA.

J Bone Miner Res. 1998 Jul;13(7):1158-66.PMID: 9661080 [PubMed - indexed for MEDLINE]Related articles

Synthesis and biological activities of spiroheterocyclic growth hormone secretagogues.

Chen MH, Pollard PP, Patchett AA, Cheng K, Wei L, Chan WW, Butler B, Jacks TM, Smith RG.

Bioorg Med Chem Lett. 1999 May 3;9(9):1261-6.PMID: 10340611 [PubMed - indexed for MEDLINE]Related articles

MK-0677, a potent, novel, orally active growth hormone (GH) secretagogue: GH, insulin-like growth factor I, and other hormonal responses in beagles.

Jacks T, Smith R, Judith F, Schleim K, Frazier E, Chen H, Krupa D, Hora D Jr, Nargund R, Patchett A, Hickey G.

Endocrinology. 1996 Dec;137(12):5284-9.PMID: 8940347 [PubMed - indexed for MEDLINE]Related articles

Clinical and experimental effects of growth hormone secretagogues on various organ systems.

Svensson JA, Bengtsson B.

Horm Res. 1999;51 Suppl 3:16-20. Review.PMID: 10592439 [PubMed - indexed for MEDLINE]Related articles

Phase I study of oral spirogermanium.

Harvey J, McFadden M, Smith FP, Joubert L, Schein PS.

Invest New Drugs. 1990 Feb;8(1):53-6.PMID: 2345069 [PubMed - indexed for MEDLINE]Related articles

Peripheral ghrelin treatment stabilizes body weights of senescent male Brown Norway rats at baseline and after surgery.

Yukawa M, Weigle DS, Davis CD, Marck BT, Wolden-Hanson T.

Am J Physiol Regul Integr Comp Physiol. 2008 May;294(5):R1453-60. Epub 2008 Mar 12.PMID: 18337314 [PubMed - indexed for MEDLINE]Related articles

Treatment of obese subjects with the oral growth hormone secretagogue MK-677 affects serum concentrations of several lipoproteins, but not lipoprotein(a).

Svensson J, Jansson JO, Ottosson M, Johannsson G, Taskinen MR, Wiklund O, Bengtsson BA.

J Clin Endocrinol Metab. 1999 Jun;84(6):2028-33.PMID: 10372705 [PubMed - indexed for MEDLINE]Related articlesFree article