PubMed

Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.

Takeuchi F, Serizawa M, Yamamoto K, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Katsuya T, Miyagishi M, Nakashima N, Nawata H, Nakamura J, Kono S, Takayanagi R, Kato N.

Diabetes. 2009 Jul;58(7):1690-9. Epub 2009 Apr 28.PMID: 19401414 [PubMed - indexed for MEDLINE]Related articlesFree article

Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening.

Tabara Y, Osawa H, Kawamoto R, Onuma H, Shimizu I, Miki T, Kohara K, Makino H.

Diabetes. 2009 Feb;58(2):493-8. Epub 2008 Nov 25.PMID: 19033397 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.

Wu Y, Li H, Loos RJ, Yu Z, Ye X, Chen L, Pan A, Hu FB, Lin X.

Diabetes. 2008 Oct;57(10):2834-42. Epub 2008 Jul 15.PMID: 18633108 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population.

Lee YH, Kang ES, Kim SH, Han SJ, Kim CH, Kim HJ, Ahn CW, Cha BS, Nam M, Nam CM, Lee HC.

J Hum Genet. 2008;53(11-12):991-8. Epub 2008 Nov 11.PMID: 18991055 [PubMed - indexed for MEDLINE]Related articles

Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.

Omori S, Tanaka Y, Takahashi A, Hirose H, Kashiwagi A, Kaku K, Kawamori R, Nakamura Y, Maeda S.

Diabetes. 2008 Mar;57(3):791-5. Epub 2007 Dec 27.PMID: 18162508 [PubMed - indexed for MEDLINE]Related articlesFree article

Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians.

Ng MC, Park KS, Oh B, Tam CH, Cho YM, Shin HD, Lam VK, Ma RC, So WY, Cho YS, Kim HL, Lee HK, Chan JC, Cho NH.

Diabetes. 2008 Aug;57(8):2226-33. Epub 2008 May 9.PMID: 18469204 [PubMed - indexed for MEDLINE]Related articlesFree article

Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan.

Horikawa Y, Miyake K, Yasuda K, Enya M, Hirota Y, Yamagata K, Hinokio Y, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino Y, Maegawa H, Kashiwagi A, Yamamoto K, Tokunaga K, Takeda J, Kasuga M.

J Clin Endocrinol Metab. 2008 Aug;93(8):3136-41. Epub 2008 May 13.PMID: 18477659 [PubMed - indexed for MEDLINE]Related articlesFree article

Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians.

Rong R, Hanson RL, Ortiz D, Wiedrich C, Kobes S, Knowler WC, Bogardus C, Baier LJ.

Diabetes. 2009 Feb;58(2):478-88. Epub 2008 Nov 13.PMID: 19008344 [PubMed - indexed for MEDLINE]Related articlesFree article

Variants of the PPARG, IGF2BP2, CDKAL1, HHEX, and TCF7L2 genes confer risk of type 2 diabetes independently of BMI in the German KORA studies.

Herder C, Rathmann W, Strassburger K, Finner H, Grallert H, Huth C, Meisinger C, Gieger C, Martin S, Giani G, Scherbaum WA, Wichmann HE, Illig T.

Horm Metab Res. 2008 Oct;40(10):722-6. Epub 2008 Jul 2.PMID: 18597214 [PubMed - indexed for MEDLINE]Related articles

Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies.

Grarup N, Rose CS, Andersson EA, Andersen G, Nielsen AL, Albrechtsen A, Clausen JO, Rasmussen SS, Jørgensen T, Sandbaek A, Lauritzen T, Schmitz O, Hansen T, Pedersen O.

Diabetes. 2007 Dec;56(12):3105-11. Epub 2007 Sep 7.PMID: 17827400 [PubMed - indexed for MEDLINE]Related articlesFree article

Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program.

Moore AF, Jablonski KA, McAteer JB, Saxena R, Pollin TI, Franks PW, Hanson RL, Shuldiner AR, Knowler WC, Altshuler D, Florez JC; Diabetes Prevention Program Research Group.

Diabetes. 2008 Sep;57(9):2503-10. Epub 2008 Jun 10.PMID: 18544707 [PubMed - indexed for MEDLINE]Related articlesFree article

Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value.

Cauchi S, Meyre D, Durand E, Proença C, Marre M, Hadjadj S, Choquet H, De Graeve F, Gaget S, Allegaert F, Delplanque J, Permutt MA, Wasson J, Blech I, Charpentier G, Balkau B, Vergnaud AC, Czernichow S, Patsch W, Chikri M, Glaser B, Sladek R, Froguel P.

PLoS One. 2008 May 7;3(5):e2031.PMID: 18461161 [PubMed - indexed for MEDLINE]Related articlesFree article

Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies.

Lewis JP, Palmer ND, Hicks PJ, Sale MM, Langefeld CD, Freedman BI, Divers J, Bowden DW.

Diabetes. 2008 Aug;57(8):2220-5. Epub 2008 Apr 28.PMID: 18443202 [PubMed - indexed for MEDLINE]Related articlesFree article

Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study.

van Hoek M, Dehghan A, Witteman JC, van Duijn CM, Uitterlinden AG, Oostra BA, Hofman A, Sijbrands EJ, Janssens AC.

Diabetes. 2008 Nov;57(11):3122-8. Epub 2008 Aug 11.PMID: 18694974 [PubMed - indexed for MEDLINE]Related articlesFree article

Strong association of common variants in the CDKN2A/CDKN2B region with type 2 diabetes in French Europids.

Duesing K, Fatemifar G, Charpentier G, Marre M, Tichet J, Hercberg S, Balkau B, Froguel P, Gibson F.

Diabetologia. 2008 May;51(5):821-6. Epub 2008 Mar 27.PMID: 18368387 [PubMed - indexed for MEDLINE]Related articles

Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population.

Horikoshi M, Hara K, Ito C, Shojima N, Nagai R, Ueki K, Froguel P, Kadowaki T.

Diabetologia. 2007 Dec;50(12):2461-6. Epub 2007 Oct 10.PMID: 17928989 [PubMed - indexed for MEDLINE]Related articles

Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk.

Sanghera DK, Ortega L, Han S, Singh J, Ralhan SK, Wander GS, Mehra NK, Mulvihill JJ, Ferrell RE, Nath SK, Kamboh MI.

BMC Med Genet. 2008 Jul 3;9:59.PMID: 18598350 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.

Stancáková A, Kuulasmaa T, Paananen J, Jackson AU, Bonnycastle LL, Collins FS, Boehnke M, Kuusisto J, Laakso M.

Diabetes. 2009 Sep;58(9):2129-36. Epub 2009 Jun 5.PMID: 19502414 [PubMed - indexed for MEDLINE]Related articles

Examination of type 2 diabetes loci implicates CDKAL1 as a birth weight gene.

Zhao J, Li M, Bradfield JP, Wang K, Zhang H, Sleiman P, Kim CE, Annaiah K, Glaberson W, Glessner JT, Otieno FG, Thomas KA, Garris M, Hou C, Frackelton EC, Chiavacci RM, Berkowitz RI, Hakonarson H, Grant SF.

Diabetes. 2009 Oct;58(10):2414-8. Epub 2009 Jul 10.PMID: 19592620 [PubMed - indexed for MEDLINE]Related articles

Replication study for the association of new meta-analysis-derived risk loci with susceptibility to type 2 diabetes in 6,244 Japanese individuals.

Omori S, Tanaka Y, Horikoshi M, Takahashi A, Hara K, Hirose H, Kashiwagi A, Kaku K, Kawamori R, Kadowaki T, Nakamura Y, Maeda S.

Diabetologia. 2009 Aug;52(8):1554-60. Epub 2009 May 20.PMID: 19455301 [PubMed - indexed for MEDLINE]Related articles